Let’s face it — memory isn’t what it used to be once we hit our 60s. But what if a simple natural supplement could give your brain a lift?

A new study says yes, and the answer might already be in your fruit bowl.

The Study at a Glance

Researchers tested a special extract made from grape and blueberry polyphenols — plant compounds known for their antioxidant power.
This wasn’t a fly‑by‑night test either. It was a 6‑month, double‑blind, placebo‑controlled trial involving 215 healthy adults aged 60–70 (Bensalem J, et.al., 2019).

Here’s What They Did

Participants took either:

  • 600 mg/day of grape & blueberry extract (PEGB), or
  • A placebo

Researchers measured memory with tools like:

  • CANTAB PAL (a visuospatial memory test)
  • Verbal Recognition Memory (VRM)
  • Working memory tasks

The Big Reveal

Across the whole group, the extract didn’t change much.
But here’s where it gets interesting:

In the people with lower memory scores at the start, the extract made a real difference.

  • Verbal recall improved
  • Delayed memory recognition improved
  • Urine tests showed memory‑linked flavonoid metabolites — suggesting their bodies actually used the extract’s compounds

What This Means for You

If you’re:

  • Over 60
  • Starting to forget names or misplace keys more often
  • Eating a diet low in fruits high in polyphenols

…you might benefit the most from a polyphenol‑rich supplement.

Recommended Supplement: Polyphenol Nutrients

For broad‑spectrum nutritional support and advanced cellular protection, consider Pure Encapsulations Polyphenol Nutrients — a multivitamin/mineral formula enriched with blueberry, grape seed, pomegranate, green tea, quercetin, lutein, zeaxanthin, and more.

Why it stands out

  • Enhanced antioxidant and cell‑health support
  • Supports macular, cognitive, skin, heart, nerve and liver health
  • Choline & inositol for comprehensive B‑complex backing
  • Made with high‑quality, science‑backed ingredients

Exclusive offer: Register through this Pure Encapsulations Patient Direct link to receive 5 % off and free shipping on every order.

Takeaway

Grapes and blueberries aren’t just tasty — they may help protect your memory, especially if you’ve already noticed a little mental fog creeping in.

Before you run to the supplement aisle, remember: quality matters. Look for products that contain at least 258 mg of flavonoids per dose, like in the study.

Want to future‑proof your brain? Maybe it’s time to make grapes and blueberries your new daily habit.

Reference

Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, Dubreuil S, Paradis ME, Pomerleau S, Capuron L, Hudon C, Layé S, Desjardins Y, Pallet V. Polyphenols From Grape and Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study. J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):996-1007. doi: 10.1093/gerona/gly166. PMID: 30032176.

  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2025-07-21
  • Comments: 0
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