Women are especially prone to bone loss after menopause, but men can also develop osteoporosis. The reviewed research investigated bone loss in men with metabolic syndrome (Ornstrup MJ, et al. 2014). The metabolic syndrome is associated with increased low grade inflammation and an increased risk for osteoporosis. The participants were given a daily dose of either 1000 mg of Resveratrol, 150 mg of Resveratrol or a placebo for 16 weeks. Assessments were done for changes in bone turnover markers and bone mineral density. It was found that Resveratrol had a dose dependent, positive effect on bone by stimulating bone formation or mineralization. The higher dose of Resveratrol showed a significant change. Because there are now ways to increase the bio-availability of Resveratrol, you don't necessarily have to take such a high dose.
Resveratrol is found in the skin of grapes, but also in other various plants.
It is known as an antioxidant.
Resveratrol was found to stimulate SIRT-1, one of the longevity genes.
Some of the other changes also include improved insulin sensitivity, increased number of
mitochondria (the energy producing entity of the cell) and improved motor function (they moved better).