This population-based study included 495 077 women and men with an average age of 56.6 years (Li ZH, et al., 2020).

The researchers wanted to find out if glucosamine would affect mortality. They evaluated all-cause mortality and mortality due to cardiovascular disease, cancer, respiratory and digestive disease. The average follow up time was 8,9 years. This is what they found.

Regular glucosamine supplementation was associated with lower mortality due to all causes, cancer, cardiovascular disease, respiratory and digestive diseases.


Glucosamine sulfate is well known for reducing joint pain from osteoarthritis. Two studies conducted over three years by different research groups documented that cartilage degeneration stopped in the treatment group taking glucosamine sulfate while the control group experienced further degeneration (Reginster JY, et al. 2002, Pavelka K, et al. 2002).



Zhi-Hao Li, Xiang Gao, Vincent Ch Chung, Wen-Fang Zhong, Qi Fu, Yue-Bin Lv, Zheng-He Wang, Dong Shen, Xi-Ru Zhang, Pei-Dong Zhang, Fu-Rong Li, Qing-Mei Huang, Qing Chen, Wei-Qi Song, Xian-Bo Wu, Xiao-Ming Shi, Virginia Byers Kraus, Xingfen Yang, Chen Mao, Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study, Ann Rheum Dis. 2020 Jun;79(6):829-836.

Pavelka K, Gatterova J, et al. Glucoseamine sulfate use and delay of progression of knee osteoarthritis. A 3-year, randomized, placebo-controlled, double-blind study. Arch Intern Med, 2002; 162:2113-23.

Reginster JY, et al. Long-term effects of glucoseamine sulfate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet. 2001:357:251-256.


The BMJ contains the original form of glucosamine sulfate used in most of the research.

The BMJ Formula is different from other formulas because it contains:

  • Calcium and other minerals scientifically demonstrated to support bone formation.
  • Minerals in a form the body can easily use (not all forms of minerals are equally effective).
  • The building blocks of cartilage, which supports collagen formation.
  • Natural substances to reduce inflammation without the side effects of anti-inflammatory drugs.
  • Vitamin B6: research shows that vitamin B6 and magnesium may help prevent kidney stones.
  • Vitamin D3 is important for your body to use calcium, and for many other functions.
  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2020-10-16
  • Comments: 0
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