How do changes in body composition affect cardiovascular risk?

This study included 1048 participants between the age of 50 and 80 years old without cardiovascular disease (Hu T, et. al., 2023).

The researchers investigated the associations of 2-year changes in fat percentage and fat-free mass percentage with occurring cardiovascular events.

This is what they found. The participants with a fat% gain of 2% or more had an increased risk of cardiovascular events when compared with participants with a stable fat%.

They also found that fat-free mass percentage loss of 2% was associated with an increased risk of cardiovascular events.

Reference

Tingting Hu, Yun Shen, Weijie Cao, Yiting Xu, Yufei Wang, Xiaojing Ma, Yuqian Bao. Two-year changes in body composition and future cardiovascular events: a longitudinal community-based study. Nutr Metab (Lond). 2023 Jan 31;20(1):4.

 

This formula was designed to support healthy glucose, cholesterol metabolism. 

Berberine also suppresses neuroinflammatory responses through activation of the AMP-activated protein kinase (Lu DY, et al., 2010).

Berberine significantly down-regulates cyclo-oxygenase-2 (COX-2) expression in microglia cells. COX-2 are inflammatory promoting enzymes. Microglia cells are located throughout the brain and spinal cord.