This research included 155 women 65 years or older with acute low back pain (Queiroz BZ, et.al., 2017).
The researchers showed a relationship between inflammation and low back pain, establishing that low IL-6 levels (an inflammatory marker) preceded the recovery. This supports that proinflammatory cytokines promote pain.
In the first year after an acute episode of low back pain, there was a decrease in the severity of low back pain corresponding to decreased levels of IL-6 and TNF-α, another inflammatory marker.
The researcher concluded that the probability of occurrence of pain relief at the 12-month
follow-up was 2.22 times higher in elderly women who had low levels of IL-6.
Systemic inflammation is linked with the development and persistence of many pathological pain states (Klyne DM, et.al., 2017).
Both CRP, an inflammatory marker, and IL-6 were higher in study participants with acute low back pain compared with controls, and they were also higher in the participants with more pain compared with those who had less pain?
The researchers said these findings suggest systemic CRP and IL-6 are important contributors to
inflammation in the early phase of low back pain and that various factors can shape these responses.
A plant-based low glycemic index diet can be very effective in reducing systemic inflammation.
Research has also shown plant-derived compounds in supplemental form to reduce free radicals and inflammation.
Klyne DM, Barbe MF, Hodges PW. Systemic inflammatory profiles and their relationships with
demographic, behavioral and clinical features in acute low back pain. Brain Behav Immun. 2017
Queiroz BZ, Pereira DS, Rosa NMB, Lopes RA, Andrade AGP, Felício DC, Jardim RMFVS, Leopoldino
AAO, Silva JP, Pereira LSM. Inflammatory Mediators and Pain in the First Year After Acute
Episode of Low-Back Pain in Elderly Women: Longitudinal Data from Back Complaints in the
Elders-Brazil. Am J Phys Med Rehabil. 2017 Aug;96(8):535-540.
Do you feel stiff or experience aches and pain?
If you do, you have increased free radical damage and low-grade inflammation which is getting more and more common as we get older.
When free radicals damage tissue, inflammation is triggered. This type of inflammation spreads throughout the body and can be measured in the blood.
Not only can this create discomfort, but science recognizes this type of inflammation as a risk factor for cardiovascular disease and other chronic conditions.
That’s the reason the Curcumin-4 was developed.
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