Why you don’t want to eat food that results in high blood glucose levels?
We know that diabetes can lead to serious complications because of elevated blood glucose
We don’t, however, have to be diagnosed with diabetes to be exposed to the negative effects of
elevated blood glucose.
What is called protein glycation and formation of advanced glycation end products play an
an important role in diabetic complications like retinopathy, nephropathy, neuropathy and
cardiomyopathy and also other diseases like rheumatoid arthritis, osteoporosis, and aging
(Singh VP, et.al., 2014).
Glycation of proteins takes place when glucose reacts with proteins because it is
Advanced glycation end products, is formed when we have high blood glucose levels and is
causing inflammation and endothelial damage (de Vries MA, et.al., 2014).
The endothelium is the inner layer of the blood vessel wall.
Eating food with a high glycemic index leads to the quick and high elevation of your blood glucose.
This results in acute inflammation causing endothelial dysfunction which may be one of the
earliest events forming atherosclerosis.
Processed food, bread, cookies, candy, and ice cream are some examples of high glycemic
A plant-based diet tends to have a lower glycemic index if you are careful with potatoes,
processed grains, and very sweet fruit. Beans and lentils are examples of lower glycemic index
carbohydrates which will also lower the glycemic index of a meal since they slow down the
absorption of the glucose from grains.
de Vries MA, Klop B, Janssen HW, Njo TL, Westerman EM, Castro Cabezas M. Postprandial
inflammation: targeting glucose and lipids. Adv Exp Med Biol. 2014;824:161-70.
Singh VP, Bali A, Singh N, Jaggi AS. Advanced glycation end products and diabetic
complications. Korean J Physiol Pharmacol. 2014 Feb;18(1):1-14.