Your Road to Wellness

Posts by Dr. Sopler

Can your blood glucose regulation affect your memory?

Posted by on 12:45 pm Bloodsugar, Cognition, Dementia, Diabetes, Diet, Eating, General Health, Glucose, Health Risk, Insulin resistance, Memory, Wellness | 0 comments

This study investigated how the ability to control the levels of blood glucose was related to mood and cognition (Young H, Benton D, 2014).

155 adults, aged 45-85 years,  without a diagnosis of diabetes, were given an oral glucose tolerance test and cognitive tests. 

The researchers found that those with poorer glucose tolerance forgot more words and had slower decision times, but only if they were 61 years or older. 

The next study on the same topic included 93 healthy male and female non-diabetic participants who ranged in age from 55 to 88 years (Messier C, 2010). 

The researchers measured cognitive function as well as other things. The participants also had a glucose tolerance test during which glucose and insulin were measured.This was done after drinking a saccharin solution and on another occasion after drinking a glucose solution (50 g).

The results showed that progressively worse glucose regulation predicted poorer performance on measures of working memory and executive function.

The researchers stated that the results suggest that cognitive functions may be impaired before gluco-regulatory impairment reaches levels consistent with a type 2 diabetes diagnosis.

The change from being insulin sensitive to being insulin resistant is a gradual process. This shows that it is really important to keep your blood glucose at a low and normal level not only after you have fasted, but also after eating. Ideally it should be below 90 two hours after a meal.

The sooner you  implement strategies to stay insulin sensitive the better it is.

You can stay insulin sensitive by making changes to the way you eat and by incorporating exercise into your routine.

References

Messier C, Tsiakas M, Gagnon M, Desrochers A. Effect of age and glucoregulation on cognitive performance. J Clin Exp Neuropsychol. 2010 Oct;32(8):809-21.

Young H, Benton D.The nature of the control of blood glucose in those with poorer glucose tolerance influences mood and cognition. Metab Brain Dis. 2014 Sep;29(3):721-8.

 

 

 

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Adding this to your exercise routine will help improve cognition.

Posted by on 2:37 pm Anti-Aging, Cognition, Exercise, General Health, Get in shape | 0 comments

 

We know that sedentary behaviour is associated with impaired cognition and exercise can improve cognition.

This research is interesting because it added a component to the exercise (Wheeler MJ, et.al., 2019).

The participants were sedentary overweight/obese older adults with normal cognitive function. Cognitive testing were done and brain-derived neurotrophic growth factor (BDNF) was assessed.

The study consisted of 3 different protocols which the participants completed with 6 days in between.

One time they were sitting uninterrupted for 8 hours which was the control condition. Another time they were sitting for 1 hour, then they did moderate-intensity walking for 30 minutes and uninterrupted sitting for 6.5 hours.  The third protocol were sitting for 1 hour, then moderate-intensity walking for 30 min, and sitting interrupted every 30 min with 3 minutes of light-intensity walking for 6.5 hours.

The results showed that moderate-intensity walking for 30 min, and sitting interrupted every 30 min with 3 minutes of light-intensity walking improved blood levels of BDNF and working memory or executive function.

This means that we need to be active throughout the day. Just set reminders to take short breaks and do an activity that increases your pulse rate. 

It does not mean that you have to get out and walk for 3 minutes. There are other things you can do for just a couple of minutes or less without going outside, so you have a very minimal interruption.

Reference

Wheeler MJ1,2, Green DJ3, Ellis KA4, Cerin E5,6, Heinonen I3,7, Naylor LH3, Larsen R2, Wennberg P8, Boraxbekk CJ9,10, Lewis J, Eikelis N2,11, Lautenschlager NT12, Kingwell BA13, Lambert G11, Owen N14,15, Dunstan DW, Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition.Br J Sports Med. 2019 Apr 29. pii: bjsports-2018-100168.

 

 

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The importance of this vitamin and why some people may not be getting enough of it

Posted by on 8:42 am Eating, General Health, Health, Stay healthy, Supplements, Supplements for Conditions, Vitamin B | 0 comments

Thiamine vitamin B1 is an essential cofactor for 4 enzymes involved in the production of energy (ATP) and the synthesis of essential cellular molecules. 

The total body stores of thiamine are relatively small, and thiamine deficiency can develop  secondary to inadequate nutrition, high alcohol consumption, increased urinary excretion and acute metabolic stress (Attaluri P, et.al., 2018).

We need to keep in mind that we don’t have to have severe deficiencies of vitamins to develop symptoms that may not be recognized as caused by marginal deficiencies.

Fast food consumption will not provide adequate levels of nutrients even if they usually provide excess calories. Alcohol makes us use more of the B vitamins. 

It is also quite common to experience an increase in urinary excretion as we get older. Many men and women have to get up several times during the night, even if they are not very old. This makes us excrete more of both minerals and vitamins, especially the B vitamins which are water soluble.

Thiamine deficiency has been suggested to be associated with many cardiovascular diseases  and risk factors including type 1 and type 2 diabetes, obesity, chronic vascular inflammation, dyslipidemia, heart failure, myocardial infarction, nerve conduction defects, and depression (Eshak ES, Arafa AE, 2018).  A lot of people die of cardiovascular disease, and thiamine deficiency could play a role in the development of that.

Remember thiamine is only one of the B vitamins, and they are all very important.

Reduced bioavailability is a major limiting factor of regular thiamine.  To overcome this issue benfotiamine a form of thiamine which is much more bioavailable was developed (Ray V, et.al., 2018).

A high quality vitamin B-complex should contain this form of vitamin B1 in addition to better bioavailable forms of some of the other B vitamins.

References

Attaluri P, Castillo A, Edriss H, Nugent K.Thiamine Deficiency: An Important Consideration in Critically Ill Patients. Am J Med Sci. 2018 Oct;356(4):382-390. 

Eshak ES, Arafa AE. Thiamine deficiency and cardiovascular disorders. Nutr Metab Cardiovasc Dis. 2018 Oct;28(10):965-972. Nutr Metab Cardiovasc Dis. 2018 Oct;28(10):965-972.

Raj V, Ojha S, Howarth FC, Belur PD, Subramanya SB. Therapeutic potential of benfotiamine and its molecular targets. Eur Rev Med Pharmacol Sci. 2018 May;22(10):3261-3273.

This is not a regular B vitamin formula.

The B1 (thiamine), B2 (riboflavin), B6 (pyridoxine), and B12 (cobalamin) comes in their physiologically active form, making them easier to absorb.

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This is affected by too little quality sleep

Posted by on 8:03 am General Health, Research, Sleep, Wellness | 0 comments

The following was a small study, but it is interesting because the participants were young females and males with an average age of 28.8 years (Montesinos L, et.al., 2018).

Their average body mass index was 23.4 and their resting heart rate was 63.1 which are considered good.  Sleep and balance were assessed over two days, and balance was assessed in a gait lab.

Even in young people like, this decreased sleep quality for only a short time was causing problems.

The participants with a day-to-day deterioration in sleep quantity and quality saw significant changes in balance.  

Sleep quantity and quality were defined by decreased duration and increased fragmentation, increased night time activity and decreased heart rate variability.  As more and more research is done in the area of sleep, we discover how important sleep really is, even balance is affected by sleep. Maybe that’s one of the reasons why some people lose their balance as they get older.

If you have problems relaxing, try meditation, especially in the evening in a room without bright light.

Reduce your exposure to bright light and light from computer screens some time before you go to bed.   Exposure to bright light in the evening can alter your circadian rhythm and affect the release of the hormone melatonin, making it more difficult to get quality sleep.

Reference

Montesinos L, Castaldo R, Cappuccio F, Pecchia L, Day-to-day variations in sleep quality affect standing balance in healthy adults. Sci Rep. 2018 Nov 30;8(1):17504.

 

 

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Is there an effective way to lower blood pressure without medications?

Posted by on 12:13 pm Anti-aging, Blood Pressure, Blood triglycerides, Flaxseeds, Health Risk | 0 comments

 

It is very common–even if it is not necessary–to see that the blood pressure is increasing with age.   With medications, blood pressure usually comes down, but it may still not be as low as we would like it to be. Blood pressure medications also comes with side effects.

What else can we do?

A low glycemic index high nutrient diet and regular exercise would make a big difference, but there is also something else you can do which has shown to reduce blood pressure as effectively as medication for those with high blood pressure. It is also simple to implement.

This is the research.

The study examined the effects of daily ingestion of flax seeds on systolic and diastolic blood pressure (Rodriguez-Leyva D, et.al., 2013).  It was a double-blinded, placebo-controlled, randomized trial, 110 patients ingested a variety of foods that contained 30 g of milled flax seed or a placebo each day for 6 month.

After 6 months the systolic blood pressure was 10 mm Hg lower and the diastolic pressure was 7 mm Hg lower in the flax seed group compared to the placebo group.

For the participants that had a systolic blood pressure of 140 mm Hg or higher, it was an even better response with a reduction of 15 mm Hg for systolic pressure and 7 mm Hg reduction for diastolic pressure for those who ingested the flax seeds.

You can buy organic raw flax seeds and grind them in a coffee grinder for 10-15 seconds.

Either add them to different foods, or just put them in a glass, add some water and drink it down. It’s as easy as that.

Reference

Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN.Potent antihypertensive action of dietary flaxseed in hypertensive patients.Hypertension. 2013 Dec;62(6):1081-9.

 

 

 

Learn to Eat Program

Based on the most effective scientific strategies, this program was created to help
you reduce inflammation and feel great.

Read more…