C-reactive protein (CRP) is an inflammatory marker. The test for highly sensitive C-reactive protein is also a test used to evaluate the risk for cardiovascular disease.

In the following study the researchers investigated magnesium’s effect on CRP (Mazidi M, et.al., 2018), 8 studies were analyzed, and the results showed that magnesium supplementation significantly reduced serum CRP level.


In this study the researchers evaluated the effect of supplementation with magnesium on serum CRP levels (Simental-Mendia LE, et.al, 2017). The research accessed data from 11 studies.

They found that magnesium supplementation reduced CRP levels among individuals with inflammation CRP levels of more than 3 mg/dL.


Mazidi M, Rezaie P, Banach M. Effect of magnesium supplements on serum C-reactive protein: a systematic review and meta-analysis. Arch Med Sci. 2018 Jun;14(4):707-716.

Simental-Mendia LE, Sahebkar A, Rodriguez-Moran M, Zambrano-Galvan G, Guerrero-Romero F. Effect of Magnesium Supplementation on Plasma C-reactive Protein Concentrations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Curr Pharm Des. 2017;23(31):4678-4686.


  • The BMJ contains a high amount of very bioavailable magnesium.
  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2021-09-17
  • Comments: 0
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