Your Road to Wellness

Eating

What’s important for the cardiovascular system is also important for the immune system.

Posted by on 9:00 am BMI, Body fat, Body mass index, Cardiovascular Disease, Cardiovascular disease & waist-hip ratio, Diet, Eating, General Health, Health Risk, Inflammation, Weight, Weight loss | 0 comments

obese man with burgers

 

In this study, participants taking berberine when compared to the placebo group saw a
reduction in triglycerides by 35.9% total cholesterol by 18.1% and LDL (low-density lipoprotein),
the so-called bad cholesterol by 21.1% (Zhang Y, et.al., 2008).

Patients with metabolic syndrome treated with berberine for 3 months showed a decrease in
their BMI (body mass index) from 31.5 to 27.4 in this study (Yang J, et.al., 2012).
Patients diagnosed with the metabolic syndrome usually have several symptoms, they are
insulin resistant, have increased waist circumference and high blood pressure.
The same research also showed that berberine decreased leptin levels from 8.01 to 5.12 μg/L.
Leptin is a hormone that suppresses food intake and induces weight loss. Obese patients are
usually leptin-resistant.

 

 

When 10 studies were reviewed both BMI and waist circumference decreased in participants
taking berberine (Xiong P, et.al.,2020).

It is important to produce a balanced immune response when needed.
An overreaction of the immune system will cause damage and is harmful. It can actually kill us.
Some people are killed by an overreaction of their immune system, not from the invading virus
or bacteria.

This research showed that berberine had an anti-inflammatory effect and initiated a more
balanced immune response (Kalmarzi RN, et.al.,2019).
Inflammation is also a risk factor for cardiovascular disease.

When researchers treated patients with the acute coronary syndrome with berberine, they found
that several inflammatory markers were reduced, C-reactive protein and interleukin-6 were 2 of
them (Meng S, et.al., 2012).

Berberine has shown to be a very useful plant-derived compound benefitting important
functions from blood glucose metabolism, cardiovascular function, fat storage, immune
system and inflammation.

These functions are interconnected, that is why berberine is such a valuable substance.

 

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References:

Kalmarzi RN, Naleini SN, Ashtary-Larky D, Peluso I, Jouybari L, Rafi A, Ghorat F, Heidari N,
Sharifian F, Mardaneh J, Aiello P4, Helbi S, Kooti W.Anti-Inflammatory and Immunomodulatory
Effects of Barberry ( Berberis vulgaris ) and Its Main Compounds.Oxid Med Cell Longev. 2019
Nov 19;2019:6183965.

Meng S, Wang LS, Huang ZQ, Zhou Q, Sun YG, Cao JT, Li YG, Wang CQ. Berberine
ameliorates inflammation in patients with acute coronary syndrome following percutaneous
coronary intervention. Clin Exp Pharmacol Physiol. 2012 May;39(5):406-11.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Berberine improves insulin sensitivity by
inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic
syndrome patients. Evid Based Complement Alternat Med. 2012;2012:363845

Xiong P, Niu L, Talaei S, Kord-Varkaneh H, Clark CCT, Găman MA, Rahmani J, Dorosti M,
Mousavi SM, Zarezadeh M, Taghizade-Bilondi H, Zhang J. The effect of berberine
supplementation on obesity indices: A dose- response meta-analysis and systematic review of
randomized controlled trials. Complement Ther Clin Pract. 2020 May;39:101113.

 

glucose metabolism supportThis formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

👉🏻 BUY NOW 👈🏻

2 important things to help you stay healthy and feel good.

Posted by on 9:00 am Diabetes, Diet, Eating, Energy, Health, Health Risk, Inflammation, Inflammatory factor, Low glycemic meals, Stay healthy, Supplements, Supplements for Conditions, Supplements List, Type 1 diabetes, Type 2 diabetes | 0 comments

blood glucose food

 

You need to keep your glucose metabolism healthy by keeping your blood glucose at a low and
normal level.
There are several reasons why this is important. When your blood glucose is elevated to a high
level as it tends to be when we get insulin resistant, and when we eat high glycemic index food,
we usually get tired.
Elevated blood glucose also leads to increased low-grade inflammation, and inflammation is the
the second thing you need to keep low to stay healthy.
Increasing CRP, an inflammatory marker, has been found with higher fasting glucose levels,
even among subjects with fasting glucose in the normal range (Aronson D. et.al., 2004).

 

 

Eating high nutrient, low glycemic index meals are important, and so is exercise.
There is however something else you also can do to keep your blood glucose lower.
You can take berberine, a natural plant derivative.
Berberine has shown to provide several health benefits. One of them is keeping the blood
glucose at a lower, normal level.

In the following study participants with type 2 diabetes were randomized to take either berberine
or metformin (a diabetic medication) for 3 months (Yin J, et.al., 2008).
The effect of berberine was found to be similar to metformin.
A significant decrease in hemoglobin A1c from 9.5% to 7.5% was found when taking berberine.
Hemoglobin A1c is a measurement of long term glucose control.
Fasting blood glucose was reduced with 34.9%, postprandial blood glucose with 43.9%, and
plasma triglycerides with 21.2%. Postprandial glucose is the blood glucose measured after a
meal.
The insulin resistance index was reduced by 44.7%.
Another study which included 116 patients also with type 2 diabetes showed similar results
(Zhang Y, et.al., 2008).
In these studies, the participants had type 2 diabetes which means they were severely insulin
resistant.
There is no reason to wait until we get a serious disease before taking action.
Berberine can be used to help keep glucose metabolism healthy.

 

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References

Aronson D, Bartha P, Zinder O, Kerner A, Shitman E, Markiewicz W, Brook GJ, Levy
Y. Association between fasting glucose and C-reactive protein in middle-aged subjects.
Diabet Med. 2004 Jan;21(1):39-44.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism.
2008 May;57(5):712-7. doi: 10.1016/j.metabol.2008.01.013.

glucose metabolism support

This formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

👉🏻 BUY NOW 👈🏻

How can irregular eating affect us?

Posted by on 9:00 am Diet, Eating | 0 comments

 

We know that eating more for breakfast and less for dinner can result in weight loss.
Eating dinner earlier can also lead to weight loss.
How might an irregular eating pattern affect us?
This has been investigated.
In this study, participants followed either a regular meal pattern (6 meals daily) or an irregular
meal pattern (3-9 meals daily) (Alhussain MH, et.al., 2016).
After 14 days the alternative meal pattern was followed.
Before and after each period when the participants were fasting, and also for 3 hours after
intake of a test drink, the participants were measured for energy expenditure, circulating glucose
and several other factors.
The researchers found that a regular eating pattern was associated with an increased
thermic food effect, which means they were burning more calories.
The regular eating pattern was also associated with a lower glucose response and less
hunger.

 

 

It does not take very long before the adverse effects of a misalignment of the circadian rhythm are
noticed.
This research showed that after only 3 days, increases in blood pressure and several
inflammatory markers were measured (Morris CJ, et.al., 2016).

References:

Alhussain MH, Macdonald IA, Taylor MA. Irregular meal-pattern effects on energy expenditure,
metabolism, and appetite regulation: a randomized controlled trial in healthy normal-weight
women. Am J Clin Nutr. 2016 Jul;104(1):21-32.

Morris CJ, Purvis TE, Hu K, Scheer FA. Circadian misalignment increases cardiovascular
disease risk factors in humans. Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1402-11 .

When is it easier for your body to transfer blood glucose from a meal into your cells?

Posted by on 9:00 am Bloodsugar, Eating, Glucose, High glycemic index | 0 comments

glucose level

 

We know it’s better to avoid high blood glucose levels since that can cause tissue damage.

Several things can affect blood glucose levels, one important factor is the type of food we eat.

 

It’s logical that the food we eat will have an impact on our blood glucose level, but can it also make a difference when we eat?

Yes, it can make a difference. Research has shown that the circadian rhythm which is affected by the light cycle regulates glucose, lipid, and energy metabolism in humans (Poggiogalle E, et.al., 2018).

 

 

We have known for many years that the body metabolizes glucose differently in the morning compared to the evening.

When the participants of this study received three oral glucose tolerance tests, one in the morning, one in the afternoon, and one in the evening on separate days, this is what the researchers found (Jarrett RJ, et.al., 1972).

The average blood sugar levels in the afternoon and evening tests were similar, but they were both significantly higher than those in the morning test.

 

For somebody who already has a tendency to have high blood glucose levels, it’s even more important to take this into consideration when eating.

These researchers found that glycemic control was dramatically impaired in the evening in people with prediabetes (Sonnier T, et.al., 2014).

 

glycemic index

 

Most people would benefit by keeping this in mind when eating.

We will usually metabolize a meal better and keep the blood glucose levels lower in the morning.

This is one of the reasons why it’s better to eat more in the morning and less in the evening.

 

References:

 

Jarrett RJ, Baker IA, Keen H, Oakley NW..Diurnal variation in oral glucose tolerance: blood sugar and plasma insulin levels morning, afternoon, and evening.Br Med J. 1972 Jan 22;1(5794):199-201.

 

Poggiogalle E, Jamshed H, Peterson CM.Circadian regulation of glucose, lipid, and energy metabolism in humans.Metabolism. 2018 Jul;84:11-27.

 

Sonnier T, Rood J, Gimble JM, Peterson CM.Glycemic control is impaired in the evening in prediabetes through multiple diurnal rhythms. J Diabetes Complications. 2014 Nov-Dec;28(6):836-43.

Why you don’t want to eat food that results in high blood glucose levels?

Posted by on 9:00 am Bloodsugar, Diet, Eating | 0 comments

low glycemic food

 

We know that diabetes can lead to serious complications because of elevated blood glucose
levels.
We don’t, however, have to be diagnosed with diabetes to be exposed to the negative effects of
elevated blood glucose.
What is called protein glycation and formation of advanced glycation end products play an
an important role in diabetic complications like retinopathy, nephropathy, neuropathy and
cardiomyopathy and also other diseases like rheumatoid arthritis, osteoporosis, and aging
(Singh VP, et.al., 2014).

 

 

Glycation of proteins takes place when glucose reacts with proteins because it is
causing damage.
Advanced glycation end products, is formed when we have high blood glucose levels and is
causing inflammation and endothelial damage (de Vries MA, et.al., 2014).
The endothelium is the inner layer of the blood vessel wall.
Eating food with a high glycemic index leads to the quick and high elevation of your blood glucose.
This results in acute inflammation causing endothelial dysfunction which may be one of the
earliest events forming atherosclerosis.
Processed food, bread, cookies, candy, and ice cream are some examples of high glycemic
index food.

 

glycemic index

A plant-based diet tends to have a lower glycemic index if you are careful with potatoes,
processed grains, and very sweet fruit. Beans and lentils are examples of lower glycemic index
carbohydrates which will also lower the glycemic index of a meal since they slow down the
absorption of the glucose from grains.

 

References:

de Vries MA, Klop B, Janssen HW, Njo TL, Westerman EM, Castro Cabezas M. Postprandial
inflammation: targeting glucose and lipids. Adv Exp Med Biol. 2014;824:161-70.
Singh VP, Bali A, Singh N, Jaggi AS. Advanced glycation end products and diabetic
complications. Korean J Physiol Pharmacol. 2014 Feb;18(1):1-14.

How to reduce your blood pressure by eating earlier

Posted by on 8:00 am Blood Pressure, Eating | 0 comments

blood pressure

 

Maybe you find it surprising that you can reduce your blood pressure just by changing the time
you eat. You can however not only reduce your blood pressure by doing that, but quite a few
other things have been shown to improve as well.
This research was based on the results of intermittent fasting.
The study was small, but it was very well controlled (Sutton EF, et.al., 2018).
Prediabetic men were randomized to time-restricted feeding, which in this case meant a 6 hour
feeding period with dinner before 3 p.m., or a control schedule with a 12 hour feeding period.
The participants followed the time-restricted feeding schedule for 5 weeks and were later crossed
over to the other schedule.

 

 

The meals they ingested were prepared for them, and the number of daily calories was
calculated according to their energy expenditure so they would not lose any weight. The
researchers also checked that all of the meals were ingested. The schedules were followed for
5 weeks. The participants had breakfast, lunch and dinner, all within 6 hours, and dinner was no later than 3 p.m.

 

eating schedule

 

On the time-restricted feeding schedule, the participants improved insulin sensitivity, beta
cell responsiveness, blood pressure, oxidative stress, and they felt less hungry.
Beta cells are the insulin-producing cells in the pancreas.
All of these changes were seen from only changing the timing of when they were eating.
Try it and see how it works for you.

 

Reference:

Sutton EF1, Beyl R1, Early KS2, Cefalu WT3, Ravussin E1, Peterson CM , Early Time-Restricted
Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight
Loss in Men with Prediabetes. Cell Metab. 2018 Jun 5;27(6):1212-1221.e3.