• The probiotic yeast Saccharomyces boulardii has shown to exert an anti-inflammatory effect on intestinal epithelial cells (Sougioultzis S, et al. 2006).

• Saccharomyces has shown to significantly reduce the frequency and duration of acute diarrhea in children (Billoo AG, et al. 2006. Kurugol Z, et al. 2005).

• There is evidence that Saccharomyces reduces the risk of antibiotic-associated diarrhea in children (Kotowska M, et al. 2005).

Serving Size: 1 Capsule

Servings Per Container: 60

Saccharomyces boulardii ………………………….320 mg…………………….** (3 billion live organisms per capsule)

* Daily value not established

Other Ingredients:

Vegetarian capsule (hydroxypropyl methylcellulose, water) and L-leucine.

References:

Billoo AG, Memon MA, Khaskheli SA, Murtaza G, et al. Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhea. World J Gastroenterol. 2006 Jul 28:12(28):4557-60.

Kotowska M, Albrecht P, Szajewska H. Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea in children: a randomized double-blind placebo-controlled trial. Aliment Pharmacol Ther. 2005 Mar 1;21(5):583-90.

Kurugol Z, Koturoglu G. Effects of Saccharomyces boulardii in children with acute diarrhoea. Acta Paediatr. 2005 Jan:94(1):44-7.

Sougioultzis S, Simeonidis S, Bhaskar KR, et al. Saccharomyces boulardii produces a soluble anti-inflammatory factor that inhibits NF-kappaB-mediated IL-8 gene expression. Biochem Biophys Res Commun. 2006 Apr 28;343(1):69-76. Epub 2006 Feb 23.

Gastrointestinal Support