Alzheimer’s disease is at least partially caused by decreased clearance of the beta-amyloid peptide breakdown products.  The reviewed research investigated how different diets may affect the removal of these breakdown products (Hanson AJ,et al. 2013).

One group of the participants were older adults with normal cognition, while the other group were older adults with mild cognitive impairment. Two types of diets were tested. One was high in saturated fat and had a high glycemic index (included high glycemic index carbohydrates). The other diet was low in saturated fat and had a low glycemic index.

The results showed that the low saturated fat, low glycemic index diet decreased the levels of the lipoproteins that were less effective at clearing the beta-amyloid while the high saturated fat, high glycemic index diet increased these lipoproteins. This is very good news because this showed that you can reduce the risk for Alzheimer’s disease by implementing a low glycemic index diet low in saturated fat. This type of diet also helps to reduce the risk for other chronic diseases because it helps to reduce inflammation.

If you want to know more about this, both of the books “Effective Nutrition for Effective Healing” and “The Food Connection” will show you how to implement a very low glycemic index, high nutrient way of eating.



Hanson AJ, Bayer-Carter JL, Green PS, Montine TJ, Wilkinson CW, Baker LD, Watson GS, Bonner LM, Callaghan M, Leverenz JB, Tsai E, Postupna N, Zhang J, Lampe J, Craft S. Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides: Randomized Clinical Trial. JAMA Neurol. 2013 Jun 17:1-9. doi: 10.1001/jamaneurol.2013.396. [Epub ahead of print]
  • Category: News
  • Author: Didrik Sopler
  • Published: 2020-03-28
  • Comments: 0
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