Your Road to Wellness

BMI

What’s important for the cardiovascular system is also important for the immune system.

Posted by on 9:00 am BMI, Body fat, Body mass index, Cardiovascular Disease, Cardiovascular disease & waist-hip ratio, Diet, Eating, General Health, Health Risk, Inflammation, Weight, Weight loss | 0 comments

obese man with burgers

 

In this study, participants taking berberine when compared to the placebo group saw a
reduction in triglycerides by 35.9% total cholesterol by 18.1% and LDL (low-density lipoprotein),
the so-called bad cholesterol by 21.1% (Zhang Y, et.al., 2008).

Patients with metabolic syndrome treated with berberine for 3 months showed a decrease in
their BMI (body mass index) from 31.5 to 27.4 in this study (Yang J, et.al., 2012).
Patients diagnosed with the metabolic syndrome usually have several symptoms, they are
insulin resistant, have increased waist circumference and high blood pressure.
The same research also showed that berberine decreased leptin levels from 8.01 to 5.12 μg/L.
Leptin is a hormone that suppresses food intake and induces weight loss. Obese patients are
usually leptin-resistant.

 

 

When 10 studies were reviewed both BMI and waist circumference decreased in participants
taking berberine (Xiong P, et.al.,2020).

It is important to produce a balanced immune response when needed.
An overreaction of the immune system will cause damage and is harmful. It can actually kill us.
Some people are killed by an overreaction of their immune system, not from the invading virus
or bacteria.

This research showed that berberine had an anti-inflammatory effect and initiated a more
balanced immune response (Kalmarzi RN, et.al.,2019).
Inflammation is also a risk factor for cardiovascular disease.

When researchers treated patients with the acute coronary syndrome with berberine, they found
that several inflammatory markers were reduced, C-reactive protein and interleukin-6 were 2 of
them (Meng S, et.al., 2012).

Berberine has shown to be a very useful plant-derived compound benefitting important
functions from blood glucose metabolism, cardiovascular function, fat storage, immune
system and inflammation.

These functions are interconnected, that is why berberine is such a valuable substance.

 

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References:

Kalmarzi RN, Naleini SN, Ashtary-Larky D, Peluso I, Jouybari L, Rafi A, Ghorat F, Heidari N,
Sharifian F, Mardaneh J, Aiello P4, Helbi S, Kooti W.Anti-Inflammatory and Immunomodulatory
Effects of Barberry ( Berberis vulgaris ) and Its Main Compounds.Oxid Med Cell Longev. 2019
Nov 19;2019:6183965.

Meng S, Wang LS, Huang ZQ, Zhou Q, Sun YG, Cao JT, Li YG, Wang CQ. Berberine
ameliorates inflammation in patients with acute coronary syndrome following percutaneous
coronary intervention. Clin Exp Pharmacol Physiol. 2012 May;39(5):406-11.

Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning
G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab. 2008 Jul;93(7):2559-65.

Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Berberine improves insulin sensitivity by
inhibiting fat store and adjusting adipokines profile in human preadipocytes and metabolic
syndrome patients. Evid Based Complement Alternat Med. 2012;2012:363845

Xiong P, Niu L, Talaei S, Kord-Varkaneh H, Clark CCT, Găman MA, Rahmani J, Dorosti M,
Mousavi SM, Zarezadeh M, Taghizade-Bilondi H, Zhang J. The effect of berberine
supplementation on obesity indices: A dose- response meta-analysis and systematic review of
randomized controlled trials. Complement Ther Clin Pract. 2020 May;39:101113.

 

glucose metabolism supportThis formula was designed to support healthy glucose metabolism and the cardiovascular system.

The research referred to below was conducted with participants who had type 2 diabetes. This does not mean that you have to have type 2 diabetes to take this formula.

It’s very important to have a healthy glucose metabolism and keep the blood glucose low. You want to take this formula and keep your glucose metabolism healthy.

Healthy glucose metabolism is important to keep your cardiovascular system healthy.

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Walk fast to get help with with weight loss.

Posted by on 1:00 pm BMI, BMJ Formula, Body fat, Body mass index, Exercise, Exercise, Get in shape, Lose fat, Sports performance, Vigorous Activity, Waist circumference, Weight, Weight loss | 0 comments

Running on treadmillWalking has been promoted as an easy way to lose weight and stay in shape, but is it really effective? That is exactly what the reviewed researched investigated.

The participants a total of 4511 adults aged 18-64 years were included in the study(Fan JX, et al. 2013). The body mass index (BMI) were measured and accelerometers were used to evaluate minutes per day of high intensity bouts of walking of either 10 minutes or more, or less than 10 minutes. This was compared with lower intensity walking of 10 minutes or more per day and lower intensity walking of less than 10 minutes per day.

It was found that both higher intensity short-duration or walking long-duration were related to reduced BMI or risk of overweight/obesity. Neither the short walks or the long walks of lower intensity were found to have a positive effect on BMI or risk of overweight/obesity.

The message is that even less than 10 minutes of walking per day can help you prevent weight gain if it is high intensity walking. This is another example showing that it is the intensity of the exercise you do that is important, not the time you spend doing it. The more intense you exercise, the less time you need to spend doing it.

 

 

 

Fan JX, Brown BB, Hanson H, Kowaleski-Jones L, Smith KR, Zick CD Moderate to vigorous physical activity and weight outcomes: does every minute count? Am J Health Promot. 2013 Sep-Oct;28(1):41-9. doi: 10.4278/ajhp.120606-QUAL-286. Epub 2013 Mar 4.

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Factors affecting cognition

Posted by on 11:21 am BMI, Brain, Health | 0 comments

Decline of memory is one of the major concerns as we get older. The reviewed research investigated factors affecting memory, and it is an important study because these are things we can do something about (Singh-Manoux A, et al. 2012).

The participants were 6,401 adults, aged 39-63 years in 1991-1993. Data on weight using body mass index (BMI) was collected and metabolic status was evaluated using triglycerides, high density lipoprotein (HDL). The participants were also evaluated for the use of lipid lowering drugs, if they had high blood pressure or if they were using blood pressure medications. Glucose was measured and it was recorded if the participants were using medications for diabetes. Four cognitive tests were administered in 1997-1999, 2002-2004, and 2007-2009. Abnormality of the metabolic status was defined as 2 or more of the above listed factors.

The results documented a faster cognitive decline in the participants with both obesity and metabolic abnormality.

The good news about this is that these are factors we can do something about by adapting a healthy lifestyle and eating habits. For a program that works, read more about Learn to Eat.

 

 

Singh-Manoux A, Czernichow S, Elbaz A, Dugravot A, Sabia S, Hagger-Johnson G, Kaffashian S, Zins M, Brunner EJ, Nabi H, Kivimäki M. Obesity phenotypes in midlife and cognition in early old age: the Whitehall II cohort study. Neurology. 2012 Aug 21;79(8):755-62. doi: 10.1212/WNL.0b013e3182661f63.

 

It is not only how much you weigh, but where you carry your weight that is important.

Posted by on 8:58 pm BMI, Body fat, Body mass index, Risk of death, Waist-to-hip ratio | 0 comments


The latest research on the association of body fat and the risk of death was just published in the New England Journal of Medicine, a very prestigious publication (Pischon T, et al, 2008). Most of the studies in the past have relied on the body mass index (BMI) and only few have examined if it is important where the fat is distributed.

This study however, which was really large, it included 359,387 participants from nine countries in Europe, looked at both BMI, waist circumference and waist-to-hip ratio as it relates to the risk of death. The follow-up was 9.7 years.

The lowest risks of death were observed at a BMI of 25.3 for men and 24.3 for women. The researchers also found that waist circumference and waist-to-hip ratio were strongly associated with the risk of death, the bigger waist circumference and the bigger waist-to-hip ratio, the higher was the risk of death.

The investigations concluded that both general adiposity and abdominal adiposity are associated with the risk of death.

 

References:

Pischon T, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med. 2008 Nov 13;359(20):2105-20.