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Help improve brain function and decrease inflammation with small amounts of this mineral.

Posted by on Brain, General Health, Health, Inflammation | 0 comments

The research on the mineral boron started many years ago, and the more it has been studied the more we realize how important this mineral is. It turns out that it is involved in a huge number of important functions (Pizzorno L, 2015).

The following article describes how low boron intake can affect brain function and cognitive performance (Penland JG, 1994).

 

When compared to high intake of boron, low boron intake resulted in significant poorer performance in several areas, some of were eye-hand coordination, attention, long and short-term memory.

 

In a double-blind, placebo-controlled study conducted on patients diagnosed

with osteoarthritis 2 common inflammatory markers, highly sensitive C-reactive protein (hs-CRP) and TNF-alpha decreased significantly after 1 week of boron supplementation (Naghil MR, et.al., 2011).

 

Boron supplementation has even showed benefits for rheumatoid arthritis.

After 60 days of supplementation with boron, a significant decrease in the inflammatory markers erythrocyte sedimentation rate, C-reactive protein (CRP), IL-1alpha, IL-6 and TNF-alpha were found (Hussain SA, et.al., 2016).

 

Symptoms were also improved.

 

References

Hussain SA, Abood SJ, Gorial FI. The adjuvant use of calcium fructoborate and borax with etanercept in patients with rheumatoid arthritis: Pilot study. J Intercult Ethnopharmacol. 2016 Dec 8;6(1):58-64.

Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MS. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. J Trace Elem Med Biol. 2011 Jan;25(1):54-8. Pizzorno L. Nothing Boring About Boron. ntegr Med (Encinitas). 2015 Aug;14(4):35-48.

Scorei R, Mitrut P, Petrisor I, Scorei I. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis. Biol Trace Elem Res. 2011 Dec;144(1-3):253-63.

 

 

 

Better Curcumin

 We added boron to provide even more benefits. There is no other formula like this.

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Is there a connection between Cardiovascular risk and the risk for Alzheimer’s disease?

Posted by on Alzheimer’s, Brain, Dementia, General Health | 0 comments

 

An increased risk for developing Alzheimer’s disease is linked to the presence of apoE4, a genetic factor, which is also strongly associated with developing atherosclerosis which increases the risk for Cardiovascular disease (Altman R, Rutledge JC, 2010).                                                                     

The authors of the same article state that cardiovascular risk factors, including elevated blood cholesterol and triglycerides, increase the likelihood of Alzheimer’s disease and vascular dementia.

 

Researchers have also found that atherosclerosis causing obstruction of arteries at the base of the brain was more extensive in a group with Alzheimer’s disease when compared with a control group without dementia (Roher AE, et.al., 2011).

 

Arterial stiffness, atherosclerosis, endothelial degeneration and dysfunction of the blood-brain barrier can induce several features of Alzheimer’s disease including atrophy of certain areas of the brain (Kalaria RN, et.al., 2012). The endothelium is the inner lining of the blood vessels.

 

 

There are also other risk factors for Alzheimer’s disease and dementia, I will write more about that later.

 

Making changes to the way you eat is the most effective way to reduce cardiovascular risk, and you would most likely also reduce your risk for Alzheimer’s disease and dementia at the same time.  

When we correct the reasons for chronic conditions, we see an improvement in many areas, since the same reasons are involved in most chronic conditions.

 

 

References

Altman R, Rutledge JC. The vascular contribution to Alzheimer’s disease. Clin Sci (Lond). 2010 Aug 5;119(10):407-21.

Kalaria RN, Akinyemi R, Ihara M. Does vascular pathology contribute to Alzheimer changes? J Neurol Sci. 2012 Nov 15;322(1-2):141-7.

Roher AE, Tyas SL, Maarouf CL, Daugs ID, Kokjohn TA, Emmerling MR, Garami Z, Belohlavek M, Sabbagh MN, Sue LI, Beach TG. Intracranial atherosclerosis as a contributing factor to Alzheimer’s disease dementia. Alzheimers Dement. 2011 Jul;7(4):436-44.

 

Learn to Eat Program

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  • A simple program that explains food that helps you lose weight and become healthy.
  • Fast, easy and delicious recipes…

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This Can Help Prevent Shrinkage Of Key Brain Areas

Posted by on Brain, General Health | 0 comments

 

Shrinkage of certain brain areas is linked to decreased cognitive function and Alzheimer’s disease.

The researchers used MRI scanning of the brain to verify the results, and the participants were elderly people with increased risk for dementia (Douaud G, et.al., 2013).

In an initial randomized study the researchers did, they showed that treatment with these B vitamins: Folic acid 800 mcg,  B6 20 mg, and B12 500 mcg, slowed shrinkage of the whole brain volume over 2 years.

 

In this study, they demonstrated that vitamin B treatment reduced grey matter atrophy (shrinkage) 7-fold in the areas specifically vulnerable to the Alzheimer’s process.

In the placebo group, higher levels of homocysteine were associated with faster grey matter atrophy, but this is largely prevented by the B vitamins Folic acid, B6, and B12.

 

 

Homocysteine is a metabolite and an amino acid involved I an important metabolic pathway. It is however not healthy to have high homocysteine levels.

An earlier study found that higher folate levels were associated with a better cognitive function, and better performance on psychomotor speed regardless of homocysteine levels (deLau LM, et.al.,2007).

The 1092 participants did not have dementia and were between 60 and 90 years of age. They underwent extensive cognitive testing and brain imaging.

When 51 patients with Alzheimer’s disease and 65 cognitively screened controls were studied, blood holotranscobalamin which is the active fraction of blood B12, were found to be low in the Alzheimer’s patients (Refsum H, Smith AD, 2003).

 

Blood levels of regular cobalamin (B12) were however not low.

When you take B vitamins, take a high-quality B-Complex which should include all of the B vitamins and the metabolite of folic acid methyltetrahydrofolate, to ensure that your body can use it. I also recommend methylcobalamin which is the form of B12 important for the nervous system.

 

 

 

 

References

de Lau LM, Refsum H, Smith AD, Johnston C, Breteler MM. Plasma folate concentration and cognitive performance: Rotterdam Scan Study. Am J Clin Nutr. 2007 Sep;86(3):728-34.

Douaud G, Refsum H, de Jager CA, Jacoby R, Nichols TE, Smith SM, Smith AD. Preventing Alzheimer’s disease-related gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9523-8.

Refsum H, Smith AD. Low vitamin B-12 status in confirmed Alzheimer’s disease as revealed by serum holotranscobalamin. J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):959-61.

 

Vitamin B Complex

The B1 (thiamine), B2 (riboflavin), B6 (pyridoxine), and B12 (cobalamin) comes in their physiologically active form, making them easier to absorb.

 

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How to Improve Your Brain Function

Posted by on Brain, Health, Inflammation | 0 comments

 

If you were going to focus on only 1 thing to improve your brain function, you should reduce inflammation.

When markers of low-grade inflammation and endothelial dysfunction were tested in participants between the age of 67 and 79, the study showed that both low-grade inflammation and endothelial dysfunction contributed to reduced information processing speed and executive function (Heringa SM, et.al., 2014).

The endothelium is the inner lining of the blood vessels.

 

Inflammation affects brain volume.

Lower performance on recognition memory and smaller left medial temporal lobe volumes (a part of the brain) was found in participants with detectable levels of the inflammatory marker CRP, when compared with those with undetectable CRP levels (Bettcher BM, et.al. 2012).

 

 

Mild cognitive impairment has been associated with increased levels of several inflammatory markers (Trollor JN, et.al., 2010).

The inflammatory marker hs-CRP which is a more sensitive marker of inflammation than the regular CRP is especially important both as a cardiovascular risk factor and also an important factor related to brain function.

Even at the age of 63, it was found that women in this study with higher hs-CRP levels had worse performance in executive function (Wersching H, et.al., 2010). Changes in the brain were also observed.

High hs-CRP has been found to predict poorer memory 12 years later in women between 60 and 70 years of age (Komulainen P, et.al., 2007).

 

The earlier you adopt a lifestyle and eating habits that will reduce low-grade inflammation, the better off you will be.

 

REFERENCE:

 

1. Heringa, S. M., Van den Berg, E., Reijmer, Y. D., Nijpels, G., Stehouwer, C. D. A., Schalkwijk, C. G., … & Dekker, J. M. (2014). Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population–the Hoorn StudyPsychoneuroendocrinology40, 108-118.

2.  Bettcher, B. M., Wilheim, R., Rigby, T., Green, R., Miller, J. W., Racine, C. A., … & Kramer, J. H. (2012). C-reactive protein is related to memory and medial temporal brain volume in older adultsBrain, behavior, and immunity26(1), 103-108.

3. Trollor, J. N., Smith, E., Baune, B. T., Kochan, N. A., Campbell, L., Samaras, K., … & Sachdev, P. (2010). Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging Study. Dementia and geriatric cognitive disorders30(6), 569-578.

4. Wersching, H., Duning, T., Lohmann, H., Mohammadi, S., Stehling, C., Fobker, M., … & Deppe, M. (2010). Serum C-reactive protein is linked to cerebral microstructural integrity and cognitive functionNeurology74(13), 1022-1029.

5. Komulainen, P., Lakka, T. A., Kivipelto, M., Hassinen, M., Penttilä, I. M., Helkala, E. L., … & Rauramaa, R. (2007). Serum high sensitivity C-reactive protein and cognitive function in elderly women. Age and Ageing36(4), 443-448.

 


Learn To Eat Program:

Recommendations that work. Foods that can reduce low-grade inflammation. This is not a regular diet.

 

How To Improve Your Memory By Drinking These 2 Things

Posted by on Brain, General Health, Green tea, Memory | 0 comments

Coffee and tea are 2 very common beverages that people drink daily. Most people, however, drink either coffee or tea, but rarely both.

Interesting research shows that you may get more benefits if you drink both coffee and tea on a regular basis.

Coffee and tea, and especially green tea provide antioxidants.

The most common ones are polyphenols in coffee and catechins in tea.

Coffee and tea also contain caffeine, but tea also contains L-theanine which is an amino acid.

Theanine provides additional benefits.

When 50 mg of caffeine was studied with or without 100 mg of L-theanine, it showed that caffeine improved subjective alertness and accuracy (Owen GN, et.al., 2008). The caffeine and L-theanine combination improved both speed and accuracy of performance.

People drinking 3-5 cups of coffee daily at midlife provided good observations to have a decreased risk of dementia and Alzheimer’s disease by about 65% at late-life (Eskelinen MH, Kivipelto M., 2010).

 

Caffeine is beneficial.

Research has also shown that the moderate amount of caffeine found in coffee protected against both cardiovascular disease and Alzheimer’s disease (You DC, et.al., 2011).

Both coffee and tea have a protective effect on the nervous system. They also have been associated with a lower risk of Parkinson’s disease (Hu G, et.al., 2007).

How To Improve Memory By Drinking Tea and Coffee

How to improve your memory can be as simple as drinking coffee and tea daily. If you are already doing that, you may even want to increase the amount you are drinking, unless you are very sensitive to caffeine.

You should not drink either coffee or tea too late in the day, since the caffeine may affect your sleep. Moreover, you will spend more than 6 hours to eliminate caffeine from your body.


References:

Eskelinen, M. H., & Kivipelto, M. (2010). Caffeine as a protective factor in dementia and Alzheimer’s disease. Journal of Alzheimer’s Disease, 20(s1), S167-S174.

You, D. C., Kim, Y. S., Ha, A. W., Lee, Y. N., Kim, S. M., Kim, C. H., … & Lee, J. M. (2011). Possible health effects of caffeinated coffee consumption on Alzheimer’s disease and cardiovascular disease. Toxicological research, 27(1), 7.

Hu, G., Bidel, S., Jousilahti, P., Antikainen, R., & Tuomilehto, J. (2007). Coffee and tea consumption and the risk of Parkinson’s disease. Movement Disorders, 22(15), 2242-2248.

Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutritional neuroscience, 11(4), 193-198.


If you like to drink green tea, you should drink it rather than taking it in capsule form. But, if you don’t like drinking tea, capsules are a good alternative.

 

Read this for more information…

3 Reasons Why Improving Insulin Sensitivity Will Improve Your Memory

Posted by on Brain, Insulin resistance, Memory | 0 comments

An association between hyperglycemia (which is high blood glucose levels) and cognitive dysfunction have been found in relatively healthy older individuals (Umegaki H, et.al, 2017). Insulin resistance which happens when the insulin sensitivity in your tissue decreases was found to be associated with memory impairment and the individuals with diabetes were worse.

The research makes it clear that if you want to improve your memory or prevent it from getting worse, you need to implement strategies to improve insulin sensitivity.

Even in young adults, hyperglycemia is associated with subtle brain injury and impaired memory and attention (Weinstein G, et.al., 2015).

When you eat a meal consisting of high glycemic index carbohydrates, your blood glucose levels will increase too much.

While you may tolerate that occasionally, eating that way every day will affect your insulin sensitivity, and it will not be good for your memory.

It has been proposed that toxins generated by insulin resistance transit across the blood-brain barrier into the brain, where they induce insulin resistance to the brain tissue, creating inflammation and cell death (De La Monte SM, 20120.)

Diets high in trans-fat and saturated fat adversely affect cognition. Fruit, vegetables, cereal, and fish are associated with lower risk of dementia and better cognition (Parrot MD, Greenwood CE, 2007). As you get more insulin resistant, ingestion of rapidly absorbed, high-glycemic index carbohydrates increase oxidative stress and inflammatory compounds.

Cereals were listed as associated with lower risk. But, you have to be careful with cereals because most cereals are not low glycemic index. For that reason, cereals may adversely affect your insulin sensitivity and not be your best choice. That does not mean you should avoid all carbohydrates. There are some healthy, very low glycemic index carbohydrates like beans, lentils, and vegetables.                                                                                                           

Also keep in mind that fish is contaminated now, especially with mercury. Contaminants have shown to interfere with the benefits of fish. It is better to use a high-quality fish oil to increase your omega 3 fatty acid intake. If you eat fish, wild salmon is still your best choice.

This is a summary of the 3 reasons why improving insulin sensitivity will improve your memory.                

Increasing insulin sensitivity and eating low glycemic index food, what you eat will not increase your blood glucose that high. It will also not increase oxidative stress and inflammatory compounds. You will end up with less cell death and brain damage and instead see the improved memory.


References:

Umegaki, H., Makino, T., Uemura, K., Shimada, H., Hayashi, T., Cheng, X. W., & Kuzuya, M. (2017). The associations among insulin resistance, hyperglycemia, physical performance, diabetes mellitus, and cognitive function in relatively healthy older adults with subtle cognitive dysfunctionFrontiers in aging neuroscience9.

Weinstein, G., Maillard, P., Himali, J. J., Beiser, A. S., Au, R., Wolf, P. A., … & DeCarli, C. (2015). Glucose indices are associated with cognitive and structural brain measures in young adults. Neurology84(23), 2329-2337.

Suzanne, M. (2012). Metabolic derangements mediate cognitive impairment and Alzheimer’s disease: role of peripheral insulin resistance diseases. Panminerva medica54(3), 171.

Parrott, M. D., & Greenwood, C. E. (2007). Dietary influences on cognitive function with aging. Annals of the New York Academy of Sciences1114(1), 389-397.

Greenwood, C. E., & Winocur, G. (2005). High-fat diets, insulin resistance and declining cognitive function. Neurobiology of aging26(1), 42-45.


Learn To Eat Program:

Recommendations that work. Improve your memory with the food you eat. This is not a regular diet program