The purpose of this study was to assess the association of habitual glucosamine use with risk of cardiovascular disease events (Ma H, et.al., 2019).
466039 participants were followed for a median follow-up of seven years. The cardiovascular events included cardiovascular death, coronary heart disease, and stroke.
After adjustment for age, sex, body mass index, race, lifestyle factors, dietary intakes, drug use, and other supplement use, glucosamine use was associated with a significantly lower risk of cardiovascular death, coronary heart disease, and stroke.
The researchers concluded that habitual use of glucosamine supplements to relieve osteoarthritis pain might also be related to lower risks of cardiovascular events.
It’s recommended to use glucosamine sulfate since that has been researched the most for osteoarthritis benefits.
Hao Ma, Xiang Li, Dianjianyi Sun, Tao Zhou, Sylvia H Ley, Jeanette Gustat, Yoriko Heianza, Lu Qi. Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank. BMJ. 2019 May 14;365:l1628.