We used to believe that inflammation was not a factor in osteoarthritis.
This has, however, been proven to be wrong.
Inflammation has a catabolic effect on cartilage(it causes cartilage damage).
Whatever we can do to reduce excessive inflammation would help to reduce the symptoms of osteoarthritis.
What you eat on a daily basis is very important, but even if you eat well, some extra help with lowering inflammation is still a good idea since inflammation tends to increase as we get older.
Curcumin, the active ingredient of turmeric, can be that help.
Research has shown that curcumin protects human chondrocytes (cartilage cells) from the catabolic actions of IL-1beta an inflammatory cytokine (Henrotin Y, et al. 2010).
It also provides protection against MMP-3 up-regulation.
MMp-3 is an enzyme causing degradation of cartilage.
An abnormal increase in the activity of MMP-3 can contribute to cartilage degeneration, while a normal activity will help to keep the cartilage healthy, only removing damaged cells.
It makes sense to take curcumin, there is only one problem.
Regular curcumin is not well absorbed, making it impractical to use.
That issue has now been resolved.
There are several ways to make curcumin better absorbed, but they are not all equally good.
One way is to combine it with a black pepper extract which inhibits a secondary detox pathway of the liver, so it stays in the body longer.
I don’t think that’s a good idea because it also makes everything else which is detoxified through that pathway stay in the body longer.
I think we should rather assist the body in it’s attempt to detoxify.
It makes more sense to use a product which is absorbed better by other means.
Henrotin Y1, Clutterbuck AL, Allaway D, Lodwig EM, Harris P, Mathy-Hartert M, Shakibaei M, Mobasheri A. Biological actions of curcumin on articular chondrocytes. Osteoarthritis Cartilage. 2010 Feb;18(2):141-9. doi: 10.1016/j.joca.2009.10.002. Epub 2009 Oct 8.
Research has documented the many benefits of curcumin (found in turmeric spice), but regular turmeric is hard to absorb. The type of curcumin in our formula improves the absorption 6.93 fold compared to regular curcumin (Anthony B, et al. 2008).