Your Road to Wellness

Cancer

Why Flaxseeds Have A Beneficial Effect On Breast Cancer Risk

Posted by on Cancer, Diet, Eating, General Health | 0 comments

It’s not because of reduced inflammation.

Adapting habits research has found to be beneficial for reducing cancer risk is a good idea, since your body does not give you any early warning signs.

Pain is not a good indicator for cancer.

Cancer usually takes quite a while to develop, pain occurs later.

We know that low-grade inflammation, the type of inflammation we usually are unaware of increases cancer risk, but what else than reducing inflammation can you do?

You can eat more lignans.

Lignans are plant-derived compounds with anticarcinogenic properties.

Lignans are metabolized to enterolignans, and as such, they have shown to reduce the risk of breast cancer.

Research has documented that patients with breast cancer who have higher enterolactone levels, a marker of dietary lignans, have significantly better survival (Buck K, et.al., 2011). This was for estrogen-receptor negative tumors.

21 studies showed that high lignan exposure was associated with reduced breast cancer risk in postmenopausal women (Buck K. et.al., 2010).

Where do you find high amount of these beneficial lignans?

You find this kind of lignans in flaxseeds.

When patients with breast cancer were given either a daily 25 g of flaxseed-containing muffin or a placebo, a reduction in apoptosis (death of cancer cells) was seen in the flaxseed group, but not in the placebo group (Thomson LU, et.al., 2005).

This was after only 32 days.

Higher intake of dried beans, but not grains, fruit or vegetable also reduced the overall mortality risk somewhat, and the highest lignan intake reduced the risk significantly (McCann SE, et.al., 2010).

I suggest you buy organic flaxseeds and grind 2 tablespoons in a coffee grinder for approximately 15 seconds. Put them in a little bit of water and stir. Do that once or twice daily, and drink it thick. I think they taste good when I do it that way. But, it does not matter how you do it, as long as you ingest them. You can also sprinkle it on food if you prefer that.

Just a simple habit like this may help you stay healthier.


References:

Thompson, L. U., Chen, J. M., Li, T., Strasser-Weippl, K., & Goss, P. E. (2005). Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clinical cancer research11(10), 3828-3835.

McCann, S. E., Thompson, L. U., Nie, J., Dorn, J., Trevisan, M., Shields, P. G., … & Freudenheim, J. L. (2010). Dietary lignan intakes in relation to survival among women with breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study. Breast cancer research and treatment122(1), 229-235.

Buck, K., Zaineddin, A. K., Vrieling, A., Linseisen, J., & Chang-Claude, J. (2010). Meta-analyses of lignans and enterolignans in relation to breast cancer risk. The American journal of clinical nutrition, ajcn-28573.

Buck, K., Vrieling, A., Zaineddin, A. K., Becker, S., Hüsing, A., Kaaks, R., … & Chang-Claude, J. (2011). Serum enterolactone and prognosis of postmenopausal breast cancer. Journal of Clinical Oncology29(28), 3730-3738.

Buck, K., Zaineddin, A. K., Vrieling, A., Heinz, J., Linseisen, J., Flesch-Janys, D., & Chang-Claude, J. (2011). Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer. British journal of cancer105(8), 1151.


Learn To Eat Program:

Recommendations that work. Improve your lifestyle with the food you eat. This is not a regular diet program.

Prostate cancer: The most important foods to avoid.

Posted by on Cancer, Prostate cancer | 0 comments

 

As men get older prostate cancer gets more and more common.

Here are some interesting facts.

After reviewing 13 independent studies, the researchers concluded that the consumption of milk and dairy products increases the risk of prostate cancer (Qin LQ, et al. 2007). Milk stimulated the growth of prostate cancer cells in cell cultures in 14 separate experiments (Tate PL, et al. 2011).

Why would dairy products stimulate prostate cancer?

The kinase mTORC1 which is a regulator of tissue growth and also regulates cell death is stimulated by dairy, and it is upregulated in nearly 100% of advanced prostate cancers (Melnik BC, et al. 2012). It is also another reason and that is hormones which naturally is found in milk.

A study including 47,896 men, the ones with the highest intake of choline, had a 70% increased risk of lethal prostate cancer (Richman EL, et al. 2012).

Where do we find choline?

The foods containing the highest amount of choline are meat, milk and eggs.

 

Learn to Eat:  Recommendations that work. This is not a regular diet program.

 

Melnik BC1, John SM, Carrera-Bastos P, Cordain L. The impact of cow’s milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer. Nutr Metab (Lond). 2012 Aug 14;9(1):74. doi: 10.1186/1743-7075-9-74.
Qin LQ1, Xu JY, Wang PY, Tong J, Hoshi K. Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies. Asia Pac J Clin Nutr. 2007;16(3):467-76.
Richman EL1, Kenfield SA, Stampfer MJ, Giovannucci EL, Zeisel SH, Willett WC, Chan JM. Choline intake and risk of lethal prostate cancer: incidence and survival. Am J Clin Nutr. 2012 Oct;96(4):855-63. Epub 2012 Sep 5.
Tate PL1, Bibb R, Larcom LL. Milk stimulates growth of prostate cancer cells in culture. Nutr Cancer. 2011 Nov;63(8):1361-6. doi: 10.1080/01635581.2011.609306. Epub 2011 Nov 1.

Can exercise on it’s own affect prostate cancer?

Posted by on Cancer, Prostate cancer | 0 comments


We know that exercise, incorporated with a plant based diet and stress management, has a beneficial effect on prostate cancer, but what about exercise on it’s own?

This has now been researched and here are the results.

Patients with recurrence following radical prostatectomy, or patients managed on active surveillance, were either put in a group doing home-based endurance training 3 times per week for 24 months, or a control group receiving usual care (Hvid T, et al. 2015). The participants in the exercise group showed significant improvements in triglycerides, adiponectin, IGF-1, IGFBP-1 and fasting glucose levels.

Adiponectin is a hormone involved in glucose regulation and fatty acid oxidation. IGF-1 is a growth factor and IGFBP-1 stands for IGF-1 binding protein which alters IGF-1 interaction with cell receptors. What is especially interesting is that PSADT (PSA doubling time) increased from 28 to 76 months during the first 6 months of exercise.

PSADT is a calculated number, and a higher value is associated with a reduced risk of disease progression.

None of these changes were taking place in the control group.

This is good news.

Exercise by itself makes a difference, but the smart thing to do is to also incorporate an effective dietary regime as well as stress reduction.

 

Hvid T1, Lindegaard B1, Winding K1, Iversen P2, Brasso K2, Solomon TP1,3, Pedersen BK1, Hojman P4. Effect of a 2-year home-based endurance training intervention on physiological function and PSA doubling time in prostate cancer patients. Cancer Causes Control. 2015 Nov 16. [Epub ahead of print]

 

Can you reverse the progression of prostate cancer with lifestyle changes?

Posted by on Cancer, Prostate cancer | 0 comments

Yes you can, research has shown that it is possible.

The participants in this study were men who had chosen not to undergo any conventional treatment (Ornish D, et al. 2005). These men had a PSA of 4-10 ng/ml and cancer Gleason scores of less than 7.

One group was asked to eat a vegan diet, participate in a stress reduction program, and do light exercises. The control group underwent the usual care. The study lasted for 1 year.

The PSA decreased 4% in the experimental group while it increased 6% in the control group.

6 patients in the control group underwent conventional treatment due to increased PSA and/or a progression of disease as shown on MRI, but none of the patients in the experimental group did.

Implementation of diet and lifestyle changes makes even more sense as a preventative measure.

 

Ornish D1, Weidner G, Fair WR, Marlin R, Pettengill EB, Raisin CJ, Dunn-Emke S, Crutchfield L, Jacobs FN, Barnard RJ, Aronson WJ, McCormac P, McKnight DJ, Fein JD, Dnistrian AM, Weinstein J, Ngo TH, Mendell NR, Carroll PR. Intensive lifestyle changes may affect the progression of prostate cancer. J Urol. 2005 Sep;174(3):1065-9; discussion 1069-70.

Tomatoes Influence Breast Cancer Risk

Posted by on Breast cancer, Cancer, Eating, Eye Health, General Health, Stay healthy, Wellness, Women, Womens health | 0 comments

You have probably heard that tomatoes are good for your eyes because of an antioxidant called lycopene. Did you know that tomatoes can make a difference with breast cancer risk? The reviewed research investigated just that (Llanos AA, et al. 2014).

Add tomatoes and fight breast cancer70 postmenopausal women at increased risk for breast cancer participated in the study. Their average age was 57.2 years. First they consumed a tomato-based diet which included at least 25 mg of lycopene daily for 10 weeks, and later they consumed a soy-based diet for 10 weeks which included at least 40 g of soy protein daily. The women were also tested for adiponectin and two other hormones.

Other research has documented a decreased risk for several types of cancers, including breast cancer when adiponectin is increasing(Kishida K, et Al. 2014).

When the subjects consumed the tomato-based diet, it was found that the adiponectin concentration increased. This indicates that tomato-based food is especially beneficial for women who are at higher risk for postmenopausal breast cancer. Don’t forget that tomatoes are beneficial for other things – especially your eyes!

 

 

 

 

Llanos AA1, Peng J, Pennell ML, Krok JL, Vitolins MZ, Degraffinreid CR, Paskett ED. Effects of tomato and soy on serum adipokine concentrations in postmenopausal women at increased breast cancer risk: a cross-over dietary intervention trial. J Clin Endocrinol Metab. 2014 Feb;99(2):625-32. doi: 10.1210/jc.2013-3222. Epub 2014 Jan 1.
Kishida K1, Funahashi T2, Shimomura I3. Adiponectin as a routine clinical biomarker. Best Pract Res Clin Endocrinol Metab. 2014 Jan;28(1):119-30. doi: 10.1016/j.beem.2013.08.006. Epub 2013 Aug 20.

Casual Soda Drinker? Don't go there!

Posted by on Bloodsugar, Cancer, Diabetes, Endometrial cancer, General Health, Glucose, Post menopausal, Women, Womens health | 0 comments

drinkSugar sweetened beverages have been associated with type 2 diabetes, obesity and other health problems. The reviewed research specifically investigated the relationship with sugar intake, sugar sweetened beverages and endometrial cancer(Inoue-Choi M, et al. 2013).

The participants were 23,039 postmenopausal women. From 1986 to 2010, 506 cases of estrogen dependent endometrial cancers were identified.
When compared with women who never drank sugar sweetened beverages, the cancer risk was 78 percent higher for the women in the highest quintile.

A higher risk for endometrial cancer was also found with higher sugar intake.

Sugar and sweets are seriously a major health hazard increasing the risk for many types of chronic conditions. You will reduce the risk for all of these health hazards by changing the habit of consuming sugar and sugar sweetened beverages.

 

 

 

Inoue-Choi M, Robien K, Mariani A, Cerhan JR, Anderson KE. Sugar-Sweetened Beverage Intake and the Risk of Type I and Type II Endometrial Cancer among Postmenopausal Women. Cancer Epidemiol Biomarkers Prev. 2013 Nov 22. [Epub ahead of print]