Vascular endothelium function tend to decline as we get older unless we have a healthy lifestyle and eat a certain way. The endothelium is the inner layer of the blood vessels. Research has shown that the severity of endothelial dysfunction relates to cardiovascular disease (Widlansky ME, et al. 2003). Is there really an easy way to improve that? Yes, there is and I will get into that in a moment, I just want to explain some few things that affects the function of the endothelium. Endothelial dysfunction is associated with increased oxidative stress, an important promoter of inflammatory processes (Lerman A, Zeiher AM, 2005). For that reason a dysfunctional endothelium may contribute to plaque destabilization and plaque erosion because of its reduced anti-inflammatory and anti-oxidative potential. If you could reduce oxidative stress and inflammation, you could also improve endothelial function which means you would improve the function of your blood vessels. This research is interesting. Flow-mediated dilation which is an indicator of endothelial function were measured in a group of postmenopausal women. They were then put into either a control group, a moderate aerobic exercise group or a group taking curcumin for 8 weeks before retested again (Akasawa N, et al. 2012). Flow-mediated dilatation increased significantly and also equally in both the exercise group and the group taking curcumin, but no changes were observed in the control group. Since curcumin has shown to reduce both inflammation and oxidative stress, it would make sense that endothelial function would improve. The best solution would of course be to both exercise and take a well absorbed form of curcumin.
Akazawa N1, Choi Y, Miyaki A, Tanabe Y, Sugawara J, Ajisaka R, Maeda S. Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. Nutr Res. 2012 Oct;32(10):795-9. doi: 10.1016/j.nutres.2012.09.002. Epub 2012 Oct 15.
Amir Lerman, MD;Andreas M. Zeiher, MD Contemporary Reviews in Cardiovascular Medicine Endothelial Function Cardiac Events
Widlansky ME1, Gokce N, Keaney JF Jr, Vita JA. The clinical implications of endothelial dysfunction. J Am Coll Cardiol. 2003 Oct 1;42(7):1149-60.

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  • Category: News
  • Author: Didrik Sopler
  • Published: 2020-03-28
  • Comments: 0
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