Insulin resistance is getting more and more common and can lead to type 2 diabetes if nothing is done to interfere.
The following research include a systematic review of randomized controlled trials of the efficacy of resveratrol in the treatments of type 2 diabetes (Zhang T, et.al., 2021).
896 patients were included in the study, and the results showed improved insulin resistance, lower fasting blood glucose and insulin levels, and improved oxidative stress.
Non-alcoholic fatty liver disease is also a major health problem now. In this double-blind, randomized, placebo-controlled trial, the participants were either given 300 mg of resveratrol twice daily for 3 months or placebo capsules (Chen S, et.al. 2015).
The results showed that the group treated with resveratrol had significantly decreased liver enzymes, glucose, LDL cholesterol and TNF-alpha an inflammatory marker, in addition to other beneficial changes.
Chen S, Zhao X, Ran L, Wan J, Wang X, Qin Y, Shu F, Gao Y, Yuan L, Zhang Q, Mi M. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial. Dig Liver Dis. 2015 Mar;47(3):226-32.
Zhang T, He Q, Liu Y, Chen Z, Hu H. Efficacy and Safety of Resveratrol Supplements on Blood Lipid and Blood Glucose Control in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2021 Aug 24;2021:5644171.