Your Road to Wellness

Antioxidents

Can green tea extract help prevent influenza virus?

Posted by on 9:00 am Antioxidents, Cholesterol, Green tea, Inflammation | 0 comments

influenza virus

 

Viral infections are a constant threat. Every year people get sick from the influenza virus.
In addition to eating healthy and being physically active, what else can you do?
How about using green tea.
Researchers in Japan tried to find additional resources and investigated if capsules with green
tea extract including catechins and theanine could be effective in preventing the flu (Matsumoto
K, et al, 2011).
This was a randomized, double-blind, placebo-controlled trial of 200 healthcare workers
conducted for 5 months.
The researchers found that the incidence of clinically defined influenza infection was
significantly lower in the catechin/theanine group.

 

 

Research has also shown that green tea extract lowers blood pressure, total cholesterol, LDL
(the bad cholesterol), and inflammation (Nantz MP, et al 2009). These are all risk factors for
cardiovascular disease.
It is also important what green tea can do for the brain. Green tea may provide neuroprotection
and has been associated with a lower prevalence of cognitive impairment (Kuriyama S, et al
2006).

References:

Kuriyama S, Hozawa A, Ohmori K, Shimazu T, Matsui T, Ebihara S, Awata S, Nagatomi R, Arai H,
Tsuji I. Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya
Project. American Journal of Clinical Nutrition, Vol. 83, No. 2, 355-361, February 2006.

Matsumoto K, Yamada H, Takuma N, Niino H, Sagesaka YM.
Effects of green tea catechins and theanine on preventing influenza infection among
healthcare workers: a randomized controlled trial. BMC Complement Altern Med. 2011
Feb 21;11:15.

Nantz MP, Rowe CA, Bukowski JF, Percival SS. Standardized capsule of Camellia sinensis lowers
cardiovascular risk factors in a randomized, double-blind, placebo-controlled study. Nutrition. 2009
Feb; 25(2):147-54. Epub 2008 Oct 9.

 

BETTER GREEN TEA

better green tea

Polyphenols (catechins) are the active ingredients in green tea providing a variety of benefits.

Green tea extract has been documented to lower blood pressure, reduce total cholesterol and LDL (the bad cholesterol), reduce serum amyloid-alpha (a marker of chronic inflammation) and reduce malondialdehyde (a marker of oxidative stress) (Nantz MP, et al. 2009). These are all cardiovascular risk factors and they were reduced in only 3 weeks.

Green tea may provide neuroprotection and has been associated with a lower prevalence of cognitive impairment.

A study including 41,761 participants found that green tea consumption was associated with a reduced risk of liver cancer.

Green tea polyphenols have been documented to reduce serum biomarkers in patients with prostate cancer.

Regular drinking of green tea has been associated with a slightly decreased risk of breast cancer (Shrubsole MJ, et al. 2008).

Green tea consumption was inversely associated with psychological distress in an assessment of 42,093 individuals. Consumption of 4 cups or more of green tea has been associated with a lower prevalence of depressive symptoms.

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This antioxidant is lower in neurodegenerative diseases like Alzheimer’s.

Posted by on 8:32 am Alzheimer’s, Antioxidents, Brain, Dementia, Nervous System | 0 comments

 

This antioxidant is lower in neurodegenerative diseases like Alzheimer’s.

 

There are good reasons why the body produces its own antioxidant enzymes.

All tissues including the nervous system and the brain are exposed to free radical damage.

The most important antioxidant the body is making is probably glutathione.

Humans with neurodegenerative and neuropsychiatric disorders have demonstrated altered levels of glutathione and oxidized glutathione (Gu F, et.al., 2015).  A decreased ratio of glutathione to oxidized glutathione has been found in the blood and brain of these individuals.

 

 

Glutathione depletion can lead to abnormalities of a mitochondrial function where the cells make energy. A few studies have shown that glutathione deficiency occurs prior to neuropathological abnormalities.

These researchers found that glutathione was significantly decreased in the red blood cells from male patients with Alzheimer’s disease (Liu H, et.al., 2004).

 

 

The most common form of glutathione is reduced glutathione, but don’t take that. This form of glutathione is oxidized in the stomach and does not provide many benefits.

S-acetyl glutathione on the other hand gets into the cells where it’s needed (Cacciatore I, et al., 2010).

 

References:

Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A.Prodrug approach for increasing cellular glutathione levels.Molecules. 2010 Mar 3;15(3):1242-64.

Gu F, Chauhan V, Chauhan A.Glutathione redox imbalance in brain disorders.Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):89-95.

Liu H, Wang H, Shenvi S, Hagen TM, Liu RM.Glutathione metabolism during aging and in Alzheimer disease.Ann N Y Acad Sci. 2004 Jun;1019:346-9.

 

Effective S-Acetyl Glutathione

  • Glutathione is your primary defense against aging.
  • Glutathione helps detoxify your body.
  • Regular glutathione is not very bio-available, but this problem has now been solved when using S-Acetyl Glutathione which is very effective.
  • Increased oxidative stress and lower antioxidant levels are associated with mood disorders and depression.

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Heart Health and How to Fight Back Against Disease

Posted by on 11:00 am Antioxidents, General Health, Glutathione, Wellness | 0 comments

 

This substance is very important for the cardiovascular system.

Oxidative stress has been found to be a factor involved in many chronic diseases, and cardiovascular disease is one of them.

This is what was found in the following research when glutathione levels were measured in patients with cardiac disease and compared with a healthy control group. 

The researchers wrote that this study provides evidence that cardiac and systemic glutathione deficiency is related to the functional status and structural cardiac abnormalities of patients with cardiac diseases (Damy T, et.al., 2009).

Another study found that glutathione concentrations were lower in all cardiovascular disease cases when compared to the control group (Shimizu H, et.al., 2004). 

Both the cerebral infarction cases and cerebral hemorrhage cases had significantly lower total glutathione levels when compared to the control groups.

The researchers wrote that these findings suggest that reduced plasma total glutathione levels are a risk factor for cardiovascular disease, especially for cerebral small vessel disease.

In patients with coronary artery disease, a low level of activity of red-cell glutathione peroxidase 1 was independently associated with an increased risk of cardiovascular events.

The risk of cardiovascular events was inversely associated with increasing quartiles of glutathione peroxidase 1 activity (Blankenberg S, et.al., 2003).  

The researchers found that glutathione peroxidase 1 activity was among the strongest univariate predictors of the risk of cardiovascular events. 

 

They also wrote that  increasing glutathione peroxidase 1 activity might lower the risk of cardiovascular events.  

References

Blankenberg S, Rupprecht HJ, Bickel C, Torzewski M, Hafner G, Tiret L, Smieja M, Cambien F, Meyer J, Lackner KJ; AtheroGene Investigators.Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease.N Engl J Med. 2003 Oct 23;349(17):1605-13.

Damy T, Kirsch M, Khouzami L, Caramelle P, Le Corvoisier P, Roudot-Thoraval F, Dubois-Randé JL, Hittinger L, Pavoine C, Pecker F .Glutathione deficiency in cardiac patients is related to the functional status and structural cardiac abnormalities. PLoS One. 2009;4(3):e4871.

Shimizu H, Kiyohara Y, Kato I, Kitazono T, Tanizaki Y, Kubo M, Ueno H, Ibayashi S, Fujishima M, Iida M. Relationship between plasma glutathione levels and cardiovascular disease in a defined population: the Hisayama study. Stroke. 2004 Sep;35(9):2072-7.

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

BioPro, Inc. Tissue Recovery is using the patented form of S-Acetyl Glutathione from the Italian company that has the patent for S-Acetyl Glutathione.

Click here to get your bottle of the most effective form of glutathione!

 

 

 

Antioxidants in joint fluid are reduced in osteoarthritis. This is what you can do.

Posted by on 6:50 am Antioxidents, Arthritis, BMJ Formula, Exercise, Joint health, Supplements, Supplements for Conditions, Supplements List | 0 comments

Excess reactive oxygen species and oxidative damage have been associated with the pathogenesis of osteoarthritis.  Joint fluid from patients with osteoarthritis is characterized by significantly decreased extracellular superoxide dismutase (SOD) levels, a significantly decreased glutathione level, and ascorbate when compared to knee joints with intact cartilage (Regan EA, et.al., 2008).

SOD is one of the body’s antioxidant enzymes and glutathione is the body’s most effective antioxidant.  These changes in joint fluid antioxidants are likely to accelerate the oxidative damage of the cartilage.

The body needs copper, zinc, and manganese to produce SOD, so one of the things you can do to help prevent cartilage degeneration is to take these minerals.  The glutathione level was also reduced, and you can also take S-Acetyl Glutathione to increase cellular glutathione (Cacciatore I, et.al., 2010).

Don’t make the mistake and supplement with reduced glutathione which is the most common form on the market.  No significant changes were observed in biomarkers of oxidative stress, including glutathione status of oral glutathione supplementation (Allen J, Bradley RD, 2011).

References

Allen J, Bradley RD.Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. J Altern Complement Med. 2011 Sep;17(9):827-33.

Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A. Prodrug approach for increasing cellular glutathione levels. Molecules. 2010 Mar 3;15(3):1242-64.

Regan EA, Bowler RP, Crapo JD.Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury.  Osteoarthritis Cartilage. 2008 Apr;16(4):515-21.

 

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

BioPro, Inc. Tissue Recovery is using the patented form of S-Acetyl Glutathione from the Italian company that has the patent for S-Acetyl Glutathione.

Click here to get your bottle of the most effective form of glutathione!

 

 

 

 

 

You may know that you need calcium, but maybe you have heard that taking calcium may cause calcification of blood vessels.

Taking calcium by itself is not a good idea. You need to take calcium in a formula that includes multiple nutrients, and it needs to include magnesium. That’s one of the reasons the BMJ contains a large amount of magnesium in a very well absorbed form.

Click here to improve your bone, muscle, and joint health!

What can we do to reduce oxidative stress as we get older?

Posted by on 1:48 am Anti-aging, Antioxidents, General Health, Health, Health Risk, Stress | 0 comments

We know that aging is associated with oxidative stress.  This research tested whether glutathione deficiency occurs because of diminished synthesis and contributes to oxidative stress and what could be done about it (Sekhar RV, et.al., 2011).

Two groups that were divided into age groups made up the participants.  Both older and younger participants were infused with glycine and measured for red blood cell (RBC) glutathione synthesis and concentrations, plasma oxidative stress, and markers of oxidative damage.

Compared with the younger participants, the elderly participants had markedly lower RBC concentrations of glycine, cysteine and glutathione synthesis and higher oxidative stress.

After infusion with glycine, glutathione synthesis increased significantly and oxidative stress decreased significantly. No difference was found between the older and the younger participants after the infusion.                                                                  

The researcher stated that glutathione deficiency in elderly humans occurs because of a marked reduction in synthesis.

Does this mean that you have to go and have infusions all the time?

No, it‚Äôs not that complicated anymore. ¬†You can supplement with S-Acetyl Glutathione, which is a very effective form of glutathione and gets it into the cells where it‚Äôs needed (Cacciatore I, et.al., 2010). ¬†¬†Don‚Äôt make the mistake and supplement with reduced glutathione–which is the most common form on the market. No significant changes were observed in biomarkers of oxidative stress, including glutathione status of oral glutathione supplementation (Allen J, Bradley RD, 2011).

References

Allen J, Bradley RD.Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. J Altern Complement Med. 2011 Sep;17(9):827-33.

Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A. Prodrug approach for increasing cellular glutathione levels.Molecules. 2010 Mar 3;15(3):1242-64.

Sekhar RV1, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F, Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr. 2011 Sep;94(3):847-53.

 

 

Glutathione helps your cells reduce free radical damage and also helps lower inflammation.

BioPro, Inc. Tissue Recovery is using the patented form of S-Acetyl Glutathione from the Italian company that has the patent for S-Acetyl Glutathione.

Click here to get your bottle of the most effective form of glutathione!

What can blueberries do for you?

Posted by on 1:49 am Anti-aging, Antioxidents, BMJ Formula, Diet, Diet, General Health, Stay healthy, The Learn to Eat Plan, Tissue Recovery Blog, Wellness | 0 comments

Blueberries contain flavonoids and it is the flavonoids that provide all the health benefits.

The following study showed that daily 1-month blueberry consumption increased flow-mediated dilation as well as lowered systolic blood pressure (Rodriguez-Mateos A, et.al., 2019).

The more blueberries are researched, the more impressive they look.

Flow-mediated dilation is a measurement of endothelial function (the endothelium is the inner lining of the blood vessels).

When flow-mediated dilation was measured in healthy men after blueberry flavonoid intake, the researchers found a dose-dependent increase up to an intake of 766 mg polyphenols (Rodriguez-Mateos A, et.al., 2013). The increase was seen from 1-6 hours after the intake.

Blueberries can be used to help protect the blood vessels from damage as the following study shows.

Human aortic endothelial cells showed a reduced expression of inflammatory markers after being exposed to substances found from blueberry consumption (Cutler BR, et.al., 2018).

100 g of blueberries twice daily would give you protection the whole day. While fresh blueberries are expensive, frozen blueberries are better priced.  Adding blueberries to your diet daily would give you these benefits.

References

Cutler BR, Gholami S, Chua JS, Kuberan B, Anandh Babu PV.Blueberry metabolites restore cell surface glycosaminoglycans and attenuate endothelial inflammation in diabetic human aortic endothelial cells. Int J Cardiol. 2018 Jun 15;261:155-158.

Rodriguez-Mateos A, Istas G, Boschek L, Feliciano RP, Mills CE, Boby C, Gomez-Alonso S, Milenkovic D, Heiss C,Circulating anthocyanin metabolites mediate vascular benefits of blueberries: insights from randomized controlled trials, metabolomics, and nutrigenomics. J Gerontol A Biol Sci Med Sci. 2019 Feb 16. pii: glz047.

Rodriguez-Mateos A, Rendeiro C, Bergillos-Meca T, Tabatabaee S, George TW, Heiss C, Spencer JP.Intake and time dependence of blueberry flavonoid-induced improvements in vascular function: a randomized, controlled, double-blind, crossover intervention study with mechanistic insights into biological activity. Am J Clin Nutr. 2013 Nov;98(5):1179-91.

 

 

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