Magnesium is usually not what we think of when it comes to joint health and osteoarthritis. Magnesium is, however, also affecting the health of your joints. Research indicates that magnesium affects several pathways that have been implicated in osteoarthritis, including inflammatory mediators, cartilage damage, and defective chondrocyte biosynthesis, among other things (Li Y, et al. 2016). In one study including 2,855 participants, serum magnesium concentration was measured and radiographic osteoarthritic changes were evaluated (Zeng C., et al. 2015). The results showed a significant association between serum magnesium levels and osteoarthritis. The participants with higher magnesium levels had less osteoarthritis. Magnesium is involved in 300 enzymatic reactions in the body and even affects the health of your joints. Just remember that it is better to take magnesium with other important minerals since minerals tend to affect each other. If you only take one mineral at a time, you may decrease the level of another one. Something else to keep in mind is that the minerals zinc, copper and manganese are also important to keep your cartilage healthy. To avoid gastrointestinal irritation and improve the absorption, magnesium in the form of an amino acid chelate is the preference.
Li Y1, Yue J1, Yang C2. Unraveling the role of Mg(++) in osteoarthritis. Life Sci. 2016 Feb 15;147:24-9. doi: 10.1016/j.lfs.2016.01.029. Epub 2016 Jan 19.
Zeng C1, Wei J1, Li H1, Yang T1, Zhang FJ1, Pan D1, Xiao YB1, Yang TB1, Lei GH2. Relationship between Serum Magnesium Concentration and Radiographic Knee Osteoarthritis. J Rheumatol. 2015 Jul;42(7):1231-6. doi: 10.3899/jrheum.141414. Epub 2015 Jun 1.
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