Your Road to Wellness

Inflammation

Can green tea extract help prevent influenza virus?

Posted by on 9:00 am Antioxidents, Cholesterol, Green tea, Inflammation | 0 comments

influenza virus

 

Viral infections are a constant threat. Every year people get sick from the influenza virus.
In addition to eating healthy and being physically active, what else can you do?
How about using green tea.
Researchers in Japan tried to find additional resources and investigated if capsules with green
tea extract including catechins and theanine could be effective in preventing the flu (Matsumoto
K, et al, 2011).
This was a randomized, double-blind, placebo-controlled trial of 200 healthcare workers
conducted for 5 months.
The researchers found that the incidence of clinically defined influenza infection was
significantly lower in the catechin/theanine group.

 

 

Research has also shown that green tea extract lowers blood pressure, total cholesterol, LDL
(the bad cholesterol), and inflammation (Nantz MP, et al 2009). These are all risk factors for
cardiovascular disease.
It is also important what green tea can do for the brain. Green tea may provide neuroprotection
and has been associated with a lower prevalence of cognitive impairment (Kuriyama S, et al
2006).

References:

Kuriyama S, Hozawa A, Ohmori K, Shimazu T, Matsui T, Ebihara S, Awata S, Nagatomi R, Arai H,
Tsuji I. Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya
Project. American Journal of Clinical Nutrition, Vol. 83, No. 2, 355-361, February 2006.

Matsumoto K, Yamada H, Takuma N, Niino H, Sagesaka YM.
Effects of green tea catechins and theanine on preventing influenza infection among
healthcare workers: a randomized controlled trial. BMC Complement Altern Med. 2011
Feb 21;11:15.

Nantz MP, Rowe CA, Bukowski JF, Percival SS. Standardized capsule of Camellia sinensis lowers
cardiovascular risk factors in a randomized, double-blind, placebo-controlled study. Nutrition. 2009
Feb; 25(2):147-54. Epub 2008 Oct 9.

 

BETTER GREEN TEA

better green tea

Polyphenols (catechins) are the active ingredients in green tea providing a variety of benefits.

Green tea extract has been documented to lower blood pressure, reduce total cholesterol and LDL (the bad cholesterol), reduce serum amyloid-alpha (a marker of chronic inflammation) and reduce malondialdehyde (a marker of oxidative stress) (Nantz MP, et al. 2009). These are all cardiovascular risk factors and they were reduced in only 3 weeks.

Green tea may provide neuroprotection and has been associated with a lower prevalence of cognitive impairment.

A study including 41,761 participants found that green tea consumption was associated with a reduced risk of liver cancer.

Green tea polyphenols have been documented to reduce serum biomarkers in patients with prostate cancer.

Regular drinking of green tea has been associated with a slightly decreased risk of breast cancer (Shrubsole MJ, et al. 2008).

Green tea consumption was inversely associated with psychological distress in an assessment of 42,093 individuals. Consumption of 4 cups or more of green tea has been associated with a lower prevalence of depressive symptoms.

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Can this prevent early mortality? Let’s look at the research.

Posted by on 9:00 am Fish Oil, General Health, Inflammation, Omega-3, fish oil | 0 comments

telomeres

 

Telomeres are structures found at the end of our chromosomes. They help protect genetic
information.
Shorter telomeres have been associated with poor health behaviors, age-related diseases, and
early mortality.
Telomere length can for that reason be one way to estimate how fast we age. As we age
telomeres get shorter. If we can slow down the process that shortens the telomeres or even
better, lengthens them, we should be better off.
Telomere length is regulated by the enzyme telomerase and is linked to exposure to
proinflammatory cytokines and oxidative stress.

 

 

The following study investigated whether omega 3 fatty acid supplementation could affect
telomere length, telomerase, and oxidative stress (Kiecolt-Glaser, JK, et al., 2013).
The participants were 106 healthy sedentary overweight middle-aged and older adults who
received either 2.5g or 1.25g per day of omega 3 supplements, or placebo capsules that had
the proportions of the fatty acids in a typical American diet.
The results showed that the omega 3 fatty acids significantly lowered oxidative stress.
The researchers also found that telomere length increased with decreasing omega 6 fatty
acid to omega 3 fatty acid ratio.
This suggests that a lower omega 6 fatty acid to omega 3 fatty acid ratio can impact cell aging.

Most people in the western world ingest too much omega 6 fat from vegetable oils and too little
omega 3 fatty acids.
It is the ratio that is really important, because omega 6 fat converts to arachidonic acid, a
precursor for inflammation, while the omega 3 fatty acids EPA and DHA reduce inflammation.
The easiest way to increase the intake of EPA and DHA is by taking omega 3 fish oil capsules.
It is however important that the fish oil is processed correctly to remove toxins since all fish is
now more or less contaminated.
Fish oil in the form of triglycerides is more stable and also better absorbed than the more
a common form of ethyl ester which is cheaper to manufacture.

 

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Reference:

Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS,
Blackburn E. Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A
randomized controlled trial.Brain Behav Immun. 2013 Feb;28:16-24.

 

Most people that eat a western diet can benefit from increasing the intake of Omega 3 fatty acids since their diet usually contains too much Omega 6 from vegetable oils and saturated fat from dairy and other animal sources. Research has shown many health benefits from Omega 3 fat intake. Several studies are showing evidence that the protective benefits of fish oil prevent death from heart disease

The anti-inflammatory effects of Omega 3 fatty acids are well known. Several studies on rheumatoid arthritis using supplements with EPA/DHA, which is found in fish oil, have shown to decrease morning stiffness and reduce the number of painful and swollen joints. Fish oil has also shown to help in the treatment of colitis

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What’s important for the cardiovascular system is also important for the immune system.

Posted by on 9:00 am BMI, Body fat, Body mass index, Cardiovascular Disease, Cardiovascular disease & waist-hip ratio, Diet, Eating, General Health, Health Risk, Inflammation, Weight, Weight loss | 0 comments

obese man with burgers

 

In this study, participants taking berberine when compared to the placebo group saw a
reduction in triglycerides by 35.9% total cholesterol by 18.1% and LDL (low-density lipoprotein),
the so-called bad cholesterol by 21.1% (Zhang Y, et.al., 2008).

Patients with metabolic syndrome treated with berberine for 3 months showed a decrease in
their BMI (body mass index) from 31.5 to 27.4 in this study (Yang J, et.al., 2012).
Patients diagnosed with the metabolic syndrome usually have several symptoms, they are
insulin resistant, have increased waist circumference and high blood pressure.
The same research also showed that berberine decreased leptin levels from 8.01 to 5.12 μg/L.
Leptin is a hormone that suppresses food intake and induces weight loss. Obese patients are
usually leptin-resistant.

 

 

When 10 studies were reviewed both BMI and waist circumference decreased in participants
taking berberine (Xiong P, et.al.,2020).

It is important to produce a balanced immune response when needed.
An overreaction of the immune system will cause damage and is harmful. It can actually kill us.
Some people are killed by an overreaction of their immune system, not from the invading virus
or bacteria.

This research showed that berberine had an anti-inflammatory effect and initiated a more
balanced immune response (Kalmarzi RN, et.al.,2019).
Inflammation is also a risk factor for cardiovascular disease.

When researchers treated patients with the acute coronary syndrome with berberine, they found
that several inflammatory markers were reduced, C-reactive protein and interleukin-6 were 2 of
them (Meng S, et.al., 2012).

Berberine has shown to be a very useful plant-derived compound benefitting important
functions from blood glucose metabolism, cardiovascular function, fat storage, immune
system and inflammation.

These functions are interconnected, that is why berberine is such a valuable substance.

 

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References:

Kalmarzi RN, Naleini SN, Ashtary-Larky D, Peluso I, Jouybari L, Rafi A, Ghorat F, Heidari N,
Sharifian F, Mardaneh J, Aiello P4, Helbi S, Kooti W.Anti-Inflammatory and Immunomodulatory
Effects of Barberry ( Berberis vulgaris ) and Its Main Compounds.Oxid Med Cell Longev. 2019
Nov 19;2019:6183965.

Meng S, Wang LS, Huang ZQ, Zhou Q, Sun YG, Cao JT, Li YG, Wang CQ. Berberine
ameliorates inflammation in patients with acute coronary syndrome following percutaneous
coronary intervention. Clin Exp Pharmacol Physiol. 2012 May;39(5):406-11.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Berberine improves insulin sensitivity by
inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic
syndrome patients. Evid Based Complement Alternat Med. 2012;2012:363845

Xiong P, Niu L, Talaei S, Kord-Varkaneh H, Clark CCT, Găman MA, Rahmani J, Dorosti M,
Mousavi SM, Zarezadeh M, Taghizade-Bilondi H, Zhang J. The effect of berberine
supplementation on obesity indices: A dose- response meta-analysis and systematic review of
randomized controlled trials. Complement Ther Clin Pract. 2020 May;39:101113.

 

glucose metabolism supportThis formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

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2 important things to help you stay healthy and feel good.

Posted by on 9:00 am Diabetes, Diet, Eating, Energy, Health, Health Risk, Inflammation, Inflammatory factor, Low glycemic meals, Stay healthy, Supplements, Supplements for Conditions, Supplements List, Type 1 diabetes, Type 2 diabetes | 0 comments

blood glucose food

 

You need to keep your glucose metabolism healthy by keeping your blood glucose at a low and
normal level.
There are several reasons why this is important. When your blood glucose is elevated to a high
level as it tends to be when we get insulin resistant, and when we eat high glycemic index food,
we usually get tired.
Elevated blood glucose also leads to increased low-grade inflammation, and inflammation is the
the second thing you need to keep low to stay healthy.
Increasing CRP, an inflammatory marker, has been found with higher fasting glucose levels,
even among subjects with fasting glucose in the normal range (Aronson D. et.al., 2004).

 

 

Eating high nutrient, low glycemic index meals are important, and so is exercise.
There is however something else you also can do to keep your blood glucose lower.
You can take berberine, a natural plant derivative.
Berberine has shown to provide several health benefits. One of them is keeping the blood
glucose at a lower, normal level.

In the following study participants with type 2 diabetes were randomized to take either berberine
or metformin (a diabetic medication) for 3 months (Yin J, et.al., 2008).
The effect of berberine was found to be similar to metformin.
A significant decrease in hemoglobin A1c from 9.5% to 7.5% was found when taking berberine.
Hemoglobin A1c is a measurement of long term glucose control.
Fasting blood glucose was reduced with 34.9%, postprandial blood glucose with 43.9%, and
plasma triglycerides with 21.2%. Postprandial glucose is the blood glucose measured after a
meal.
The insulin resistance index was reduced by 44.7%.
Another study which included 116 patients also with type 2 diabetes showed similar results
(Zhang Y, et.al., 2008).
In these studies, the participants had type 2 diabetes which means they were severely insulin
resistant.
There is no reason to wait until we get a serious disease before taking action.
Berberine can be used to help keep glucose metabolism healthy.

 

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References

Aronson D, Bartha P, Zinder O, Kerner A, Shitman E, Markiewicz W, Brook GJ, Levy
Y. Association between fasting glucose and C-reactive protein in middle-aged subjects.
Diabet Med. 2004 Jan;21(1):39-44.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism.
2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013.

glucose metabolism support

This formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

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Can you use your mind to impact your immune system, and reduce your response to stress?

Posted by on 9:00 am Inflammation, Meditation, Stress | 0 comments

Illusion of Mind

 

This research evaluated the effect of compassion meditation on immune, neuroendocrine and
behavioral responses to psychosocial stress.
61 healthy adults were randomly allocated to either 6 weeks of practice in compassion
meditation or participation in a health discussion control group (Paace TW, et.al., 2009).

The researchers found that increased meditation practice was correlated with decreased
stress test induced IL-6, an inflammatory marker, and also decreased distress scores.

In the following study 25 people participating in an 8-week program practicing mindfulness
meditation were compared with a control group not meditating (Davidson RJ, et.al., 2003).
At the end of the 8-week period, the participants in both groups were vaccinated with the influenza
vaccine.

 

 

Significant increases in antibody titers to influenza vaccine were found among subjects in the
meditation group compared with those in the control group.

This means that the participants practicing meditation had a better immune response.

To see the benefits of meditation you need to practice regularly, but that’s well worth it since
meditation has shown to provide many benefits.
Decide that you are going to start meditating, and set aside specific times for it, put it on your
schedule. That’s how you will get it done.

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References:

Davidson RJ, Kabat-Zinn J, Schumacher J, Rosenkranz M, Muller D, Santorelli SF, Urbanowski
F, Harrington A, Bonus K, Sheridan JF. Alterations in brain and immune function produced by
mindfulness meditation. Psychosom Med. 2003 Jul-Aug;65(4):564-70.

Pace TW, Negi LT, Adame DD, Cole SP, Sivilli TI, Brown TD, Issa MJ, Raison CL. Effect of
compassion meditation on neuroendocrine, innate immune and behavioral responses to
psychosocial stress. Psychoneuroendocrinology. 2009 Jan;34(1):87-98.

 

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Can reduction of inflammation improve the recovery of low back pain?

Posted by on 9:00 am Inflammation, Lower Back Pain and Neck Pain, Supplements List | 0 comments

lower back pain

 

This research included 155 women 65 years or older with acute low back pain (Queiroz BZ, et.al., 2017).
The researchers showed a relationship between inflammation and low back pain, establishing that low IL-6 levels (an inflammatory marker) preceded the recovery. This supports that proinflammatory cytokines promote pain.

In the first year after an acute episode of low back pain, there was a decrease in the severity of low back pain corresponding to decreased levels of IL-6 and TNF-α, another inflammatory marker.

 

 

The researcher concluded that the probability of occurrence of pain relief at the 12-month
follow-up was 2.22 times higher in elderly women who had low levels of IL-6.

Systemic inflammation is linked with the development and persistence of many pathological pain states (Klyne DM, et.al., 2017).
Both CRP, an inflammatory marker, and IL-6 were higher in study participants with acute low back pain compared with controls, and they were also higher in the participants with more pain compared with those who had less pain?
The researchers said these findings suggest systemic CRP and IL-6 are important contributors to
inflammation in the early phase of low back pain and that various factors can shape these responses.

A plant-based low glycemic index diet can be very effective in reducing systemic inflammation.
Research has also shown plant-derived compounds in supplemental form to reduce free radicals and inflammation.

 

References:

Klyne DM, Barbe MF, Hodges PW. Systemic inflammatory profiles and their relationships with
demographic, behavioral and clinical features in acute low back pain. Brain Behav Immun. 2017
Feb;60:84-92.

Queiroz BZ, Pereira DS, Rosa NMB, Lopes RA, Andrade AGP, Felício DC, Jardim RMFVS, Leopoldino
AAO, Silva JP, Pereira LSM. Inflammatory Mediators and Pain in the First Year After Acute
Episode of Low-Back Pain in Elderly Women: Longitudinal Data from Back Complaints in the
Elders-Brazil. Am J Phys Med Rehabil. 2017 Aug;96(8):535-540.

 

Do you feel stiff or experience aches and pain?

If you do, you have increased free radical damage and low-grade inflammation which is getting more and more common as we get older.

When free radicals damage tissue, inflammation is triggered. This type of inflammation spreads throughout the body and can be measured in the blood.

Not only can this create discomfort, but science recognizes this type of inflammation as a risk factor for cardiovascular disease and other chronic conditions.

That’s the reason the Curcumin-4 was developed.

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