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Joint health

This mineral can influence muscle strength, be sure you get enough of it!

Posted by on 9:15 am BMJ Formula, BMJ Formula, General Health, Intensity Training, Joint health, magnesium, Muscles, Supplements | 0 comments

This mineral can influence muscle strength, be sure you get enough of it!

 

 

We lose minerals when we perspire. Hot weather and exercise will for that reason make us lose
more.

Some minerals are also more important than others. Magnesium is one of the most important
ones and many people don’t get enough of it.

Magnesium is involved in energy metabolism and numerous enzymatic reactions.

 

 

Athletes often don’t get enough magnesium to compensate for what they lose. This study investigated the impact magnesium can have on muscle strength in elite male
basketball, handball, and volleyball players (Santos DA, et. al, 2011).

It was found that the intake of magnesium was directly associated with maximal isometric
trunk flexion, rotation, and handgrip strength.

Magnesium does not only work for athletes.
The following research included 1138 men and women with an average age of 66.7 years
(Dominguez LJ, et.al., 2006).

The participants were evaluated by testing grip strength, lower-leg muscle power, knee
extension torque, and ankle extension isometric strength.

The researchers found that blood levels of magnesium were significantly associated with
muscle strength and performance as evaluated with the above tests.

 

strength

 

Magnesium in the form of an amino acid chelate is a good choice since it is both well tolerated
and better absorbed than the more common form of magnesium oxide which can cause GI
irritation.

References:

Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM,
Ferrucci L. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J
Clin Nutr. 2006 Aug;84(2):419-26.
Santos DA, Matias CN, Monteiro CP, Silva AM, Rocha PM, Minderico CS, Bettencourt Sardinha
L, Laires MJ. Magnesium intake is associated with strength performance in elite basketball,
handball and volleyball players. Magnes Res. 2011 Dec;24(4):215-9.

 

BMJ

 

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BMJ Bones, Muscles, and Joints

 

 

 

 

Antioxidants in joint fluid are reduced in osteoarthritis. This is what you can do.

Posted by on 6:50 am Antioxidents, Arthritis, BMJ Formula, Exercise, Joint health, Supplements, Supplements for Conditions, Supplements List | 0 comments

Excess reactive oxygen species and oxidative damage have been associated with the pathogenesis of osteoarthritis.  Joint fluid from patients with osteoarthritis is characterized by significantly decreased extracellular superoxide dismutase (SOD) levels, a significantly decreased glutathione level, and ascorbate when compared to knee joints with intact cartilage (Regan EA, et.al., 2008).

SOD is one of the body’s antioxidant enzymes and glutathione is the body’s most effective antioxidant.  These changes in joint fluid antioxidants are likely to accelerate the oxidative damage of the cartilage.

The body needs copper, zinc, and manganese to produce SOD, so one of the things you can do to help prevent cartilage degeneration is to take these minerals.  The glutathione level was also reduced, and you can also take S-Acetyl Glutathione to increase cellular glutathione (Cacciatore I, et.al., 2010).

Don’t make the mistake and supplement with reduced glutathione which is the most common form on the market.  No significant changes were observed in biomarkers of oxidative stress, including glutathione status of oral glutathione supplementation (Allen J, Bradley RD, 2011).

References

Allen J, Bradley RD.Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. J Altern Complement Med. 2011 Sep;17(9):827-33.

Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A. Prodrug approach for increasing cellular glutathione levels. Molecules. 2010 Mar 3;15(3):1242-64.

Regan EA, Bowler RP, Crapo JD.Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injuryOsteoarthritis Cartilage. 2008 Apr;16(4):515-21.

 

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

BioPro, Inc. Tissue Recovery is using the patented form of S-Acetyl Glutathione from the Italian company that has the patent for S-Acetyl Glutathione.

Click here to get your bottle of the most effective form of glutathione!

 

 

 

 

 

You may know that you need calcium, but maybe you have heard that taking calcium may cause calcification of blood vessels.

Taking calcium by itself is not a good idea. You need to take calcium in a formula that includes multiple nutrients, and it needs to include magnesium. That’s one of the reasons the BMJ contains a large amount of magnesium in a very well absorbed form.

Click here to improve your bone, muscle, and joint health!

How to protect the cartilage of your joints from oxidative stress and degeneration.

Posted by on 10:02 am Health, Joint health | 0 comments

Oxidative stress tends to increase as we get older and contributes to cell death of cartilage. It also damages other tissue. This leads to increased cartilage degeneration, which can lead to arthritis, and you don’t want to get arthritis.

In the following study, the researchers took samples of cartilage cells–which are called chondrocytes–isolated from the articular cartilage of young and older adult human tissue donors (Carlo MD Jr, Loeser RF, 2003).

These cells were then exposed to oxidative stress. Twice as many chondrocytes died from donors 50 years or older compared to those derived from 18-49 years old donors.

The researchers found that cells depleted of intracellular glutathione were more susceptible to cell death when exposed to oxidative stress.

They concluded that this may represent an important contributing factor to the development of osteoarthritis in older adults.

The most common form of glutathione is not well absorbed; most of it is oxidized in the stomach.

The good news is that you now can take an effective form of glutathione called S-Acetyl Glutathione, a patented form of glutathione shown to get into the cells which need protection from oxidative stress (Cacciatore I, et al. 2010).

References

Carlo MD Jr, Loeser RF, Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels.Arthritis Rheum. 2003 Dec;48(12):3419-30.

Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A. Prodrug approach for increasing cellular glutathione levelsMolecules. 2010 Mar 3;15(3):1242-64

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

BioPro, Inc. Tissue Recovery is using the patented form of S-Acetyl Glutathione from the Italian company that has the patent for S-Acetyl Glutathione.

Click here to get your bottle of the most effective form of glutathione!

Research indicates that this natural substance can help osteoarthritis.

Posted by on 9:00 am Joint health | 0 comments

We used to believe that inflammation was not a factor in osteoarthritis.

This has, however, been proven to be wrong.

Inflammation has a catabolic effect on cartilage(it causes cartilage damage).

Whatever we can do to reduce excessive inflammation would help to reduce the symptoms of osteoarthritis.

What you eat on a daily basis is very important, but even if you eat well, some extra help with lowering inflammation is still a good idea since inflammation tends to increase as we get older.

Curcumin, the active ingredient of turmeric, can be that help.

Research has shown that curcumin protects human chondrocytes (cartilage cells) from the catabolic actions of IL-1beta an inflammatory cytokine (Henrotin Y, et al. 2010).

It also provides protection against MMP-3 up-regulation.

MMp-3 is an enzyme causing degradation of cartilage.

An abnormal increase in the activity of MMP-3 can contribute to cartilage degeneration, while a normal activity will help to keep the cartilage healthy, only removing damaged cells.

It makes sense to take curcumin, there is only one problem.

Regular curcumin is not well absorbed, making it impractical to use.

That issue has now been resolved.

There are several ways to make curcumin better absorbed, but they are not all equally good.

One way is to combine it with a black pepper extract which inhibits a secondary detox pathway of the liver, so it stays in the body longer.

I don’t think that’s a good idea because it also makes everything else which is detoxified through that pathway stay in the body longer.

I think we should rather assist the body in it’s attempt to detoxify.

It makes more sense to use a product which is absorbed better by other means.

Henrotin Y1, Clutterbuck AL, Allaway D, Lodwig EM, Harris P, Mathy-Hartert M, Shakibaei M, Mobasheri A. Biological actions of curcumin on articular chondrocytes. Osteoarthritis Cartilage. 2010 Feb;18(2):141-9. doi: 10.1016/j.joca.2009.10.002. Epub 2009 Oct 8.

 

Better Curcumin

IMG_11002Research has documented the many benefits of curcumin (found in turmeric spice), but regular turmeric is hard to absorb. The type of curcumin in our formula improves the absorption 6.93 fold compared to regular curcumin (Anthony B, et al. 2008).

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This is important for your joints.

Posted by on 7:56 am Joint health | 0 comments

Magnesium is usually not what we think of when it comes to joint health and osteoarthritis.

Magnesium is, however, also affecting the health of your joints.

Research indicates that magnesium affects several pathways that have been implicated in osteoarthritis, including inflammatory mediators, cartilage damage, and defective chondrocyte biosynthesis, among other things (Li Y, et al. 2016).

In one study including 2,855 participants, serum magnesium concentration was measured and radiographic osteoarthritic changes were evaluated (Zeng C., et al. 2015). The results showed a significant association between serum magnesium levels and osteoarthritis. The participants with higher magnesium levels had less osteoarthritis.

Magnesium is involved in 300 enzymatic reactions in the body and even affects the health of your joints.

Just remember that it is better to take magnesium with other important minerals since minerals tend to affect each other.

If you only take one mineral at a time, you may decrease the level of another one.

Something else to keep in mind is that the minerals zinc, copper and manganese are also important to keep your cartilage healthy.

To avoid gastrointestinal irritation and improve the absorption, magnesium in the form of an amino acid chelate is the preference.

 

Li Y1, Yue J1, Yang C2. Unraveling the role of Mg(++) in osteoarthritis. Life Sci. 2016 Feb 15;147:24-9. doi: 10.1016/j.lfs.2016.01.029. Epub 2016 Jan 19.
Zeng C1, Wei J1, Li H1, Yang T1, Zhang FJ1, Pan D1, Xiao YB1, Yang TB1, Lei GH2. Relationship between Serum Magnesium Concentration and Radiographic Knee Osteoarthritis. J Rheumatol. 2015 Jul;42(7):1231-6. doi: 10.3899/jrheum.141414. Epub 2015 Jun 1.

 

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