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What’s important for the cardiovascular system is also important for the immune system.

Posted by on 9:00 am BMI, Body fat, Body mass index, Cardiovascular Disease, Cardiovascular disease & waist-hip ratio, Diet, Eating, General Health, Health Risk, Inflammation, Weight, Weight loss | 0 comments

obese man with burgers

 

In this study, participants taking berberine when compared to the placebo group saw a
reduction in triglycerides by 35.9% total cholesterol by 18.1% and LDL (low-density lipoprotein),
the so-called bad cholesterol by 21.1% (Zhang Y, et.al., 2008).

Patients with metabolic syndrome treated with berberine for 3 months showed a decrease in
their BMI (body mass index) from 31.5 to 27.4 in this study (Yang J, et.al., 2012).
Patients diagnosed with the metabolic syndrome usually have several symptoms, they are
insulin resistant, have increased waist circumference and high blood pressure.
The same research also showed that berberine decreased leptin levels from 8.01 to 5.12 μg/L.
Leptin is a hormone that suppresses food intake and induces weight loss. Obese patients are
usually leptin-resistant.

 

 

When 10 studies were reviewed both BMI and waist circumference decreased in participants
taking berberine (Xiong P, et.al.,2020).

It is important to produce a balanced immune response when needed.
An overreaction of the immune system will cause damage and is harmful. It can actually kill us.
Some people are killed by an overreaction of their immune system, not from the invading virus
or bacteria.

This research showed that berberine had an anti-inflammatory effect and initiated a more
balanced immune response (Kalmarzi RN, et.al.,2019).
Inflammation is also a risk factor for cardiovascular disease.

When researchers treated patients with the acute coronary syndrome with berberine, they found
that several inflammatory markers were reduced, C-reactive protein and interleukin-6 were 2 of
them (Meng S, et.al., 2012).

Berberine has shown to be a very useful plant-derived compound benefitting important
functions from blood glucose metabolism, cardiovascular function, fat storage, immune
system and inflammation.

These functions are interconnected, that is why berberine is such a valuable substance.

 

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References:

Kalmarzi RN, Naleini SN, Ashtary-Larky D, Peluso I, Jouybari L, Rafi A, Ghorat F, Heidari N,
Sharifian F, Mardaneh J, Aiello P4, Helbi S, Kooti W.Anti-Inflammatory and Immunomodulatory
Effects of Barberry ( Berberis vulgaris ) and Its Main Compounds.Oxid Med Cell Longev. 2019
Nov 19;2019:6183965.

Meng S, Wang LS, Huang ZQ, Zhou Q, Sun YG, Cao JT, Li YG, Wang CQ. Berberine
ameliorates inflammation in patients with acute coronary syndrome following percutaneous
coronary intervention. Clin Exp Pharmacol Physiol. 2012 May;39(5):406-11.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Berberine improves insulin sensitivity by
inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic
syndrome patients. Evid Based Complement Alternat Med. 2012;2012:363845

Xiong P, Niu L, Talaei S, Kord-Varkaneh H, Clark CCT, Găman MA, Rahmani J, Dorosti M,
Mousavi SM, Zarezadeh M, Taghizade-Bilondi H, Zhang J. The effect of berberine
supplementation on obesity indices: A dose- response meta-analysis and systematic review of
randomized controlled trials. Complement Ther Clin Pract. 2020 May;39:101113.

 

glucose metabolism supportThis formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

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Is a high protein weight loss diet the best approach if you want to lose weight?

Posted by on 9:00 am Body fat, Body mass index, Calories, Diet, Fat, General Health, Get in shape, Lose fat, Stay healthy, Weight, Weight loss, Women, Womens health | 0 comments

Is a high protein weight loss diet the best approach if you want to lose weight?

 

 

pretty girl holding a tray with high protein food

 

In this study, two diets containing different amounts of protein were compared (Smith GI, et al., 2016).

The participants, obese postmenopausal women lost 10% weight using a diet providing either 0.8 g of protein per kg of body weight or a diet providing 1.2 g of protein per kg of body weight.

 

Weight loss usually results in several metabolic benefits, one is improved insulin sensitivity, which means that the transfer of blood glucose into the cells is improved.

 

 

The researchers found that when compared to the low protein diet, the high protein diet prevented the weight loss-induced improvements in muscle insulin signaling and insulin-stimulated glucose uptake.

Not only that but induced adaptations in oxidative stress and cell structural biology pathways, which also are benefits accompanying weight loss, did not take place on the high protein diet.

 

One of the benefits of the high protein diet was that it reduced the weight loss induced a decline in lean tissue mass by 45%.

You don’t want to lose lean muscle mass, but that can be prevented by including exercises, which any good weight loss program will recommend.

 

There are many ways to lose weight, but not all approaches give you the same benefits, so choose wisely.

 

a table with high protein food

 

References:

Smith GI, Yoshino J, Kelly SC, Reeds DN, Okunade A, Patterson BW, Klein S, Mittendorfer B, High-Protein Intake during Weight Loss Therapy Eliminates the Weight-Loss-Induced Improvement in Insulin Action in Obese Postmenopausal Women.Cell Rep. 2016 Oct 11;17(3):849-861.

Can the health of the lining of your intestines affect the size of your waist?

Posted by on 8:27 am Supplements, Waist circumference, Weight | 0 comments

Woman's fingers measuring her belly fatHow big your waist is can tell you something about your risk for cardiovascular disease, the bigger the waist, the more of a risk.

Most people would also prefer to have a slim look.
 

Why do some people have a big waist? Is it just because they eat too much of the wrong food, or could there be another reason as well?

When researchers assessed intestinal permeability in normal to overweight women, they found something interesting(Gummesson A, et al, 2011).
 

Intestinal permeability is an assessment of how big particles the intestinal lining will let through and allow to be absorbed into the blood.  The researchers found that the women with a bigger waist also had increased intestinal permeability. They also found that visceral fat and liver fat were also increased with increased intestinal permeability.
 

If you want to keep a slim waist and stay healthy it is important to keep your gastrointestinal tract healthy.

There are several things you can do to improve your gastrointestinal function. I will write more about that later, but an easy thing you can do is to take a probiotic formula which there are many. Use one which is based on scientific evidence verifying the benefits.

 

 

 

Gastrointestinal support Transparent

Gastrointestinal Support

The probiotic yeast Saccharomyces boulardii has shown to exert an anti-inflammatory effect on intestinal epithelial cells (Sougioultzis S, et al. 2006). Saccharomyces has shown to significantly reduce the frequency and duration of acute diarrhea in children (Billoo AG, et al. 2006. Kurugol Z, et al. 2005). There is evidence that Saccharomyces reduces the risk of antibiotic-associated diarrhoea in children (Kotowska M, et al. 2005).

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Gummesson A1, Carlsson LM, Storlien LH, Bäckhed F, Lundin P, Löfgren L, Stenlöf K, Lam YY, Fagerberg B, Carlsson B. Obesity (Silver Spring). 2011 Nov;19(11):2280-2. doi: 10.1038/oby.2011.251. Epub 2011 Aug 18. Intestinal permeability is associated with visceral adiposity in healthy women.

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Interesting reason why you may gain fat around your waist.

Posted by on 1:35 pm BMJ Formula, Body fat, Eating, Exercise, Fat, Inflammation, Intensity Training, Waist circumference, Weight, Weight loss | 0 comments

Woman's fingers measuring her belly fatWhen you notice that you have gained fat around your waist, it usually also means that you have gained visceral fat.

Visceral fat is fat deposited around your inner organs, and is contributing to metabolic dysfunction and inflammation.

The reviewed research is very interesting because it investigated if there was a connection between an increase in waist circumference, visceral fat, and increased intestinal permeability (Gummesson A, et al. 2011). Intestinal permeability is a way to tell if we are absorbing particles into the blood that were not meant to be absorbed. The mucosal membranes of the intestinal tract are supposed to protect us from absorbing pathogens like bacteria’s and also large protein particles that were not meant to be absorbed. Our body will attempt to defend itself by triggering inflammation when we absorb particles that we are not meant to absorb.

 In this study, waist circumference and intestinal permeability were measured, and computed tomography and dual energy X-Ray were also used. A positive correlation was found between waist circumference and intestinal permeability. Visceral fat and liver fat also correlated with increased intestinal permeability.

It is important to have normal intestinal permeability and a well functioning gastrointestinal tract for many reasons, and it may also help you in keeping your waist slim.

Click here to learn how to eat to support a healthy gastrointestinal tract.

Gummesson A1, Carlsson LM, Storlien LH, Bäckhed F, Lundin P, Löfgren L, Stenlöf K, Lam YY, Fagerberg B, Carlsson B. Intestinal permeability is associated with visceral adiposity in healthy women. Obesity (Silver Spring). 2011 Nov;19(11):2280-2. doi: 10.1038/oby.2011.251. Epub 2011 Aug 18.

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Not all exercise burns fat equally.

Posted by on 11:01 am BMJ Formula, Body fat, Eating, Exercise, Get in shape, Intensity Training, Weight, Weight loss | 0 comments

Gym CyclingHave you accepted this truism: that the more physically active you are, the less likely you are to gain weight? Here is the catch: not all exercise is equally effective when it comes to burning fat. The good news is you don’t have to exercise for several hours a day to make a difference.

The reviewed research is very interesting and the results may surprise you. Healthy young men were divided into three groups: one control group did not exercise, one group did moderate intensity exercise at 50 percent Vo2peak for 60 minutes, and one group did high intensity exercise, alternating 2 minutes at 90 percent Vo2peak with 2 minutes at 25 percent Vo2peak(Trombold JR, et al. 2013). The energy expenditure was the same for both exercise groups.

The participants were provided a test meal the morning after the exercises. Tests were performed fasting before the meal, and 2, 4, and 6 hours after the meal.

The results showed that even if the participant had similar energy expenditures the high intensity exercise was more effective in lowering triglycerides after the meal. The high intensity was also more effective in increasing fat oxidation which means the high intensity exercise burned more fat.

 

 

 

Trombold JR, Christmas KM, Machin DR, Kim IY, Coyle EF Acute high-intensity endurance exercise is more effective than moderate-intensity exercise for attenuation of postprandial triglyceride elevation. J Appl Physiol (1985). 2013 Mar 15;114(6):792-800. doi: 10.1152/japplphysiol.01028.2012. Epub 2013 Jan 31.

Walk fast to get help with with weight loss.

Posted by on 1:00 pm BMI, BMJ Formula, Body fat, Body mass index, Exercise, Exercise, Get in shape, Lose fat, Sports performance, Vigorous Activity, Waist circumference, Weight, Weight loss | 0 comments

Running on treadmillWalking has been promoted as an easy way to lose weight and stay in shape, but is it really effective? That is exactly what the reviewed researched investigated.

The participants a total of 4511 adults aged 18-64 years were included in the study(Fan JX, et al. 2013). The body mass index (BMI) were measured and accelerometers were used to evaluate minutes per day of high intensity bouts of walking of either 10 minutes or more, or less than 10 minutes. This was compared with lower intensity walking of 10 minutes or more per day and lower intensity walking of less than 10 minutes per day.

It was found that both higher intensity short-duration or walking long-duration were related to reduced BMI or risk of overweight/obesity. Neither the short walks or the long walks of lower intensity were found to have a positive effect on BMI or risk of overweight/obesity.

The message is that even less than 10 minutes of walking per day can help you prevent weight gain if it is high intensity walking. This is another example showing that it is the intensity of the exercise you do that is important, not the time you spend doing it. The more intense you exercise, the less time you need to spend doing it.

 

 

 

Fan JX, Brown BB, Hanson H, Kowaleski-Jones L, Smith KR, Zick CD Moderate to vigorous physical activity and weight outcomes: does every minute count? Am J Health Promot. 2013 Sep-Oct;28(1):41-9. doi: 10.4278/ajhp.120606-QUAL-286. Epub 2013 Mar 4.

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