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Your Road to Wellness

Stress

Oxidative stress is involved in cognitive impairment and Alzheimer’s Disease

Posted by on 8:28 am Alzheimer’s, Anti-Aging, Cognition, Diseases, General Health, Health Risk, Research, Stress, Wellness | 0 comments

Increased oxidative stress has been documented in the frontal cortex in individuals with Alzheimer’s disease and in patients with mild cognitive impairment (Ansari, MA 2010).  One of the emerging causative factors associated with Alzheimer’s pathology is oxidative stress. This AD-related increase in oxidative stress has been attributed to decreased levels of the brain antioxidant, glutathione (Saharan and Mandal, 2014). 

The body uses antioxidants to limit the damage done by oxidative stress and glutathione is the body’s most effective self-made antioxidant.  Glutathione is a part of the body’s natural defense against free radical damage.

The following study used proton magnetic resonance spectroscopy to measure glutathione levels in both healthy individuals and patients with alzheimer’s disease (Mandal PK et. al, 2015).

The researchers found a reduction of glutathione in both the hippocampus and frontal cortex–which are two different areas of the brain–in Alzheimer’s patients.  It is interesting to note that glutathione reduction in those regions correlated with a decline in cognitive function.  The researchers concluded that the study provides compelling evidence that the glutathione levels in specific brain regions are relevant markers for mild cognitive impairment and Alzheimer’s disease.  

So how can we ensure that our glutathione levels remain at healthy levels?  One way is to add it into our daily routine via supplementation.  It is now possible to supply glutathione in a bioavailable form–which gets it into the cells where it is needed–and that is by using S-Acetyl Glutathione (Cacciatore et. al., 2010).

The body is making less glutathione as we get older, that happens to everybody, but some are making less than others.

References

Ansari, A, and S W Scheff. “Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex.OUP Academic, Journal of Neuropathology and Experimental Neurology , 1 Feb. 2010, academic.oup.com/jnen/article/69/2/155/2917186.

Cacciatore I1, Cornacchia C, Pinnen F, Mollica A, Di Stefano A. “Prodrug approach for increasing cellular glutathione levels.” Molecules, 3 Mar. 2010, https://www.mdpi.com/1420-3049/15/3/1242

Mandal PK, Saharan S., Tripathi M., and Murari G. “Brain glutathione levels–a novel biomarker for mild cognitive impairment and Alzheimer’s disease.” Biol Psychiatry, 15 Nov. 2015,  https://www.sciencedirect.com/ science/article/pii/S0006322315003121

Saharan S., Mandal P.K., “The emerging role of glutathione in Alzheimer’s disease.” J Alzheimers Dis. 23 April 2014. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad132483

 

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

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Are you stressed? It may affect your gastrointestinal tract.

Posted by on 9:53 am Stress | 0 comments

The gastrointestinal system and the immune system are particularly affected by stress.

We have also known for some time now that that the gastrointestinal tract affects the nervous system and the brain.

A certain type of white blood cells (called mast cells) are especially important, because they release many neurotransmitters and also pro-inflammatory cytokines when they receive stress signals (Konturek PC, et al. 2011).

This will then affect many functions of the gastrointestinal tract.

One of the things affected is the health of the bacterial flora. The bacterial flora is again affecting the nervous system and the brain, which may even affect your mood.

As we learn more about these connections, the gastrointestinal tract has been called the second brain.

There are many ways to treat gastrointestinal dysfunction since the severity and the symptoms can be many.

There are, however, certain things that almost always will make sense and be beneficial. One thing that could be very helpful is to develop more resistance to stress, I am sure you already guessed that, since stress has such far reaching effects. Another thing that can also be helpful is to take an effective probiotic formula to help reduce so-called bad bacteria and help the good ones.

A formula that reduces irritation of the mucosal membranes, and help reduce inflammation would also make sense and be helpful.

Konturek PC1, Brzozowski T, Konturek SJ. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol. 2011 Dec;62(6):591-9.

From Stressed to Relaxed in 60 Seconds

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The probiotic formula with Saccharomyces boulardii has shown to exert an anti-inflammatory effect on intestinal epithelial cells (Sougioultzis S, et al. 2006).

Saccharomyces has shown to significantly reduce the frequency and duration of acute diarrhea in children (Billoo AG, et al. 2006. Kurugol Z, et al. 2005). 

There is evidence that Saccharomyces reduces the risk of antibiotic-associated diarrhoea in children (Kotowska M, et al. 2005).

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How psychological hardiness and resilience affects cardiovascular risk?

Posted by on 9:52 am Stress | 0 comments

Stress does not affect everybody the same.

Most people don’t feel good when they are exposed to stress, and experience a decline in their health and performance.

However, not everybody will experience these negative effects of stress.

In this research psychological hardiness and resilience, and it’s effect on cardiovascular risk factors were investigated (Batone PT, et al. 2016).

The participants were 338 middle-aged adults and these were the results.

High hardiness was related to higher high density lipoprotein (HDL)  and less body fat.

High HDL levels are considered to be protective against cardiovascular disease.

Lower hardiness was associated with higher total cholesterol to HDL ratio which is a risk factor for cardiovascular disease.

Even if we are exposed to more stress at certain times, stress is a part of life.

Knowing that, it makes sense to do what you can to be more stress resistant.

The good news is that you can learn to be more stress resistant.

One way is to start to meditate regularly.

When you have an effective and well proven method, it’s just a matter of practice.

It’s well worth it.

 

Bartone PT1,2, Valdes JJ1, Sandvik A3,4. Psychological hardiness predicts cardiovascular health. Psychol Health Med. 2016 Sep;21(6):743-9. doi: 10.1080/13548506.2015.1120323. Epub 2015 Dec 11.

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From Stressed to Relaxed in 60 Seconds

You will learn: 

  • How to implement acupuncture knowledge and affect the vagus nerve in seconds. 
  • What to do to literally feel more relaxed and also feel less pain and stiffness in your neck in just 60 seconds

  How to create lasting results and be more stress resistant.

  • How to train your mind so you are in control of how you feel instead of letting other people or situations control you.

 

 Buy Here

Stress can counteract benefits of healthy meals.

Posted by on 9:45 am Stress | 0 comments

Depression, stress and diet can all affect inflammation, but who would have known that stress could alter the effect of a meal.

In a double-blind, randomized, crossover study, 58 healthy women had 4 inflammatory markers tested (Kiecolt-Glaser JK, et al. 2016).

During 2 separate admissions of 9.5 hours, they received either a high saturated fat meal or a meal low in saturated fat.

After the high saturated fat meal, the women’s inflammatory markers increased compared to the low saturated fat meal.

It can be interesting in itself that the women reacted with an inflammatory response after they ate a meal high in saturated fat, but here is the real interesting thing.

When the women had been exposed to stressors the prior day, they also reacted with increased inflammation to the low saturated fat meal.

Stress, in other words, turned a meal which normally did not result in an inflammatory response into an inflammatory meal.

Can you imagine what happens if you feel stressed all day long?

It is not only unpleasant, but extremely unhealthy. This was only one example of that.

Stress is a part of life and is hard to avoid. The real solution is to be stress resistant. This can be learned by practice.

Meditation when used with other specific tools, is a way to improve your stress resistance.

Kiecolt-Glaser JK1,2, Fagundes CP3,4, Andridge R5, Peng J6, Malarkey WB1,7, Habash D8, Belury MA1,9. Depression, daily stressors and inflammatory responses to high-fat meals: when stress overrides healthier food choices. Mol Psychiatry. 2016 Sep 20. doi: 10.1038/mp.2016.149. [Epub ahead of print]

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From Stressed to Relaxed in 60 Seconds

You will learn: 

  • How to implement acupuncture knowledge and affect the vagus nerve in seconds. 
  • What to do to literally feel more relaxed and also feel less pain and stiffness in your neck in just 60 seconds

  How to create lasting results and be more stress resistant.

  • How to train your mind so you are in control of how you feel instead of letting other people or situations control you.

 

 Buy Here

Stress can store fat around your waist. This is why.

Posted by on 8:35 am Stress | 0 comments

We are used to thinking of all stress as being harmful, but that is not the case.

The acute stress response is beneficial.

The acute stress response is designed to provide us with extra energy when we need it the most, when our life is in danger, and we need to defend our self or escape.

For example, exercise is stressful, but that’s why it provides benefits.

We adapt to the stress and improve cardiovascular fitness and strength depending on how we exercise.

Chronic stress, however, is detrimental, that’s what we need to get a handle on.

It has been known for a long time that uncontrollable stress is associated with abdominal fat deposits (Moyer AE, et al.1994).

When women were exposed to stressful situations, it was found that the women with a high waist to hip ratio secreted significantly more of the hormone cortisol than the women with a lower waist to hip ratio.

A Higher waist to hip ratio was also associated with poorer coping skills.

Women exposed to stressful laboratory sessions over 4 days showed that the women with a high waist to hip ratio found these tests more threatening, performed more poorly, reported more chronic stress and secreted more cortisol (Epel ES, et al. 2000).

Lean women, but with a high waist to hip ratio, secreted significantly more cortisol than lean women with a low hip to waist ratio in response to familiar stress challenges.

If you have a difficult time losing weight around your waist, it may be because of stress and increased cortisol secretion.

The solution is to get more stress resistant, so stress does not have the same impact on you.

This can be learned.

There are several ways to deal with this, meditation is one way.

Epel ES1, McEwen B, Seeman T, Matthews K, Castellazzo G, Brownell KD, Bell J, Ickovics JR. Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat. Psychosom Med. 2000 Sep-Oct;62(5):623-32.
Moyer AE1, Rodin J, Grilo CM, Cummings N, Larson LM, Rebuffé-Scrive M. Stress-induced cortisol response and fat distribution in women. Obes Res. 1994 May;2(3):255-62.

stress picture 3

From Stressed to Relaxed in 60 Seconds

You will learn: 

  • How to implement acupuncture knowledge and affect the vagus nerve in seconds. 
  • What to do to literally feel more relaxed and also feel less pain and stiffness in your neck in just 60 seconds

  How to create lasting results and be more stress resistant.

  • How to train your mind so you are in control of how you feel instead of letting other people or situations control you.

 

 Buy Here

 

 

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Less stressed in 60 seconds.

Posted by on 12:45 pm Stress | 0 comments


Stress is causing anxiety and tension, and who likes that.

Would it not be nice if you could reduce both anxiety and tension quickly when you need to?

There is research showing that pressure on certain areas(points on the ear) will reduce anxiety (Kober A, et al. 2003). Patients who required ambulance transport to the hospital for a medical condition were randomized into either a group receiving pressure on a specific relaxation point on the ear, or a placebo group where the pressure was applied to a non-related area. Both groups were evaluated for anxiety.

The patients who were treated using the relaxation point reported significantly less anxiety than the patients in the placebo group.

This is not the only study documenting the same results.

100 elderly patients transported to the hospital with kidney stones were divided into a treatment group receiving pressure on relaxation points on the ear, or a placebo group receiving pressure on non-related points (Mora B, et al. 2007).

The conclusion of the research was that this was an effective treatment for anxiety.

This can be a handy tool and you can easily do it yourself without having to rely on somebody else to do it for you.

That makes it even more practical.

Kober A1, Scheck T, Schubert B, Strasser H, Gustorff B, Bertalanffy P, Wang SM, Kain ZN, Hoerauf K. Auricular acupressure as a treatment for anxiety in prehospital transport settings. Anesthesiology. 2003 Jun;98(6):1328-32.
Mora B1, Iannuzzi M, Lang T, Steinlechner B, Barker R, Dobrovits M, Wimmer C, Kober A. Auricular acupressure as a treatment for anxiety before extracorporeal shock wave lithotripsy in the elderly. J Urol. 2007 Jul;178(1):160-4; discussion 164. Epub 2007 May 17.

 

stress picture 3

From Stressed to Relaxed in 60 Seconds

You will learn: 

  • How to implement acupuncture knowledge and affect the vagus nerve in seconds. 
  • What to do to literally feel more relaxed and also feel less pain and stiffness in your neck in just 60 seconds

 While this is exciting, this program is much more.  Illusion of Mind

You will also learn:

  • How to create lasting results and be more stress resistant.
  • How to train your mind so you are in control of how you feel instead of letting other people or situations control you.

 

 Buy Here