The reason for this research was to determine the relationship between body fat mass and fat-free mass to the risk of mortality (Sedlmeier AM, et al., 2021).

Data from 7 studies were used including 16,155 individuals. Body composition was measured by bioelectrical impedance analysis and the researchers adjusted for several risk factors. The average follow up period was 14 years.

After the results were in the researchers concluded that excess fat mass is related to increased mortality risk, whereas fat-free mass protects against risk of mortality.


Stay lean by eating a high nutrient, low glycemic index plant-based diet and exercise regularly.

You can also take berberine which has been found to reduce the body mass index (BMI) and waist circumference (Yang J, et al., 2012). In this study patients with the metabolic syndrome treated with berberine for 3 months showed a decrease in their BMI from 31.5 to 27.4.

A review of 10 studies showed that both BMI and waist circumference decreased in participants taking berberine (Xiong P, et al.,2020).


Anja M Sedlmeier, Sebastian E Baumeister, Andrea Webe, Beate Fischer, Barbara Thorand, Till Ittermann, Marcus Dörr, Stephan B Felix, Henry Völzke, Annette Peters, Michael F Leitzmann, Relation of body fat mass and fat-free mass to total mortality: results from 7 prospective cohort studies, Am J Clin Nutr. 2021 Mar 11;113(3):639-646.

Xiong P, Niu L, Talaei S, Kord-Varkaneh H, Clark CCT, Găman MA, Rahmani J, Dorosti M, Mousavi SM, Zarezadeh M, Taghizade-Bilondi H, Zhang J.The effect of berberine supplementation on obesity indices: A dose- response meta-analysis and systematic review of randomized controlled trials.Complement Ther Clin Pract. 2020 May;39:101113.

Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M.Berberine improves insulin sensitivity by inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic syndrome patients.Evid Based Complement Alternat Med. 2012;2012:363845



Glucose Metabolism Support

  • This formula contains Berberine and Green Tea and was designed to support a healthy glucose metabolism and the cardiovascular system.
  • Berberine also suppresses neuroinflammatory responses through activation of the AMP-activated protein kinase (Lu DY, et al., 2010).
  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2021-04-30
  • Comments: 0
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