Can glucose levels within the normal range be harmful?

The participants of this study were 266 cognitively healthy individuals without type 2 diabetes, 60-64 years of age (Cherbuin N, et al., 2012).

MRI scans of their brains were recorded at the beginning of the study and 4 years later.

Plasma glucose levels were found to be significantly associated with atrophy of the hippocampus and the amygdala areas of the brain. 6%-10% reduction in volume was detected after controlling for age, sex, body mass index, hypertension, alcohol, and smoking.

High plasma glucose levels within the normal range were associated with greater atrophy of structures relevant to aging and neurodegenerative processes.

There are several things which can affect blood glucose levels.

The nutrient content and glycemic index of the food we eat are very important. How much sleep and the quality of the sleep we get is especially important, but stress and physical activity will also affect the blood glucose levels.

In addition to that, taking berberine which is a plant substance can be an easy way to reduce blood glucose (Yin J, et al., 2008).

References

Nicolas Cherbuin 1, Perminder Sachdev, Kaarin J Anstey, Higher normal fasting plasma glucose is associated with hippocampal atrophy: The PATH Study, Neurology. 2012 Sep 4;79(10):1019-26.

Yin J, Xing H, Ye J.Efficacy of berberine in patients with type 2 diabetes mellitus.Metabolism. 2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013.

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