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Dietary cis-monounsaturated fatty acids and metabolic control in type 2 diabetes.
Ros E.
Lipid Clinic, Nutrition & Dietetics Service, Institut d'Investigacions Biomediques August Pi Sunyer (IDIBAPS), Hospital Clinico, University of Barcelona, Barcelona, Spain. eros@medicina.ub.es
Whether low-fat, high-carbohydrate (CHO) diets or moderately high-fat, high-monounsaturated fatty acid (MUFA) diets are preferable for the treatment and prevention of diabetes has been a matter of debate. High-fat diets based on MUFA-rich oils or whole foods have been compared with high-CHO diets for effects on several cardiovascular risk outcomes in diabetic subjects. Early studies using metabolic diets with wide differences in total fat content (15-25% of energy) generally found a beneficial effect of MUFA diets on glycemic control and serum lipids. Recent studies using prescribed diets with a difference of Limited experimental evidence suggests that MUFA diets favorably influence blood pressure, coagulation, endothelial activation, inflammation, and thermogenic capacity. Energy-controlled high-MUFA diets do not promote weight gain and are more acceptable than low-fat diets for weight loss in obese subjects. Thus, there is good scientific support for MUFA diets as an alternative to low-fat diets for medical nutrition therapy in diabetes.
PMID: 12936956 [PubMed - indexed for MEDLINE]