Resveratrol and Neurodegenerative Disorders

Neurodegenerative diseases, characterized by neuronal loss, are rising. Recent evidence highlights the potential involvement of inflammation, oxidative stress, autophagy, and apoptosis (Pourhanifeh MH, et.al., 2019).

Autophagy is the process where degradation of the cell removes unnecessary or dysfunctional components of the cell. Apoptosis is the process of programed cell death.

The health-boosting polyphenol, resveratrol, has shown promising therapeutic effects on cell dysfunction leading to neurodegenerative dysfunction.

Resveratrol may reduce cell damage caused by inflammation and influence vital cellular processes such as autophagy and apoptosis under stress. A review of studies published until early 2019, supports the beneficial impact of resveratrol on the treatment of neurodegenerative disorders.

Reference Link: https://pubmed.ncbi.nlm.nih.gov/31333112/

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Mohammad H Pourhanifeh 1, Rana Shafabakhsh 1, Russel J Reiter 2, Zatollah Asemi 1. The Effect of Resveratrol on Neurodegenerative Disorders: Possible Protective Actions Against Autophagy, Apoptosis, Inflammation and Oxidative Stress. Curr Pharm Des. 2019;25(19):2178-2191.