How Supplements Could Help Older Adults Fight Cognitive Decline

Cognitive decline is a concern for many as they age, especially for those at risk of dementia, mild cognitive impairment (MCI), or Alzheimer’s disease (AD). A recent systematic review (Fu Q, et.al., 2024) sheds light on the role of micronutrients in maintaining brain health and slowing cognitive decline in adults aged 65 and older. Here’s a simple breakdown of what the research reveals.

The Study at a Glance

The researchers analyzed 33 studies from the past two decades to understand how supplements might impact cognitive health. They looked specifically at how different vitamins and nutrients affected older adults with varying levels of cognitive function, from normal cognition to Alzheimer’s. The studies followed strict guidelines (like PRISMA) to ensure reliable results.

The Winners: Vitamin D, Probiotics, and Omega-3s

The review highlights three key players that stood out for their effectiveness:

  1. Vitamin D: Essential for brain health and linked to reduced cognitive decline.

  2. Probiotics: These gut-friendly bacteria may influence brain function through the gut-brain connection.

  3. Omega-3 Fatty Acids (PUFAs): Known for their anti-inflammatory properties, omega-3s seem to support brain function and protect against dementia.

The Mixed Results: Vitamin B

Vitamin B showed promise, but only in specific cases. For example, it worked better for non-aspirin users who had high levels of omega-3s in their blood. This suggests that some nutrients may work better when paired with others—or under certain conditions.

The Losers: Vitamins A, C, and E

Unlike the heavy hitters above, vitamins A, C, and E showed little to no significant effect on preventing cognitive decline or dementia.

Key Takeaways for Older Adults

  1. Focus on What Works: Supplements like vitamin D, probiotics, and omega-3s might provide the most benefit for brain health.

  2. Personalization Matters: Some effects depend on your unique biology, lifestyle, and even whether you take other medications like aspirin.

  3. Whole Health Approach: Supplements are not magic bullets. A healthy diet, regular exercise, and staying socially engaged are still crucial for cognitive health.

Explore Our Brain Health Supplements

Support your cognitive health with our curated selection of supplements:

  • Better Fish Oil: Rich in omega-3 fatty acids to help reduce inflammation and support brain function.
  • Vitamin D3: A key nutrient for maintaining brain health and reducing cognitive decline.
  • Vitamin B Complex: An effective blend of B vitamins to support optimal brain function under the right conditions.

Final Thoughts

A low glycemic, high nutrient, plant-based diet, regular exercise, and certain supplements can help reduce your risk for dementia and is worthwhile implementing.

Reference

Fu Q, DeJager J, Gardner EM. Supplementation and Mitigating Cognitive Decline in Older Adults With or Without Mild Cognitive Impairment or Dementia: A Systematic Review. Nutrients. 2024 Oct 21;16(20):3567.

  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2025-01-21
  • Comments: 0
Leave a comment