As more and more people live longer neurological problems are getting more and more common.

There are however things you can do to help protect yourself. The earlier you start the better it is since prevention is always easier than treating a neurological problem.

Berberine is an interesting plant compound which has been documented to produce a variety of beneficial effects. The following are benefits that affects the nervous system.


Laboratory research has shown potent neuroprotective effects of berberine (Song D, et al., 2020).

This article writes about the neuroprotective effects of berberine and more specifically the protective effects berberine has on the mitochondria, the energy producing entity of the cell (Zhao C, et al., 2019).

Berberine was found to significantly activate AMPK signaling pathways involved in anti-neuroinflammation (Lu DY, et al., 2010). AMPK is an enzyme that plays a key role as a regulator of the cellular energy balance.

Berberine also effectively inhibited the expression of proinflammatory cytokines such as TNF-alpha, IL-1beta, and IL-6.

Taking berberine regularly is an easy way to receive many health benefits.



Lu DY, Tang CH, Chen YH, Wei IH. Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia. J Cell Biochem. 2010 Jun 1;110(3):697-705.

Song D, Hao J, Fan D. Biological properties, and clinical applications of berberine. Front Med. 2020 Oct;14(5):564-582.

Zhao C, Su P, Lv C, Guo L, Cao G, Qin C, Zhang W. Berberine Alleviates Amyloid β-Induced Mitochondrial Dysfunction and Synaptic Loss. Oxid Med Cell Longev. 2019.


  • Category: News
  • Author: Didrik Sopler, Ph.D., L.Ac.
  • Published: 2021-02-26
  • Comments: 0
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