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Can your bacterial flora clog up your arteries?

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Can your bacterial flora clog up your arteries?

Can your bacterial flora clog up your arteries?

Posted by on Eating, General Health, Health, Inflammation | 0 comments

 

As more and more research is being conducted on the bacterial flora of the intestines, the more we realize how important it is to have an abundant and diverse bacterial population of the healthy kind. The researchers of the following study found that patients with symptomatic atherosclerosis had more of certain gut bacteria than healthy controls (Karlsson FH, et.al., 2012).

The bacterial flora is associated with our inflammatory status, that’s what these researchers suggested, and we know that inflammation in the gastrointestinal tract creates inflammation other places in the body and is a risk factor for atherosclerosis.

Your bacterial flora can for that reason clog up your arteries if you have the wrong type of bacteria.

When bacteria in atherosclerotic plaques were examined, specific types were identified, and some types correlated with total cholesterol and fibrinogen levels (Ziganshina EE, et.al., 2016). Periodontal disease has also been associated with atherosclerosis.

Bacterial DNA was detected in atherosclerotic plaque, and the amount of DNA correlated with the number of leukocytes (a type of white blood cell), found in the atherosclerotic plaque (Koren O, et.al., 2011). Leukocytes are involved in the inflammatory response.

Several types of bacteria in the mouth and the gut correlated with blood cholesterol levels. How can you increase the number of friendly bacteria in the gastrointestinal tract?

These bacteria feed on a variety of plant fiber. When you eat a plant-based diet with a variety of vegetables, legumes, nuts and seeds, your healthy flora will increase, and these bacteria reduce inflammation.

References

Karlsson FH, Fåk F, Nookaew I, Tremaroli V, Fagerberg B, Petranovic D, Bäckhed F, Nielsen J. Symptomatic atherosclerosis is associated with an altered gut metagenome. Nat Commun. 2012;3:1245.

Koren O, Spor A, Felin J, Fåk F, Stombaugh J, Tremaroli V, Behre CJ, Knight R, Fagerberg B, Ley RE, Bäckhed F. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4592-8.

Ziganshina EE, Sharifullina DM, Lozhkin AP, Khayrullin RN, Ignatyev IM, Ziganshin AM. Bacterial Communities Associated with Atherosclerotic Plaques from Russian Individuals with Atherosclerosis. PLoS One. 2016 Oct 13;11(10):e0164836.

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Green Tea Provides many Benefits, but you Need to Know this Before you Drink it.

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Green Tea Provides many Benefits, but you Need to Know this Before you Drink it.

Green Tea Provides many Benefits, but you Need to Know this Before you Drink it.

Posted by on Bloodsugar, Cholesterol, General Health | 0 comments

The antioxidants called catechins in green tea is the main reason for the many benefits green tea provides.

It is very important to be insulin sensitive and have good glucose control because elevated blood glucose levels and insulin resistance cause inflammation and damage tissue.

When 17 studies were reviewed which included 1133 participants, the researchers found that green tea consumption significantly reduced fasting blood glucose and hemoglobin A1c (Hb A1c) (Liu K, et.al., 2013). Subgroup analysis also found that green tea significantly reduced fasting insulin.

 

As you get more insulin sensitive, you don’t need as much insulin to transfer the blood glucose into the cells. As blood levels of insulin go down, you will also start to use more fat for energy.
The following study investigated green tea extract in capsule form instead of drinking green tea. (Bogdanski P, et.al., 2012).The participants were obese, had high blood pressure and took either a capsule of 379 mg of green tea extract or a placebo capsule for 3 months. This was the results.

 

 

 

Total cholesterol, LDL (low-density lipoprotein) and triglycerides decreased, while HDL (high-density lipoprotein) increased in the treatment group, but not in the placebo group. The group taking the green tea extract also had a significant decrease in diastolic and systolic blood pressure as well as a significant decrease in TNF-alpha and CRP, both inflammatory markers. Glucose, insulin and insulin resistance also improved.

 

This is all very good, but you need to be careful when you buy green tea.

 

 

When black, green, white and oolong tea sold in tea bags were steeped for 3-4 minutes and the tea tested, this is what was found (Schwalfenberg G, et.al., 2013).

73% of teas brewed for 3 minutes and 83% brewed for 15 minutes had lead levels considered unsafe for consumption during pregnancy and lactation. Aluminum levels were above recommended guidelines in 20% of the brewed teas. 

 

No mercury was found at detectable levels in any of the brewed samples.

Tea can possibly also be contaminated with pesticides.

You need to be sure that the tea you buy is of high quality and not grown in contaminated soil. This is something to keep in mind when you buy green tea extract also.

 

 

References

Bogdanski P, Suliburska J, Szulinska M, Stepien M, Pupek-Musialik D, Jablecka A. Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutr Res. 2012 Jun;32(6):421-7. doi: 10.1016/j.nutres.2012.05.007.

Liu K, Zhou R, Wang B, Chen K, Shi LY, Zhu JD, Mi MT. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials. Am J Clin Nutr. 2013 Aug;98(2):340-8.

Schwalfenberg G, Genuis SJ, Rodushkin I.The benefits and risks of consuming brewed tea: beware of toxic element contamination. J Toxicol. 2013;2013:370460.

 

 

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Magnesium is Even More Important than We Used to Think

Posted by on Brain, Cardiovascular Disease, Eating, Gastrointestinal Health, General Health, General Health, Health, magnesium, Vitamin D | 0 comments

Magnesium is Even More Important than We Used to Think

Posted by on Brain, Cardiovascular Disease, Eating, Gastrointestinal Health, General Health, General Health, Health, magnesium, Vitamin D | 0 comments

Research is documenting how functions, organs, and nutrients are all interconnected. We cannot look at anything as separate entities anymore if we are going to get an accurate impression of what happens physiologically from the input of nutrient intake as well as exercise. The GI tract is one example where researchers have documented communication between the GI tract and the brain. We know the brain also communicates with the GI tract.

Intestinal absorption and subsequent metabolism of a nutrient, to a certain extent, is dependent on the availability of other nutrients.

The following research is showing us how the intake and the impact of magnesium are affecting vitamin D levels.

Image result for magnesium

Magnesium assists in the activation of vitamin D because all of the enzymes that metabolize vitamin D seem to require magnesium (Uwitonze AM, Razzaque MS, 2018).

Deficiency in either of these nutrients is reported to be associated with skeletal deformities, cardiovascular diseases, and the metabolic syndrome.

The next study indicates the same thing. The researchers found that higher intake of magnesium resulted in higher blood levels of 25 hydroxyvitamin D (25(OH)D), which is the most reliable way to measure vitamin D status (Deng X, et.al., 2013).

They also found associations of serum 25(OH)D with mortality, particularly due to cardiovascular disease and colorectal cancer, and they were modified by magnesium intake. Magnesium has shown to reduce calcification of the arteries (Hruby A, et.al., 2014).

This means that if you must take a very high amount of vitamin D to keep your vitamin D level in a good range, you most likely need magnesium. If you take enough magnesium in a well-absorbed form, you should not need to take high amounts of vitamin D to keep it at a good level. What we also learn from research like this, is how important it is to take magnesium or any of the other common minerals in a formula that combines these minerals, since they affect each other. Amino acid chelates are the best form to take minerals because they are better absorbed and better tolerated. They don’t cause gastrointestinal irritation.

 

 

References
Deng X, Song Y, Manson JE, Signorello LB, Zhang SM, Shrubsole MJ, Ness RM, Seidner DL, Dai Q. Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med. 2013 Aug 27;11:187.

Hruby A1, O’Donnell CJ2, Jacques PF1, Meigs JB3, Hoffmann U4, McKeown NM5. Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study. JACC Cardiovasc Imaging. 2014 Jan;7(1):59-69.

Uwitonze AM, Razzaque MS. Role of Magnesium in Vitamin D Activation and Function. J Am Osteopath Assoc. 2018 Mar 1;118(3):181-189.

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This has Shown to Improve Memory, and it is Easy to Implement

Posted by on Alzheimer’s, Arthritis, Brain, Cancer, Cardiovascular Disease, Diabetes, General Health, Health, Inflammation, Memory | 0 comments

This has Shown to Improve Memory, and it is Easy to Implement

Posted by on Alzheimer’s, Arthritis, Brain, Cancer, Cardiovascular Disease, Diabetes, General Health, Health, Inflammation, Memory | 0 comments

Image result for low grade inflammationLow grade inflammation, the type of inflammation you usually don’t know you have, is harmful for all tissue, including the brain. Curcumin found in the spice turmeric has been shown to decrease inflammation and was for that reason studied to determine if it could provide protection for the brain.

40 participants were given either curcumin in a bioavailable form twice daily or a placebo for 18 months (Small GW, et.al., 2018). The participants did not have dementia, and the researchers found that taking curcumin twice daily, improved their memory and attention.

PET scanning suggested that the improvements were associated with a decrease in amyloid and tau accumulation in brain areas regulating mood and memory. Image result for amyloid and tau alzheimers brain

Amyloid and tau accumulation are usually found in the brains of patients with Alzheimer’s disease.

Earlier research with another bioavailable form of curcumin showed that 1 hour after taking the curcumin, the participants experienced significant improvement in attention and working memory (Cox KH, et.al., 2015).

Taking a capsule twice a day is very easy and something everybody can do.

References
Small GW1, Siddarth P2, Li Z2, Miller KJ2, Ercoli L2, Emerson ND2, Martinez J2, Wong KP2, Liu J2, Merrill DA2, Chen ST2, Henning SM2, Satyamurthy N2, Huang SC2, Heber D2, Barrio JR2. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial. Am J Geriatr Psychiatry. 2018 Mar;26(3):266 277.

Cox KH1, Pipingas A1, Scholey AB2. Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. 2015 May;29(5):642-51.

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Curcumin is a good antioxidant, but it is especially effective in helping to reduce inflammation. For these reasons, curcumin provides many health benefits.

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Your Blood Glucose Level after You Eat can Affect Your Risk for Cardiovascular Disease.

Posted by on Bloodsugar, Cardiovascular Disease, Diabetes, Eating, General Health, Glucose, Health, Heart disease | 0 comments

Your Blood Glucose Level after You Eat can Affect Your Risk for Cardiovascular Disease.

Posted by on Bloodsugar, Cardiovascular Disease, Diabetes, Eating, General Health, Glucose, Health, Heart disease | 0 comments

Your blood glucose level after you eat can affect your risk for cardiovascular disease. Several studies show a correlation between blood glucose levels and what happens to your arteries. The most common ways to evaluate the blood glucose metabolism is to measure fasting blood glucose and Hemoglobin A1c (HbA1c). Hemoglobin A1c is usually used to monitor long-term glucose control, 2-3 months.

Image result for blood glucoseMore and more research is, however, documenting the importance of also knowing what the blood glucose level is after a meal, and that is not checked routinely.

In the following study, the participants were divided into 4 groups based on coronary angiography (Sasso FC, et.al., 2004). One group had no significant stenosis (calcification), the other groups had documented disease in 1 and up to 3 vessels. Several tests were performed to evaluate the glucose metabolism, including the glucose and insulin levels after eating.

For patients with a so-called normal glucose tolerance, it was interesting that the most important test correlating with cardiovascular risk was the glucose level after eating, and the next was Hemoglobin A1c.

In patients with coronary artery disease the researchers showed that even with normal Hemoglobin A1c levels, the participants with an abnormal glucose tolerance test (glucose after a meal) had greater progression of coronary artery lesions (Wang H, et.al., 2014).

It was not even a difference in risk between patients with an impaired glucose tolerance and patients who had type 2 diabetes. This shows that you don’t have to have progressed to having diabetes to have an increased risk for cardiovascular disease. Researchers have found that there is a linear relationship between the risk of cardiovascular death and the 2-hour glucose tolerance test (Leiter LA, et.al., 2005).

Image result for cardiovascular disease and glucose level

The 2 -hour glucose tolerance test measures the blood glucose level 2 hours after a test drink has been ingested.

These researchers found increased mortality at an oral 2-hour glucose tolerance test of approximately 90 mg/dl which is well below the level of what type 2 diabetes patients have.

Research is showing us that what we used to think of as normal and good test results are not good enough. That’s probably why we see a lot of people dying from a cardiovascular disease with laboratory values in the normal range.

References
Leiter LA, Ceriello A, Davidson JA, Hanefeld M, Monnier L, Owens DR, Tajima N, Tuomilehto J ; International Prandial Glucose Regulation Study Group. Clin Ther. 2005;27 Suppl B:S42-56.

Sasso FC, Carbonara O, Nasti R, Campana B, Marfella R, Torella M, Nappi G, Torella R, Cozzolino D, Glucose metabolism and coronary heart disease in patients with normal glucose tolerance. JAMA. 2004 Apr 21;291(15):1857-63.

Wang H, Tang Z, Li X, Hu B, Feng B. Angiographic evaluation of the effects of glucose metabolic status on progression of coronary artery lesions in patients with coronary artery disease. J Diabetes. 2014 Nov;6(6):541-6.

 

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Decrease Inflammation after a Meal by Including These 2 Ingredients

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Decrease Inflammation after a Meal by Including These 2 Ingredients

Posted by on Eating, General Health, Health, Inflammation | 0 comments

Inflammation and oxidative stress are usually connected, and both can affect your blood vessels in a negative way. Both are known to cause damage to the endothelium, the inner lining of the blood vessels.

Depending on what kind of food the meal includes, both inflammation and oxidative stress can increase. To evaluate if adding processed tomato products would make a difference, the participants of this study consumed high fat meals known to induce oxidative stress on 2 separate occasions (Burton-Freeman B, et.al., 2012).

Image result for beans and tomato pictureOne time a processed tomato product was added, and the other time a non-tomato product was used.

Several tests were performed before and after, and it was found that the tomato product significantly
reduced the high fat meal induced LDL oxidation and the rise in IL-6, an inflammatory marker. 

Beans is another food that has shown to modify cardiovascular risk.

Image result for black bean pasta tomato

When meals containing either black beans, fiber matched meals or antioxidant capacity matched meals were compared this was the result (Reverri EJ, et.al., 2015).

Insulin was lower after the black bean meal and a trend for decreasing oxidized LDL was found for both the the beans and the antioxidant matched meal.

Oxidized LDL is the most harmful form of LDL cholesterol.

If you like pasta, you can make the meal healthier by adding beans to a sauce which includes
processed tomatoes.

By taking a well absorbed form of curcumine you can further decrease inflammation (Sahebkar A, 2014).

 

References

Burton-Freeman B, Talbot J, Park E, Krishnankutty S, Edirisinghe I. Protective activity of processed tomato products on postprandial oxidation and inflammation: a clinical trial in healthy weight men and women. Mol Nutr Food Res. 2012 Apr;56(4):622-31.

Reverri EJ, Randolph JM, Steinberg FM, Kappagoda CT, Edirisinghe I, Burton-Freeman BM. Black Beans, Fiber, and Antioxidant Capacity Pilot Study: Examination of Whole Foods vs. Functional Components on Postprandial Metabolic, Oxidative Stress, and Inflammation in Adults with Metabolic Syndrome. Nutrients. 2015 Jul 27;7(8):6139-54.

Sahebkar A1. Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? Evidence from a meta-analysis. Phytother Res. 2014 May;28(5):633-42.

Image result for reduce inflammation photo

 

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Curcumin is a good antioxidant, but it is especially effective in helping to reduce inflammation. For these reasons, curcumin provides many health benefits.

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This was found to be the most important risk factor for atherosclerosis.

Posted by on Cardiovascular Disease, Eating, Eating, General Health, Health | 0 comments

This was found to be the most important risk factor for atherosclerosis.

This was found to be the most important risk factor for atherosclerosis.

Posted by on Cardiovascular Disease, Eating, Eating, General Health, Health | 0 comments

If you want to function well and stay healthy, you need a vascular system that can provide good blood supply to all tissue in your body, especially your brain and heart.

The reason is that the blood provides nutrients and oxygen to the whole body. Without that, all tissue will degenerate.

You can imagine what that would mean to your brain and heart.

As we get older the more likely it is that the blood vessels will start to collect deposits and get narrower, that’s called atherosclerosis.

There are several blood tests used to determine the risk for cardiovascular disease.

 

What you really want to know is the health of your arteries.

The following research is very interesting. It included 4184 participants without what’s considered to be conventional cardiovascular risk factors (Fernandez-Friera L, et.al., 2017). The status of their vascular system was evaluated by ultrasound detected carotid, iliofemoral and abdominal aortic plaques and coronary artery calcification. The researchers also included a lot of different blood tests as well as lifestyle evaluation.

 

Plaque or coronary artery calcification was present in 49.7% of the participants.

The real value of this study is the identification of the most relevant risk factor which was found to be LDL cholesterol.

The results indicate that atherosclerosis in both men and women develops above an LDL cholesterol threshold of approximately 50 to 60 mg/dl. This is much lower than what was thought necessary for a healthy cardiovascular system.

This means that if you want to have arteries free of deposits, you need to implement a diet and lifestyle that has shown to do that.

This is not impossible and does not have to be that difficult.

 

What you eat is the most important factor.

When people eating a high protein, low carbohydrate diet for one year were compared with a group eating a plant-based diet also for a year, this was the results.

All the participants were evaluated at the beginning and at the end of the study using myocardial
perfusion imaging, echocardiography and several blood tests (Fleming RM, 2000).

The group eating the plant-based diet improved their cardiovascular function and had less plaque in their arteries a year later when measured.

The group eating a high protein, low carbohydrate diet had more plaque than when they started a year ago, and risk factors for cardiovascular disease like fibrinogen a clotting factor, Lp(a) and CRP an inflammatory marker were all worse.

 

References

Fernández-Friera L1, Fuster V2, López-Melgar B3, Oliva B4, García-Ruiz JM5, Mendiguren J6, Bueno H7, Pocock S8, Ibáñez B9, Fernández-Ortiz A10, Sanz J11. Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors. J Am Coll Cardiol. 2017 Dec 19;70(24):2979- 2991. doi: 10.1016/j.jacc.2017.10.024.

Fleming RM1. The effect of high-protein diets on coronary blood flow. Angiology. 2000 Oct;51(10):817-26.

 

 

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If you don’t get enough of this mineral it could increase your risk for cardiovascular disease.

Posted by on Cardiovascular Disease, General Health, Health | 0 comments

If you don’t get enough of this mineral it could increase your risk for cardiovascular disease.

If you don’t get enough of this mineral it could increase your risk for cardiovascular disease.

Posted by on Cardiovascular Disease, General Health, Health | 0 comments

A lot of people may think that they need to completely change their life style to reduce their risk for cardiovascular disease, and they don’t want to do that.

If you have an unhealthy lifestyle, I would absolutely recommend that you make changes, but sometimes you can actually reduce your risk for serious disease very easily.

The researchers in the following study show us an easy way to reduce the risk of death from coronary heart disease (Kieboom BC, et.al., 2016).

 

9820 participants, both men and women, were followed for an average of 8.7 years. The results showed that low serum magnesium was associated with an increased risk of coronary heart disease and sudden cardiac death. It also accelerated atherosclerosis (increased thickness of the inner lining of the carotid artery wall) and affected the heart rate.

Getting deposits in the arteries are not good, but this did not explain the increased risk of dying, so there is even more to the beneficial effects of magnesium than this research can explain.

Magnesium’s ability to stop already established vascular calcification has been documented in a laboratory study and was associated with magnesium transport through the cell membrane (Montes de Oca A, et.al., 2014).

There are several studies showing that magnesium can reduce artery calcification. This one showed decreased arterial calcification as the magnesium intake increased when measured with Computed Tomography (Hruby A, et.al., 2014).

Magnesium is best absorbed in the form of an amino acid chelate and is not causing gastrointestinal irritation like magnesium oxide is known to do

 

References

 

Hruby A, O’Donnell CJ, Jacques PF, Meigs JB, Hoffmann U, McKeown NM, Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study. JACC Cardiovasc Imaging. 2014 Jan;7(1):59-69.

Kieboom BC, Niemeijer MN, Leening MJ, van den Berg ME, Franco OH, Deckers JW, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death. J Am Heart Assoc. 2016 Jan 22;5(1).

Montes de Oca A, Guerrero F, Martinez-Moreno JM, Madueño JA, Herencia C, Peralta A, Almaden Y, Lopez I, Aguilera-Tejero E, Gundlach K, Büchel J, Peter ME, Passlick-Deetjen J, Rodriguez M, Muñoz-Castañeda JR. Magnesium inhibits Wnt/β-catenin activity and reverses the osteogenic transformation of vascular smooth muscle cells. PLoS One. 2014 Feb 25;9(2):e89525.

 

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Is a low carbohydrate, high protein, high fat diet the best way to eat?

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Is a low carbohydrate, high protein, high fat diet the best way to eat?

Is a low carbohydrate, high protein, high fat diet the best way to eat?

Posted by on General Health | 0 comments

A low carbohydrate, high protein and high fat diet has been promoted by many as the solution to a variety of conditions.

 

What is the research telling us?

When data from 272,216 people were examined, low carbohydrate diets were associated with a significantly higher risk for all-cause mortality (Noto H, et.al., 2013).

Another study followed 85168 women and 44548 men for 26 and 20 years (Fung TT, et al. 2010).

At the follow up, a low carbohydrate diet with emphasis either on animal sources of fat and protein, or a low carbohydrate diet with an emphasis on vegetable sources of fat and protein were compared.

 

The researchers found that the animal sourced, low carbohydrate, high fat and high protein diet was associated with higher all-cause mortality, higher cardiovascular mortality and higher cancer mortality when compared with the diet emphasizing low carbohydrates with fat and protein from vegetable sources.

 

 

What happened when survivors from myocardial infarctions followed a low carbohydrate diet with higher intake of animal sources of fat and protein?

 

The researchers found that it was associated with higher all-cause mortality (Li S, et.al., 2014).

 

Apparently eating a high fat and high protein diet is not healthy, especially if the sources of fat and protein are from animal sources.

 

 

References

Fung TT, van Dam RM, Hankinson SE, Stampfer M, Willett WC, Hu FB. Low-carbohydrate diets and all-cause and cause-specific mortality: two cohort studies. Ann Intern Med. 2010 Sep 7;153(5):289-98.

 

Li S, Flint A, Pai JK, Forman JP, Hu FB, Willett WC, Rexrode KM, Mukamal KJ, Rimm EB. Low carbohydrate diet from plant or animal sources and mortality among myocardial infarction survivors. J Am Heart Assoc. 2014 Sep 22;3(5).

 

Noto H, Goto A, Tsujimoto T, Noda M.  Low-carbohydrate diets and all-cause mortality: a systematic review and meta-analysis of observational studies. PLoS One. 2013;8(1):e55030.

 

 

 

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Help improve brain function and decrease inflammation with small amounts of this mineral.

Posted by on Brain, General Health, Health, Inflammation | 0 comments

Help improve brain function and decrease inflammation with small amounts of this mineral.

Help improve brain function and decrease inflammation with small amounts of this mineral.

Posted by on Brain, General Health, Health, Inflammation | 0 comments

The research on the mineral boron started many years ago, and the more it has been studied the more we realize how important this mineral is. It turns out that it is involved in a huge number of important functions (Pizzorno L, 2015).

The following article describes how low boron intake can affect brain function and cognitive performance (Penland JG, 1994).

 

When compared to high intake of boron, low boron intake resulted in significant poorer performance in several areas, some of were eye-hand coordination, attention, long and short-term memory.

 

In a double-blind, placebo-controlled study conducted on patients diagnosed

with osteoarthritis 2 common inflammatory markers, highly sensitive C-reactive protein (hs-CRP) and TNF-alpha decreased significantly after 1 week of boron supplementation (Naghil MR, et.al., 2011).

 

Boron supplementation has even showed benefits for rheumatoid arthritis.

After 60 days of supplementation with boron, a significant decrease in the inflammatory markers erythrocyte sedimentation rate, C-reactive protein (CRP), IL-1alpha, IL-6 and TNF-alpha were found (Hussain SA, et.al., 2016).

 

Symptoms were also improved.

 

References

Hussain SA, Abood SJ, Gorial FI. The adjuvant use of calcium fructoborate and borax with etanercept in patients with rheumatoid arthritis: Pilot study. J Intercult Ethnopharmacol. 2016 Dec 8;6(1):58-64.

Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MS. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. J Trace Elem Med Biol. 2011 Jan;25(1):54-8. Pizzorno L. Nothing Boring About Boron. ntegr Med (Encinitas). 2015 Aug;14(4):35-48.

Scorei R, Mitrut P, Petrisor I, Scorei I. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis. Biol Trace Elem Res. 2011 Dec;144(1-3):253-63.

 

 

 

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