Your Road to Wellness

Cervical Cancer

Can you change your estrogen metabolites by exercising?

Posted by on 11:31 pm Breast cancer, Cervical Cancer, Endometrial cancer, Exercise, Exercise, Women, Womens health | 0 comments

Beautiful skinny woman riding a bike in fitnessWhat would be the benefits of changing your estrogen metabolites?
Certain estrogen metabolites are related to a higher risk for estrogen related diseases. Breast cancer is one of those diseases. If you could change the ratio between the harmless metabolites and the ones related to an increased risk for estrogen related problems you would be better off.
The reviewed research investigated if exercise could do that since exercise has shown to reduce the risk for breast cancer.(Smith AJ,et al. 2013).

The participants were healthy young women who were divided into either an exercise group doing 30 minutes of moderate to vigorous aerobic exercise 5 days a week or a sedentary control group.  The study went on for approximately 16 weeks.

Estrogen’s and estrogen metabolites were measured,and the rates of the different metabolites were calculated. The change from the baseline measurements increased significantly in the exercise group for 2-OHE1/16α-OHE1 which is the ratio of the estrogen metabolites associated with a decreased risk for estrogen related diseases. This change was not seen in the control group.
 

The researchers concluded that this may be the mechanism by which increased physical activity is decreasing the risk for breast cancer.

Smith AJ1, Phipps WR, Thomas W, Schmitz KH, Kurzer MS. The effects of aerobic exercise on estrogen metabolism in healthy premenopausal women. Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):756-64. doi: 10.1158/1055-9965.EPI-12-1325.

Do you like hot beverages?

Posted by on 1:05 pm Adult Lukemia, Cervical Cancer, Green tea, Hot Beverages, Human Papilloma Virus | 0 comments

If you do, try green tea!
It is probably the healthiest hot beverage you can drink.

Green tea and especially a constituent of green tea, called epigallocatechin-3-gallate (EGCG) has shown to inhibit cancer growth (Zhang XD, et al. 2008, Ahn WS. et al. 2003). You may have heard that the human papilloma virus has been associated with cervical cancer. Data suggests a possible gene regulatory role of EGCG and the research supports the inhibitory effect of EGCG on cervical cancer cell growth. It has also shown an anti-tumor effect(which slows the growth of tumors).

Not only cervical cancer inhibition has been documented, but a higher consumption of green tea has been associated with a reduced risk of adult leukemia.

So if you enjoy hot beverages, green tea is a great choice. Not only is green tea good hot, but if preferred, it can also be served cold.

Reference:

Zhang XD, et al. A case-control study on green tea consumption and the risk of adult leukemia. Zhonhua Liu Xing Bing Xue Za Zhi. 2008 Mar;29(3):290-3.


Ahn WS, et al. A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis, G(1) arrest, and regulation of gene expression. DNA Cell Biol. 2003 Mar;22(3):217-24.