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As you have seen, even osteoarthritis involves inflammation; and also free radical damage to cartilage.
Glucosamine sulfate can reduce inflammation a little bit (Largo R, et al. 2003). To further reduce inflammation you can use curcumin (Ren J, Sowers JR, 2014, Gupta SC, et al. 2013). Regular curcumin is not well absorbed so you need to be sure you use a formula with a raw material that has shown to improve the absorption.
Omega 3 fatty acids from fish oil has a lot of research behind it showing it’s ability to reduce inflammation by inhibiting several common inflammatory cytokines(Adam O, 2003). For that reason it makes sense to take a high quality fish oil with high amounts of EPA and DHA( the active ingredients in omega 3 fat).
To further protect the tissue from free radical damage, you can take S-Acetyl Glutathione. Glutathione is a highly effective antioxidant the body is producing, but we make less of it as we get older. We usually start to experience some stiffness when we reach a certain age. You should feel a decrease in stiffness when you take enough of this supplement.
Better Fish Oil
The Better Fish Oil comes in the form of triglycerides which offers better stability to the fatty acids and prevents breakdown and oxidation. Most fish oils on the market are ethyl esters because that’s cheaper to produce. Fish oil in a triglyceride form is also better absorbed than ethyl esters (Beckerman B. et al. 1990).
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Effective S-Acetyl Glutathione
Glutathione is your primary defense against aging, but regular glutathione is oxidized (destroyed in the stomache) and provides little value. S-Acetyl Glutathione is easily absorbed and provides protection. Glutathione is a very effective antioxidant, the body makes to protect itself from free radical damage (oxidative stress). It can help repair cells that are damaged by stress, radiation, pollution, infection, and other illnesses.
Better Curcumin
Research has documented the many benefits of curcumin (found in turmeric spice), but regular curcumin is hard to absorb. Our formula improves the intake of this beneficial substance into the cells.
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Adam O1. Dietary fatty acids and immune reactions in synovial tissue. Eur J Med Res. 2003 Aug 20;8(8):381-7.
Gupta SC1, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013 Jan;15(1):195-218. doi: 10.1208/s12248-012-9432-8. Epub 2012 Nov 10.
Largo R1, Alvarez-Soria MA, Díez-Ortego I, Calvo E, Sánchez-Pernaute O, Egido J, Herrero-Beaumont G. Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytes. Osteoarthritis Cartilage. 2003 Apr;11(4):290-8.
Ren J1, Sowers JR2. Application of a novel curcumin analog in the management of diabetic cardiomyopathy. Diabetes. 2014 Oct;63(10):3166-8. doi: 10.2337/db14-0863.
