Curcumin EX

Do you feel stiff or experience aches and pain?

If you do, you have increased free radical damage and low-grade inflammation which is getting more and more common as we get older.

When free radicals damage tissue, inflammation is triggered. This type of inflammation spreads throughout the body and can be measured in the blood.

Not only can this create discomfort, but science recognizes this type of inflammation as a risk factor for cardiovascular disease and other chronic conditions.

Curcumin EX is a good formula if you have issues like this.

Below you will find references to some of the research on curcumin, that way you can see some of the results science has documented.

Research has shown that curcumin reduces several inflammatory cytokines (inflammatory substances).

Studies have shown that curcumin reduces several inflammatory cytokines (inflammatory substances), these are some examples IL-1beta, NF-kappaB, TNF-alpha and IL-6 (Panahi Y, et.al., 2016, Derosa G, et.al., 2016, Buhrmann C, et.al., 2011, Shakibaei M, et.al., 2007).

Curcumin EX contains an extensively studied curcumin extract, Meriva® that has 18 times higher bioavailability of curcumin and 29 times higher relative absorption of total curcuminoids vs. standardized curcumin.

References:

Buhrmann C, Mobasheri A, Busch F, Aldinger C, Stahlmann R, Montaseri A, Shakibaei M. Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem. 2011 Aug 12;286(32):28556-66.

Derosa G, Maffioli P, Simental-Mendía LE, Bo S, Sahebkar A.Effect of curcumin on circulating interleukin6 concentrations: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2016 Sep;111:394-404.

Panahi Y, Hosseini MS, Khalili N, Naimi E, Simental-MendíaLE, Majeed M, Sahebkar A. Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial. Biomed Pharmacother. 2016 Aug;82:578-82.

Shakibaei M, John T, Schulze-Tanzil G, Lehmann I, MobasheriA. Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis. BiochemPharmacol. 2007 May 1;73(9):1434-45.