Blood Glucose Support
This formula contains Fenugreek and two other herbs traditionally known to help support normal blood sugar levels.
A review of ten studies found that Fenugreek significantly lowered fasting blood glucose and HbA1c, a measurement of long-term glucose control (Neelakantan N, et al. 2014).
Bitter Melon has shown a reduction in HbA1c and cardiovascular risk factors (Rahman IU, et al. 2015). Research indicates that Gymnema Sylvestre helps reduce fasting blood glucose and blood glucose levels after a meal (Al-Romaiyan A, et al. 2010, Pothuraju R, et al. 2014). Chronically higher blood glucose levels have a negative influence on cognition.
High blood glucose was found to be related to poorer overall performance and greater rates of decline in general cognitive ability (Seetharaman S, et.al., 2015).
In this study higher blood glucose levels in the normal range were associated with lower gray/white matter regional volumes in the brain (Mortby ME, et.al., 2012).
This research shows that blood glucose levels don’t have to be extremely high before it starts to affect our brain function.
Ideally, it’s better to keep blood glucose levels in the low normal range and avoiding high spikes after a meal.
Increasing evidence suggests that the after-meal effect of lipoproteins and glucose may be involved in the inflammatory process preceding the development of atherosclerosis (de Vries MA, et.al., 2014).
Advanced glycation end products, formed during hyperglycemia, cause inflammation and endothelial damage. The endothelium is the inner layer of the blood vessel wall.
Al-Romaiyan A1, Liu B, Asare-Anane H, Maity CR, Chatterjee SK, Koley N, Biswas T, Chatterji AK, Huang GC, Amiel SA, Persaud SJ, Jones PM. A novel Gymnema sylvestre extract stimulates insulin secretion from human islets in vivo and in vitro. Phytother Res. 2010 Sep;24(9):1370-6. doi: 10.1002/ptr.3125.
de Vries MA, Klop B, Janssen HW, Njo TL, Westerman EM, Castro Cabezas M. Postprandial inflammation: targeting glucose and lipids. Adv Exp Med Biol. 2014;824:161-70.
Mortby ME, Janke AL, Anstey KJ, Sachdev PS, Cherbuin N. High “normal” blood glucose is associated with decreased brain volume and cognitive performance in the 60s: the PATH through life study. PLoS One. 2013 Sep 4;8(9):e73697.
Neelakantan N1, Narayanan M, de Souza RJ, van Dam RM. Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Nutr J. 2014 Jan 18;13:7. doi: 10.1186/1475-2891-13-7.
Pothuraju R1, Sharma RK, Chagalamarri J, Jangra S, Kumar Kavadi P. A systematic review of Gymnema sylvestre in obesity and diabetes management. J Sci Food Agric. 2014 Mar 30;94(5):834-40. doi: 10.1002/jsfa.6458. Epub 2013 Nov 19.
Rahman IU, Khan RU, Rahman KU, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J. 2015 Jan 26;14(1):13. [Epub ahead of print]
Seetharaman S, Andel R, McEvoy C, Dahl Aslan AK, Finkel D, Pedersen NL. Blood glucose, diet-based glycemic load and cognitive aging among dementia-free older adults. J Gerontol A Biol Sci Med Sci. 2015 Apr;70(4):471-9.