Heart Health and How to Fight Back Against Disease
This substance is very important for the cardiovascular system.
Oxidative stress has been found to be a factor involved in many chronic diseases, and cardiovascular disease is one of them.
This is what was found in the following research when glutathione levels were measured in patients with cardiac disease and compared with a healthy control group.
The researchers wrote that this study provides evidence that cardiac and systemic glutathione deficiency is related to the functional status and structural cardiac abnormalities of patients with cardiac diseases (Damy T, et.al., 2009).
Another study found that glutathione concentrations were lower in all cardiovascular disease cases when compared to the control group (Shimizu H, et.al., 2004).
Both the cerebral infarction cases and cerebral hemorrhage cases had significantly lower total glutathione levels when compared to the control groups.
The researchers wrote that these findings suggest that reduced plasma total glutathione levels are a risk factor for cardiovascular disease, especially for cerebral small vessel disease.
In patients with coronary artery disease, a low level of activity of red-cell glutathione peroxidase 1 was independently associated with an increased risk of cardiovascular events.
The risk of cardiovascular events was inversely associated with increasing quartiles of glutathione peroxidase 1 activity (Blankenberg S, et.al., 2003).
The researchers found that glutathione peroxidase 1 activity was among the strongest univariate predictors of the risk of cardiovascular events.
They also wrote that increasing glutathione peroxidase 1 activity might lower the risk of cardiovascular events.
Blankenberg S, Rupprecht HJ, Bickel C, Torzewski M, Hafner G, Tiret L, Smieja M, Cambien F, Meyer J, Lackner KJ; AtheroGene Investigators.Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease.N Engl J Med. 2003 Oct 23;349(17):1605-13.
Damy T, Kirsch M, Khouzami L, Caramelle P, Le Corvoisier P, Roudot-Thoraval F, Dubois-Randé JL, Hittinger L, Pavoine C, Pecker F .Glutathione deficiency in cardiac patients is related to the functional status and structural cardiac abnormalities. PLoS One. 2009;4(3):e4871.
Shimizu H, Kiyohara Y, Kato I, Kitazono T, Tanizaki Y, Kubo M, Ueno H, Ibayashi S, Fujishima M, Iida M. Relationship between plasma glutathione levels and cardiovascular disease in a defined population: the Hisayama study. Stroke. 2004 Sep;35(9):2072-7.
Glutathione helps your cells reduce free radical damage and also helps lower inflammation.
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