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Derivative of broccoli sprouts improves detoxification and provides cancer protection We have all heard that cruciferous vegetables like broccoli are very healthy. Now we have even more evidence. Recent research has shown that sulforaphane which is derived from broccoli sprouts supports liver detoxification and also has cancer protective properties. Sulforaphane has been found to enhance the phase II detoxification enzymes of the liver providing added protection from toxins (Ritz SA, et al. 2007). It is stated in several articles that sulforaphane is a promising substance for cancer prevention and treatment including those involving increased inflammation, viral or bacterial pathologies (disease processes) (Tang L, et al. 2006. Myzak MC, Dashwood RH. 2006). In human prostate cancer cells, sulforaphane has shown to induce apoptosis (cell death) (Herman-Antosiewicz A., et al. 2006). It has also been documented that sulforaphane has activated multiple molecular mechanisms for apoptosis in glioblastoma cells which is a very serious form of brain tumor cells (Karmakar S, et al. 2006). Since sulforaphane is a potent antioxidant and detoxifier, BioPro, Inc. now offer this in a formula called “Antiox Detox Support”. Wishing you the best of health, Didrik
References: Herman-Antosiewicz A, Johnson DE, Singh SV. Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells. Cancer Res. 2006 Jun 1;66(11):5828-35. Karmakar S, Weinberg MS, Banik NL, Patel SJ, Ray SK. Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphane. Neuroscience. 2006 Sep 1;141(3):1265-80. Epub 2006 Jun 12. Myzak MC, Dashwood RH. Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Lett. 2006 Feb 28;233(2):208-18. Ritz SA, Wan J, Diaz-Sanchez D. Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L33-9. Epud 2006 Aug 11. Tang L, Zhang Y, Jobson HE, Li J, et al. Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract. Mol Cancer Ther. 2006 Apr;5(4):935-44.
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