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General Health

Low brain derived neurotrophic factor linked to decreased memory. This is one way to increase it.

Posted by on 9:00 am General Health | 0 comments

BDNF

 

The reduction of brain-derived neurotrophic factor (BDNF) has been shown to affect cognitive
function, learning, and memory and also causes behavioral disorders.
There are however several ways to increase BDNF.
The following research reviewed several studies which investigated the effect of curcumin on
BDNF (Sarraf P, et.al., 2019).
The supplemented dose of curcumin the participants took ranged from 200 to 1820 mg per day,
and the studies lasted from 8 to 12 weeks,
The researchers found that curcumin significantly increased BDNF levels.

 

 

Curcumin is not well absorbed unless it has been manufactured to improve absorption. In this
research the dose varied quite a bit in the different studies which were included.
If you take a curcumin formula shown to be better absorbed, you don’t have to take a very high
dose. It is for that reason a very easy way to increase BDNF levels.

 

curcumin

 

Reference:
Sarraf P, Parohan M, Javanbakht MH, Ranji-Burachaloo S, Djalali M. Short-term curcumin
supplementation enhances serum brain-derived neurotrophic factor in adult men and women: a
a systematic review and dose-response meta-analysis of randomized controlled trials. Nutr Res.
2019 May 9;69:1-8.

Better Curcumin

  • We added boron to provide even more benefits. There is no other formula like this.
  • Curcumin is a good antioxidant, but it is especially effective in helping to reduce inflammation. For these reasons, curcumin provides many health benefits.
  • The raw material used in the Better Curcumin formula is the only form of curcumin shown to pass through the blood-brain barrier and improve memory
  • This study also showed a significant reduction in both total cholesterol and LDL cholesterol, the so-called bad cholesterol.
  • The following research shows that this form of curcumin is 65 times more bioavailable than regular curcumin

What type of exercise improves memory the most?

Posted by on 9:00 am Exercise, General Health, Intensity Training | 0 comments

older people exercising

 

Exercise, in general, is beneficial for the brain, but is one type of exercise more beneficial for
memory? That’s what the following research investigated.
Sixty-four sedentary older adults either did high-intensity interval training, moderate continuous
training or stretching as a control (Kovacevic A, et.al., 2019).
The researchers found that high-intensity interval training resulted in the greatest
memory performance in inactive older adults compared to moderate continuous training
or stretching.

 

 

They also found that improvement in fitness correlated with improvement in memory
performance since moderate exercise also helped.
Brain-derived neurotrophic factor (BDNF) which is a protein plays an important role in the
survival and growth of the nervous system. This means that BDNF is important for keeping the
brain healthy.

 

older man stretching

 

This research tested the effectiveness of two high-intensity exercise protocols, both known to
improve cardiovascular health, to determine whether they have similar efficacy in affecting
BDNF levels ( Saucedo Marquez CM , et.al., 2015).
Participants performed a continuous exercise protocol at 70% of maximal work rate and a
high-intensity interval training protocol at 90% of maximal work rate for periods of 1 minute
alternating with 1 min of rest (both protocols lasted 20 min).
Both protocols increased BDNF levels, but the high-intensity interval training improved
BDNF levels the most.

References:

Kovacevic A, Fenesi B, Paolucci E, Heisz JJ. The effects of aerobic exercise intensity on
memory in older adults. Appl Physiol Nutr Metab. 2019 Oct 30.
Saucedo Marquez CM, Vanaudenaerde B, Troosters T, Wenderoth N. High-intensity interval
training evokes larger serum BDNF levels compared with intense continuous exercise. J Appl
Physiol (1985). 2015 Dec 15;119(12):1363-73

Is a high protein weight loss diet the best approach if you want to lose weight?

Posted by on 9:00 am Body fat, Body mass index, Calories, Diet, Fat, General Health, Get in shape, Lose fat, Stay healthy, Weight, Weight loss, Women, Womens health | 0 comments

Is a high protein weight loss diet the best approach if you want to lose weight?

 

 

pretty girl holding a tray with high protein food

 

In this study, two diets containing different amounts of protein were compared (Smith GI, et al., 2016).

The participants, obese postmenopausal women lost 10% weight using a diet providing either 0.8 g of protein per kg of body weight or a diet providing 1.2 g of protein per kg of body weight.

 

Weight loss usually results in several metabolic benefits, one is improved insulin sensitivity, which means that the transfer of blood glucose into the cells is improved.

 

 

The researchers found that when compared to the low protein diet, the high protein diet prevented the weight loss-induced improvements in muscle insulin signaling and insulin-stimulated glucose uptake.

Not only that but induced adaptations in oxidative stress and cell structural biology pathways, which also are benefits accompanying weight loss, did not take place on the high protein diet.

 

One of the benefits of the high protein diet was that it reduced the weight loss induced a decline in lean tissue mass by 45%.

You don’t want to lose lean muscle mass, but that can be prevented by including exercises, which any good weight loss program will recommend.

 

There are many ways to lose weight, but not all approaches give you the same benefits, so choose wisely.

 

a table with high protein food

 

References:

Smith GI, Yoshino J, Kelly SC, Reeds DN, Okunade A, Patterson BW, Klein S, Mittendorfer B, High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women.Cell Rep. 2016 Oct 11;17(3):849-861.

How long does it take to reduce cardiovascular risk by changing what you eat?

Posted by on 9:00 am Blood Pressure, Cholesterol, Diet, Eating, General Health, Health, Health Risk, Research, Stay healthy | 0 comments

 

How long does it take to reduce cardiovascular risk by changing what you eat?

 

 

This research was conducted to investigate the effect on cardiovascular risk factors using only
food (McDougall J, et.al., 2014).
1615 people participated in this research.
The protocol was implemented for only 7 days, and measurements of weight, blood pressure,
blood sugar, and blood lipids were measured at the start of the study and 7 days later.
The participants consumed a low-fat (≤10% of calories), high-carbohydrate (~80% of calories),
plant-based diet.
Most antihypertensive and antihyperglycemic medications were reduced or discontinued at the
beginning of the study.

 

 

After 7 days the average weight loss was 1.4 kg, total cholesterol decreased by an
average of 29 mg/dl, systolic blood pressure decreased on average by 18 mm Hg,
diastolic blood pressure by an average of 10 mm Hg, and blood glucose by an average of
11 mg/dL.

 

 

This was implementing a plant-based vegan diet.
Most people think it will take quite a while to see changes in laboratory tests from dietary
changes, but as you can see, that is not the case at all. You just have to follow an effective
protocol.

Reference:

McDougall J1, Thomas LE, McDougall C, Moloney G, Saul B, Finnell JS, Richardson K,
Petersen KM. Effects of 7 days on an ad libitum low-fat vegan diet: the McDougall Program
cohort. Nutr J. 2014 Oct 14;13:99. doi: 10.1186/1475-2891-13-99.

What is TMAO, and why should you avoid it?

Posted by on 9:00 am Cardiovascular Disease, Diet, Diet, General Health, Health, Health Risk, Research | 0 comments

 

What is TMAO, and why should you avoid it?

 

The bacterial flora of the intestines convert choline into trimethylamine, which again is
converted into TMAO (trimethylamine-N-oxide) by the involvement of an enzyme from
the liver.

 

 

Choline is found in animal-derived products like eggs, dairy products, and meat.
The following study investigated the involvement of TMAO and major adverse cardiovascular
events (death, myocardial infarction, or stroke) during 3 years of follow-up in 4007 patients
(Tang WH, et.al., 2013).

 

 

The researchers found that increased plasma levels of TMAO were associated with an
increased risk of a major adverse cardiovascular event. An elevated TMAO level predicted an
increased risk of major adverse cardiovascular events after adjustment for traditional risk
factors, as well as in lower-risk subgroups.

 

 

In other words, TMAO is an additional cardiovascular risk factor many are not aware of.
This research documents that TMAO triggers inflammation and is involved in the process of
forming atherosclerosis (Seldin MM, et.al., 2016).
The bacterial flora of people eating animal-derived products is producing TMAO, vegans and
vegetarians don’t produce much, because they have a different bacterial flora of the intestinal
tract (Koeth RA, et.al., 2019).

 

References:

Koeth RA, Lam-Galvez BR, Kirsop J, Wang Z, Levison BS, Gu X, Copeland MF, Bartlett D,
Cody DB, Dai HJ, Culley MK, Li XS, Fu X, Wu Y, Li L, DiDonato JA, Tang WHW, Garcia-Garcia
JC, Hazen SL. l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in
humans. J Clin Invest. 2019 Jan 2;129(1):373-387.

Seldin MM, Meng Y, Qi H, Zhu W, Wang Z, Hazen SL, Lusis AJ, Shih DM. Trimethylamine
N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein
Kinase and Nuclear Factor-κB. J Am Heart Assoc. 2016 Feb 22;5(2). pii: e002767.

Senthong V, Li XS, Hudec T, Coughlin J, Wu Y, Levison B, Wang Z, Hazen SL, Tang
WH. Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite,
Is Associated With Atherosclerotic Burden. J Am Coll Cardiol. 2016 Jun 7;67(22):2620-8.

What works best to keep cardiovascular risk factors low, a high fat diet, a Mediterranean diet or a high carbohydrate low fat diet?

Posted by on 8:31 am Body fat, Diet, Eating, General Health, Health, Health Risk, The Learn to Eat Plan | 0 comments

 

 

What works best to keep cardiovascular risk factors low, a high-fat diet, a Mediterranean diet or a high carbohydrate low-fat diet?

 

Research has compared these different approaches a while back, and we have had the results for a while. The reason why they’re still are questions about the best approach is probably that there are many ways to lose weight, and especially a high-fat diet also called a ketogenic diet has been promoted as a solution to almost everything including weight loss.

What did the research show when it comes to cardiovascular risk?

The participants of this study completed each 4-week diet intervention with a 4 week washout period between each approach (Miller M, et.al., 2009).

 

 

Food records were analyzed, fasting blood samples, and brachial artery reactivity testing was performed. During the Mediterranean and the high carbohydrate, low-fat diets maintenance phase, there were significant reductions in low-density lipoprotein cholesterol (LDL).

For the Mediterranean diet the LDL decreased 11.8%, and for the high carbohydrate, low-fat diet the LDL decreased by 16.6%.

The LDL increased on the high-fat diet.

CRP, an inflammatory marker decreased the most on the high carbohydrate, low-fat diet and increased on the high-fat diet.

 

 

Brachial artery testing revealed an inverse correlation between flow-mediated vasodilatation and intake of saturated fat. This means decreased vasodilation with increased fat intake.

The science does not back up the promoted benefits of a high-fat diet.

According to the research, a high-fat diet increases cardiovascular risk.

It is, however, important to remember that not all carbohydrates are equal.

Avoid processed high glycemic index carbohydrates, and increase the intake of plant-based food.

 

 

Reference:

Miller M1, Beach V, Sorkin JD, Mangano C, Dobmeier C, Novacic D, Rhyne J, Vogel RA. Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance.J Am Diet Assoc. 2009 Apr;109(4):713-7.

Learn to eat program

  • How and why different foods affect you
  • How to put together meals that will produce the results you’re looking for
  • How to lose weight effortlessly by eating the foods your body needs
  • How to gain muscle and improve sports performance.
  • How to reduce inflammation and pain
  • How to stabilize your moods so you feel happier
  • How to lower cholesterol and triglycerides