Osteoarthritis is a very common condition, and we don’t have to be very old before we can detect signs of cartilage degeneration.

Hip and knee osteoarthritis is considered one of the leading causes of disability (Cross M, et al. 2014).

In addition to inflammation, which is probably the first thing you are thinking about when you hear the word arthritis, free radical damage is also involved.

According to this study, participants with osteoarthritis and a control group were measured for lipid peroxidation products to assess oxidative stress, indicating free radical damage (Surapaneni KM, Venkataramana G, 2007).

Moreover, glutathione, ascorbic acid, vitamin E and activities of antioxidant enzymes were also measured.

The results suggested higher free radical production with increased lipid peroxidation products, lower levels of glutathione, ascorbic acid and vitamin E among other things, in the group with osteoarthritis.

Glutathione is a very powerful antioxidant the body is making, but it makes less as we get older, and we actually need more.

Glutathione can be a very effective way of reducing free radical damage.

Therefore, Glutathione needs to get into the cells. Hence, you can now supplement with S-Acetyl Glutathione. It is the only available form of glutathione that gets into the cells where it is needed.


Cross M1, Smith E1, Hoy D2, Nolte S3, Ackerman I4, Fransen M5, Bridgett L5, Williams S6, Guillemin F7, Hill CL8, Laslett LL9, Jones G9, Cicuttini F10, Osborne R11, Vos T12, Buchbinder R13, Woolf A14, March L1. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014 Jul;73(7):1323-30. doi: 10.1136/annrheumdis-2013-204763. Epub 2014 Feb 19.

Surapaneni KM1, Venkataramana G. Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in patients with osteoarthritis. Indian J Med Sci. 2007 Jan;61(1):9-14.

Effective S-Acetyl Glutathione

Protect yourself

Glutathione is your primary defense against aging, but regular glutathione is oxidized (destroyed in the stomach) and provides little value. S-Acetyl Glutathione is easily absorbed and provides protection and may also help reduce the risk of dementia. It is also the only form of glutathione shown to get into the cells where it is needed.


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  • Category: News
  • Author: Didrik Sopler
  • Published: 2020-03-28
  • Comments: 0
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