Research continues to show us how different areas and functions of the body are influenced and connected in ways we have not been aware of. The article by researchers at the Emory University School of Medicine reviewed here covers some of these interesting connections (Haroon E, et al. 2012).

Elevated biomarkers of inflammation, including inflammatory cytokines and what is called acute-phase proteins, have been found in depressed patients. Administration of inflammatory stimuli has also been associated with the development of depressive symptoms. It has been demonstrated that inflammatory cytokines can interact with multiple pathways known to be involved in the development of depression. In other words, inflammatory cytokines can interact with neurocircuits relevant to mood regulation.

This is very interesting because what is called low grade systemic inflammation is quite common. Low grade inflammation is the type of inflammation you usually are not aware of since you don’t have to experience arthritis or a hot swollen joint for this to occur. Inflammation is a risk factor for cardiovascular disease and it can also affect your mood according to research. How we feel psychologically can slowly change, you may not even realize that you used to be happier.

Three of the things the researchers in this article say contribute to inflammation and can serve as a focus for preventable strategies related to depression are diet, obesity and leaky gut. These three things are all related to what you eat.

An easy and quick way to start to incorporate foods that will help you lose weight and decrease inflammation is to download Learn to Eat.


Haroon E, Raison CL, Miller AH. Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. Neuropsychopharmacology. 2012 Jan;37(1):137-62. doi: 10.1038/npp.2011.205. Epub 2011 Sep 14.
  • Category: News
  • Author: Didrik Sopler
  • Published: 2020-03-28
  • Comments: 0
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